REU Site: Integrative Cell and Molecular Biology

REU 网站：综合细胞和分子生物学

• 批准号: 1659556
• 负责人: Michelle Whaley
• 金额: $ 33.21万
• 依托单位: University of Notre Dame
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-03-15 至 2022-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1659556&HistoricalAwards=false
• 关键词: REU; Site; Integrative; Cell; Molecular

This REU site award to the University of Notre Dame, located in South Bend, IN, will support the training of 12 students for 10 weeks during summers 2017-2019. The REU program will provide students with independent research projects within an interdisciplinary research community. Participants will formulate their research project and proposal with their mentor, speak about their work at the beginning of the summer, and present their results at the end of summer at the Summer REU Symposium. A weekly seminar program will be included to develop students' intellectual and professional skills, as well as to educate them about various career paths in biological sciences. In addition, students will attend interactive workshops on integrative research, ethics and responsible conduct of research, the publication process, scientific writing, and graduate school applications. The underlying aim of the program is to give students strong incentives for pursuing careers in research. It is anticipated that a total of 36 students, primarily from schools with limited research opportunities, will be trained in the program. They will be recruited through general and targeted approaches with partner institutions. Students will be selected based on academic record, the quality of the personal statement/cover letter, recommendation letters, a sincere desire to pursue a research career, and potential for outstanding research in cell/molecular biology. Students will learn how research is conducted, and many will present the results of their work at scientific conferences.Participant tracking data will be obtained using a background, pre-program, post-program, and alumni survey. In addition, a common web-based assessment tool used by all REU Site programs funded by the Division of Biological Infrastructure will be used to determine the effectiveness of the training program. Continued contact with each participant will take place through planning for conference presentations, encouraging students to pursue additional research, and preparation for graduate school. More information and application materials are available at http://nd.edu/~biosreu/, or by contacting the PI (Dr. Michelle Whaley, [phone], [e-mail]) or the co-PI (Dr. David Hyde, [phone], [e-mail]).

这项授予位于宾夕法尼亚州南本德的圣母大学的REU Site奖将支持2017-2019年夏季为期10周的12名学生的培训。REU计划将为学生提供跨学科研究社区内的独立研究项目。参与者将与他们的导师一起制定他们的研究项目和建议，在夏初谈论他们的工作，并在夏末在夏季REU研讨会上展示他们的成果。每周一次的研讨会计划将包括发展学生的智力和专业技能，以及教育他们关于生物科学的各种职业道路。此外，学生还将参加关于综合研究、伦理和负责任的研究行为、出版过程、科学写作和研究生院应用的互动研讨会。该计划的根本目的是给学生在研究领域追求职业生涯的强烈激励。预计共有36名学生将在该计划中接受培训，这些学生主要来自研究机会有限的学校。他们将通过与伙伴机构的一般和有针对性的办法进行招聘。学生将根据学业记录、个人陈述/求职信的质量、推荐信、追求研究事业的真诚愿望以及在细胞/分子生物学方面的杰出研究潜力来选择。学生将学习研究是如何进行的，许多人将在科学会议上展示他们的工作结果。参与者跟踪数据将通过背景、计划前、计划后和校友调查获得。此外，将使用由生物基础设施司资助的所有REU站点方案使用的通用网络评估工具来确定培训方案的有效性。通过规划会议报告、鼓励学生进行更多的研究和准备研究生院，将继续与每位参与者保持联系。欲了解更多信息和申请材料，请访问http://nd.edu/~biosreu/，，或联系国际和平组织(米歇尔·惠利博士，电话：[phone]，电子邮件：[e-mail])或联合国际组织(戴维·海德博士，电话：[phone]，电子邮件：[e-mail])。

项目成果

Synaptic-like Vesicles Facilitate Pioneer Axon Invasion

• DOI: 10.1016/j.cub.2019.06.078
• 发表时间: 2019-08
• 期刊: Current Biology
• 影响因子: 9.2
• 作者: Evan L. Nichols;Cody J. Smith

Generating intravital super-resolution movies with conventional microscopy reveals actin dynamics that construct pioneer axons

用传统显微镜生成活体超分辨率电影揭示了构建先锋轴突的肌动蛋白动力学

• DOI: 10.1242/dev.171512
• 发表时间: 2019
• 期刊: Development
• 影响因子: 4.6
• 作者: Zhang, Yide;Nichols, Evan L.;Zellmer, Abigail M.;Guldner, Ian H.;Kankel, Cody;Zhang, Siyuan;Howard, Scott S.;Smith, Cody J.
• 通讯作者: Smith, Cody J.

Pioneer axons employ Cajal’s battering ram to enter the spinal cord

先锋轴突利用卡哈尔的攻城槌进入脊髓

• 发表时间: 2019
• 期刊: Nature communications
• 影响因子: 16.6
• 作者: Nichols, Evan L.;Smith, Cody J.
• 通讯作者: Smith, Cody J.

Functional Regeneration of the Sensory Root via Axonal Invasion

• DOI: 10.1016/j.celrep.2019.12.008
• 发表时间: 2020-01-07
• 期刊: CELL REPORTS
• 影响因子: 8.8
• 作者: Nichols, Ev L.;Smith, Cody J.
• 通讯作者: Smith, Cody J.