HBCU-RISE: Expanding Graduate Research, Education and Infrastructure in Nanobiomaterials and Tissue Engineering at Alabama State University

HBCU-RISE：扩大阿拉巴马州立大学纳米生物材料和组织工程的研究生研究、教育和基础设施

• 批准号: 1646729
• 负责人: Vida Dennis
• 金额: $ 99.88万
• 依托单位: Alabama State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-12-15 至 2022-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1646729&HistoricalAwards=false
• 关键词: HBCU; RISE; Expanding; Graduate; Research

The Historically Black Colleges and Universities Research Infrastructure for Science and Engineering (HBCU-RISE) activity within the Centers of Research Excellence in Science and Technology (CREST) program supports the development of research capability at HBCUs that offer doctoral degrees in science and engineering disciplines. HBCU-RISE projects have a direct connection to the long-term plans of the host department(s) and the institutional mission, and plans for expanding institutional research capacity as well as increasing the production of doctoral students in science and engineering. With support from the National Science Foundation, Alabama State University (ASU), a four-year liberal arts institution with over 89% African American students, aims to enhance the PhD program in Microbiology by expanding research resources in the area of nanobiomaterials and tissue engineering. This project has the potential to contribute significantly to the pool of minority students trained in the emerging field of nanobiomaterials and tissue engineering and significantly expand the breadth of the PhD Program in Microbiology. The proposed project will advance the mission of ASU by providing quality education to a large underrepresented minority population and increasing the number of minority students pursuing STEM degree programs and careers.The proposed research involves the development of novel 3D bioengineered skin and drug-eluting bone scaffolds that potentially could be used to treat diseased and damaged tissues. The project objectives are to: 1) expand research infrastructure by acquiring new equipment and recruiting high caliber scientists with expertise in the area of nanobiomaterials and tissue engineering; 2) provide research support to PhD students and research faculty; and 3) introduce new courses in nanobiomaterials and cell interaction, bioinstrumentation and tissue engineering. The established research infrastructure and partnerships with several research-intensive institutions will have a broader impact on ASU. This project will expand the scientific capabilities and accomplishments of ASU on issues related to NSF's mission, scientific achievement, and technological advancements.

历史上的黑人学院和大学科学与工程研究基础设施（HBCU-RISE）活动在科学和技术卓越研究中心（CREST）计划支持在HBCU提供科学和工程学科博士学位的研究能力的发展。HBCU-RISE项目与主办部门的长期计划和机构使命以及扩大机构研究能力以及增加科学和工程博士生产量的计划有直接联系。在国家科学基金会的支持下，亚拉巴马州立大学（ASU）是一所四年制文科院校，拥有超过89%的非洲裔美国学生，旨在通过扩大纳米生物材料和组织工程领域的研究资源来加强微生物学博士课程。该项目有可能为在纳米生物材料和组织工程的新兴领域接受培训的少数民族学生做出重大贡献，并显着扩大微生物学博士课程的广度。拟议的项目将推进亚利桑那州立大学的使命，为大量代表性不足的少数民族人口提供优质教育，并增加少数民族学生攻读STEM学位课程和职业的数量。拟议的研究涉及开发新型3D生物工程皮肤和药物洗脱骨支架，这些支架可能用于治疗患病和受损组织。该项目的目标是：1）通过购买新设备和招募具有纳米生物材料和组织工程领域专业知识的高素质科学家来扩大研究基础设施; 2）为博士生和研究人员提供研究支持; 3）引入纳米生物材料和细胞相互作用，生物仪器和组织工程的新课程。与几个研究密集型机构建立的研究基础设施和伙伴关系将对ASU产生更广泛的影响。该项目将扩大ASU在与NSF的使命、科学成就和技术进步有关的问题上的科学能力和成就。

项目成果

Effects of Pseudomonas aeruginosa on Microglial-Derived Extracellular Vesicle Biogenesis and Composition

• DOI: 10.3390/pathogens8040297
• 发表时间: 2019-12-01
• 期刊: PATHOGENS
• 影响因子: 3.7
• 作者: Jones, Leandra B.;Kumar, Sanjay;Matthews, Qiana L.
• 通讯作者: Matthews, Qiana L.

Prolonged Release and Functionality of Interleukin-10 Encapsulated within PLA-PEG Nanoparticles

• DOI: 10.3390/nano9081074
• 发表时间: 2019-08-01
• 期刊: NANOMATERIALS
• 影响因子: 5.3
• 作者: Duncan, Skyla A.;Dixit, Saurabh;Dennis, Vida A.
• 通讯作者: Dennis, Vida A.

Suppressors of Cytokine Signaling (SOCS)1 and SOCS3 Proteins Are Mediators of Interleukin-10 Modulation of Inflammatory Responses Induced by Chlamydia muridarum and Its Major Outer Membrane Protein (MOMP) in Mouse J774 Macrophages

• DOI: 10.1155/2020/7461742
• 发表时间: 2020-06-24
• 期刊: MEDIATORS OF INFLAMMATION
• 影响因子: 4.6
• 作者: Duncan, Skyla A.;Sahu, Rajnish;Dennis, Vida A.
• 通讯作者: Dennis, Vida A.