I-Corps: Clinical diagnostics for bowel disease
I-Corps:肠道疾病的临床诊断
基本信息
- 批准号:1713220
- 负责人:
- 金额:$ 5万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-01-01 至 2017-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The broader impact/commercial potential of this I-Corps project is to improve diagnostic tests for gastrointestinal disease and to reduce healthcare costs. Digestive diseases constitute a worldwide burden on health care. Moreover, the incidence of inflammatory bowel diseases has increased in children and in adults. Current diagnostic tools, such as biopsy, are not usually available to initiate patient treatment or management; nor is it a favorable method for repeat sampling needed in such chronic conditions. Thus, lack of tools to molecularly identify disease has restricted the ability to manage gastrointestinal inflammation in both pediatric and adult patients. A molecular diagnosis can translate to better care for the patient and financial advantage for payers.This I-Corps project will examine the potential product-market fit of diagnostic biomarkers for gastrointestinal tract disorders. Accurate, rapid, and inexpensive diagnostics can make personalized management of inflammatory bowel disease accessible. A prototype of a simple and accurate diagnostic medical device for a common and devastating bowel disease in preterm infants has been developed. Customer interviews will provide an in-depth understanding and prioritization of their needs and requirements. They also will trigger an iterative evolution of the team?s business model and product design. Beyond the economic benefit of improved clinical management of patients, technology use in clinical labs, veterinary labs, and pharmaceutical development markets can be evaluated.
I-Corps项目的更广泛影响/商业潜力是改善胃肠道疾病的诊断测试并降低医疗保健成本。消化系统疾病是全世界卫生保健的负担。 此外,儿童和成人中炎症性肠病的发病率增加。目前的诊断工具,如活检,通常不能用于启动患者治疗或管理;也不是一种有利的方法,需要在这种慢性疾病的重复采样。因此,缺乏分子识别疾病的工具限制了治疗儿科和成人患者胃肠道炎症的能力。分子诊断可以转化为更好地照顾病人和经济优势的payers.This I-Corps项目将检查潜在的产品市场适合的诊断生物标志物的胃肠道疾病。准确,快速和廉价的诊断可以使炎症性肠病的个性化管理变得容易。一个简单而准确的诊断医疗设备的早产儿常见的和毁灭性的肠道疾病的原型已经开发出来。客户访谈将提供对他们的需求和要求的深入了解和优先级排序。 他们也会引发团队的迭代进化?的商业模式和产品设计。除了改善患者临床管理的经济效益外,还可以评估临床实验室、兽医实验室和药物开发市场中的技术使用。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Sunyoung Kim其他文献
Loop 5-directed Compounds Inhibit Chimeric Kinesin-5 Motors
Loop 5 定向化合物抑制嵌合驱动蛋白 5 马达
- DOI:
- 发表时间:
2010 - 期刊:
- 影响因子:4.8
- 作者:
Liqiong Liu;Sreeja Parameswaran;Jing Liu;Sunyoung Kim;E. Wojcik - 通讯作者:
E. Wojcik
Clinical practice for sarcopenia in Asia: Online survey by the Asian Working Group for Sarcopenia.
亚洲肌肉减少症的临床实践:亚洲肌肉减少症工作组的在线调查。
- DOI:
- 发表时间:
2023 - 期刊:
- 影响因子:0
- 作者:
M. Yamada;Wei‐Ju Lee;M. Akishita;Ming;L. Kang;Sunyoung Kim;J. Lim;W. Lim;Reshma Aziz Merchant;T. Ong;L. Peng;Harisd Phannarus;M. Tan;L. Tay;C. Won;J. Woo;Liang‐Kung Chen;H. Arai - 通讯作者:
H. Arai
National trends in body mass index, overweight, and obesity among adults before and during the COVID‐19 pandemic in 2009–2021: A representative longitudinal serial study in South Korea
2009-2021 年 COVID-19 大流行之前和期间成年人体重指数、超重和肥胖的全国趋势:韩国代表性纵向系列研究
- DOI:
10.1002/jmv.28958 - 发表时间:
2023 - 期刊:
- 影响因子:12.7
- 作者:
Yeji Kim;Soeun Kim;Hyeon Jin Kim;R. Kwon;Min Seo Kim;Sunyoung Kim;S. Rhee;Soo;K. Jeong;D. Yon - 通讯作者:
D. Yon
Comprehensive Geriatric Assessment for Elderly Orthopedic Inpatients Consulted by Geriatric Medicine in a Hospital
医院老年科会诊老年骨科住院患者的老年综合评估
- DOI:
10.4235/jkgs.2014.18.4.213 - 发表时间:
2014 - 期刊:
- 影响因子:0
- 作者:
GoDoh Kim;Sunyoung Kim;C. Won;H. Choi;Byung Sung Kim;Y. Cho - 通讯作者:
Y. Cho
National trends in asthma prevalence in South Korea before and during the COVID‐19 pandemic, 1998–2021
1998-2021 年 COVID-19 大流行之前和期间韩国哮喘患病率的全国趋势
- DOI:
10.1111/cea.14394 - 发表时间:
2023 - 期刊:
- 影响因子:6.1
- 作者:
Jaeyu Park;Ann Nguyen;Mafaz Kattih;Hyeon Jin Kim;Minji Kim;Myeongcheol Lee;Hojae Lee;Sunyoung Kim;Ai Koyanagi;Lee Smith;Min Seo Kim;M. Rahmati;S. Lee;Seong H Cho;D. Yon;Nikolaos G. Papadopoulos - 通讯作者:
Nikolaos G. Papadopoulos
Sunyoung Kim的其他文献
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{{ truncateString('Sunyoung Kim', 18)}}的其他基金
SBIR Phase I: Absolute protein quantitation in in vitro diagnostics for gut inflammation
SBIR 第一阶段:肠道炎症体外诊断中的绝对蛋白质定量
- 批准号:
2015077 - 财政年份:2020
- 资助金额:
$ 5万 - 项目类别:
Standard Grant
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- 批准号:31070748
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- 项目类别:面上项目
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