CIF21 DIBBs: PD: Accelerating Comparative Metagenomics through an Ocean Cloud Commons
CIF21 DIBBs: PD: Accelerating Comparative Metagenomics through an Ocean Cloud Commons
批准号:
1640775
负责人:
Bonnie Hurwitz
金额:
$49.61万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2017
资助国家:
美国
项目状态:
已结题
起止时间:
2017-01-01 至 2019-12-31
中文摘要
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英文摘要
The Tara Oceans Expedition has provided the largest publicly available contiguous dataset available in genomics for any scientific project in the world. Using the research schooner Tara and modern sequencing and state-of-the-art imaging technologies, a multinational team of scientists sampled microscopic plankton at hundreds of sites and depths in all the major oceanic regions. The Tara Oceans Expedition data have been released, but it is a challenge for researchers to access, manipulate, and analyze such large-scale resources. This project creates an Ocean Cloud Commons (OCC), a cloud-based resource and repository allowing researchers to query the Tara Oceans Expedition Data in the cloud; it also makes available comparative metagenomic tools through the Ocean Treasure Box (OTB).The Ocean Cloud Commons and Ocean Treasure Box build upon established partnerships with organizations such as CyVerse Cyberinfrastructure, Agave Platform, OpenCloud, and computing facilities at the Texas Advanced Computing Center. The Ocean Cloud Commons uses an algorithm based on MapReduce to create a comparative metagenomics data resource in a Hadoop big data framework. The OCC can be widely accessed by researchers using tools developed in the Ocean Treasure Box and implemented as Apps in the CyVerse Cyberinfrastructure. Specifically, OTB tools deploy and compute on OCC data in OpenCloud via the Agave Platform and Developer API from CyVerse. Taken together, the OTB tools and OCC data resources enable researchers to address global-scale questions about the distribution of microbes across the sea that affect climate and ecosystem function.This award by the Advanced Cyberinfrastructure Division is jointly supported by the NSF Directorate for Biological Sciences (Division of Biological Infrastructure), and the NSF Directorate for Geosciences.
期刊论文(5)
专著(0)
科研奖励(0)
会议论文
DOI:
10.3389/fmicb.2019.00806
发表时间:
2019-04-16
期刊:
FRONTIERS IN MICROBIOLOGY
影响因子:
5.2
作者:
[Ponsero, Alise J., Hurwitz, Bonnie L.]
通讯作者:
Hurwitz, Bonnie L.
iMicrobe: Tools and data-driven discovery platform for the microbiome sciences
iMicrobe:微生物组科学的工具和数据驱动的发现平台
DOI:
10.1093/gigascience/giz083
发表时间:
2019
期刊:
GigaScience
影响因子:
9.2
作者:
[Youens-Clark, Ken, Bomhoff, Matt, Ponsero, Alise J, Wood-Charlson, Elisha M, Lynch, Joshua, Choi, Illyoung, Hartman, John H, Hurwitz, Bonnie L]
通讯作者:
Hurwitz, Bonnie L
Libra: Improved Partitioning Strategies for Massive Comparative Metagenomics Analysis
Libra:改进的大规模比较宏基因组分析的分区策略
DOI:
10.1145/3217880.3217882
发表时间:
2018
期刊:
Proceedings of the 9th Workshop on Scientific Cloud Computing
影响因子:
--
作者:
[Choi, Illyoung, Ponsero, Alise J., Youens-Clark, Ken, Bomhoff, Matthew, Hurwitz, Bonnie L., Hartman, John H.]
通讯作者:
Hartman, John H.
I-Corps: Rapid home microbiome diagnostic tests
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批准号:2022382
-
项目类别:Standard Grant
-
资助金额:$5.0万
-
财政年份:2020
-
负责人:Bonnie Hurwitz
-
依托单位:
Collaborative Proposal: EarthCube Building Blocks: Planet Microbe: Enabling the discovery and integration of oceanographic 'omics, environmental and physiochemical data layers
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批准号:1639588
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项目类别:Standard Grant
-
资助金额:$87.3万
-
财政年份:2017
-
负责人:Bonnie Hurwitz
-
依托单位:
海外基金