CIF21 DIBBs: PD: Accelerating Comparative Metagenomics through an Ocean Cloud Commons

塔拉海洋探险队为世界上任何科学项目提供了基因组学中最大的公开可用的连续数据集。 一个多国科学家小组利用研究用纵帆船塔拉号和现代测序及最先进的成像技术，在所有主要海洋区域的数百个地点和深度对微观浮游生物进行了采样。 塔拉海洋探险队的数据已经公布，但对研究人员来说，访问、操作和分析如此大规模的资源是一个挑战。 该项目创建了一个海洋云共享（OCC），这是一个基于云的资源和存储库，允许研究人员在云中查询塔拉海洋探险数据;它还通过海洋宝盒（OTB）提供比较宏基因组工具。海洋云共享和海洋宝盒建立在与CyVerse Cyberinfrastructure，Agave Platform，OpenCloud，德州高级计算中心的计算机设施。 Ocean Cloud Commons使用基于MapReduce的算法在Hadoop大数据框架中创建比较宏基因组数据资源。 研究人员可以使用在海洋宝盒中开发的工具广泛访问OCC，并在CyVerse网络基础设施中作为应用程序实施。 具体来说，OTB工具通过CyVerse的Agave Platform和Developer API在OpenCloud中部署和计算OCC数据。 OTB工具和OCC数据资源使研究人员能够解决影响气候和生态系统功能的海洋微生物分布的全球规模问题。高级网络基础设施部的这一奖项由NSF生物科学理事会（生物基础设施部）和NSF地球科学理事会共同支持。

The Tara Oceans Expedition has provided the largest publicly available contiguous dataset available in genomics for any scientific project in the world. Using the research schooner Tara and modern sequencing and state-of-the-art imaging technologies, a multinational team of scientists sampled microscopic plankton at hundreds of sites and depths in all the major oceanic regions. The Tara Oceans Expedition data have been released, but it is a challenge for researchers to access, manipulate, and analyze such large-scale resources. This project creates an Ocean Cloud Commons (OCC), a cloud-based resource and repository allowing researchers to query the Tara Oceans Expedition Data in the cloud; it also makes available comparative metagenomic tools through the Ocean Treasure Box (OTB).The Ocean Cloud Commons and Ocean Treasure Box build upon established partnerships with organizations such as CyVerse Cyberinfrastructure, Agave Platform, OpenCloud, and computing facilities at the Texas Advanced Computing Center. The Ocean Cloud Commons uses an algorithm based on MapReduce to create a comparative metagenomics data resource in a Hadoop big data framework. The OCC can be widely accessed by researchers using tools developed in the Ocean Treasure Box and implemented as Apps in the CyVerse Cyberinfrastructure. Specifically, OTB tools deploy and compute on OCC data in OpenCloud via the Agave Platform and Developer API from CyVerse. Taken together, the OTB tools and OCC data resources enable researchers to address global-scale questions about the distribution of microbes across the sea that affect climate and ecosystem function.This award by the Advanced Cyberinfrastructure Division is jointly supported by the NSF Directorate for Biological Sciences (Division of Biological Infrastructure), and the NSF Directorate for Geosciences.