EAPSI: Finding Evolutionary Links and Genes in Adaptive Radiations of Gobies by Targeted Gene Capture

EAPSI：通过靶向基因捕获寻找虾虎鱼适应性辐射中的进化联系和基因

• 批准号: 1714032
• 负责人: Kendall Johnson
• 金额: $ 0.54万
• 依托单位: Johnson Kendall E
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-01 至 2018-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1714032&HistoricalAwards=false
• 关键词: EAPSI; Finding; Evolutionary; Links; Genes

Gobies comprise a very large, complex group of fishes found in nearly all aquatic ecosystems. Species in this group can serve as models for ecological and evolutionary specializations that have allowed them to radiate into many different habitats. The relationships of gobies will be examined using a new genetic technique that will also reveal the genes that enable adaptations of these species to their environments. Additionally, it will advance understanding of how organisms can change over time and radiate to fill new roles in nature. This research will be conducted in collaboration with Dr. Chenhong Li, who developed the original technique, at his laboratory in Shanghai Ocean University. Dr. Li is a leading researcher in systematics who has developed many genetic and statistical tools for the field. His laboratory has access to all equipment and technology needed for gene-capture in this project. This project will investigate the deep phylogeny of gobies within the Gobiidae using a new gene-capture method to identify signals of directional selection in protein-coding genes across a broad suite of taxa. The ability to combine the identification of loci under selection with the resolution of difficult relationships via gene capture offers unprecedented opportunity to increase the scientific community?s understanding of adaptive radiations and speciation in general. The research funded by this award will accomplish this by creating a high-resolution phylogeny of the Gobiidae using a large number of protein-coding markers obtained by target-enrichment gene capture coupled with broad taxon sampling. This award, under the East Asia and Pacific Summer Institutes program, supports summer research by a U.S. graduate student and is jointly funded by NSF and the Ministry of Science and Technology of Taiwan.

虾虎鱼是一个非常庞大、复杂的鱼类，几乎在所有水生生态系统中都有发现。该群体中的物种可以作为生态和进化专业化的模型，使它们能够辐射到许多不同的栖息地。将使用一种新的遗传技术来检查虾虎鱼的关系，该技术还将揭示使这些物种能够适应其环境的基因。此外，它将促进人们对生物体如何随着时间的推移而变化并辐射以在自然界中扮演新角色的理解。这项研究将与开发原始技术的李晨红博士在上海海洋大学的实验室合作进行。李博士是系统学领域的领先研究员，为该领域开发了许多遗传和统计工具。他的实验室拥有该项目中基因捕获所需的所有设备和技术。该项目将使用一种新的基因捕获方法来研究戈壁鱼科内虾虎鱼的深层系统发育，以识别跨广泛类群的蛋白质编码基因的定向选择信号。将选择基因座的识别与通过基因捕获解决困难关系相结合的能力为增加科学界对适应性辐射和物种形成的总体理解提供了前所未有的机会。该奖项资助的研究将通过使用通过目标富集基因捕获和广泛的分类单元采样获得的大量蛋白质编码标记来创建戈壁科的高分辨率系统发育来实现这一目标。该奖项属于东亚和太平洋地区暑期学院计划，支持美国研究生的暑期研究，由美国国家科学基金会和台湾科学技术部共同资助。