Targeted Infusion Project: Infusing Inquiry-Based Green Chemistry into Undergraduate Laboratory Courses via Silver Recycling in a Closed Loop, Multi-course Process

有针对性的注入项目：通过闭环、多课程过程中的银回收，将基于探究的绿色化学注入本科生实验室课程

• 批准号: 1719359
• 负责人: Mohamed Abdalla
• 金额: $ 39.99万
• 依托单位: Tuskegee University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1719359&HistoricalAwards=false
• 关键词: Targeted; Infusion; Project; Infusing; Inquiry

The Historically Black Colleges and Universities Undergraduate Program (HBCU-UP) through Targeted Infusion Projects supports the development, implementation, and study of evidence-based innovative models and approaches for improving the preparation and success of HBCU undergraduate students so that they may pursue STEM graduate programs and/or careers. The project at Tuskegee University seeks to improve the undergraduate chemistry experience through guided inquiry pedagogical methods, addition of new instrumentation and real-world application of green chemistry. The proposed program includes linking chemistry concepts and green chemical methods to hands-on research experiences that will stimulate students' awareness and the pursuit of scientific careers. Students will be exposed to overarching themes of green chemistry, recycling, and sustainability, as well as their impact on the world. Since Chemistry is a service department for majors in four colleges at Tuskegee University, the proposed activities' emphasis on proper waste disposal, environmental impacts, and green chemistry principles will not only have a broad institutional impact, but will have a major impact on preparing students for a global STEM workforce.The overall goal of the program is to improve Tuskegee University's chemistry laboratory curriculum and the environment through three initiatives: 1) professional development activities for teaching with a guided inquiry-based model; 2) inclusion of Green Chemistry principles throughout the chemistry laboratory curriculum; and 3) increased student hands-on access to instrumentation. The goals will be accomplished through the development of several Guided Inquiry experiments that begin from the waste stream of the general chemistry laboratory. Silver salt waste from general chemistry laboratory will be collected and purified by analytical chemistry laboratory students. The purified silver salts will be reused in general chemistry and used as catalysts in organic chemistry laboratory synthesis. Students in nanotechnology will use the recycled silver to synthesize silver nanoparticles and investigate their biological activities. These silver nanoparticles will be utilized in the biochemistry laboratories to demonstrate their antimicrobial properties. Thus, the project will be a closed loop process that involves various levels of the institution's chemistry laboratories. Two significant benefits of the proposed activity include diversification of the experiment portfolio and the reduction of laboratory waste.

历史上的黑人学院和大学本科项目（HBCU- up）通过有针对性的输液项目支持基于证据的创新模式和方法的开发、实施和研究，以提高HBCU本科生的准备和成功，使他们可以攻读STEM研究生课程和/或职业。塔斯基吉大学的项目旨在通过指导性探究教学方法、新仪器的添加和绿色化学的实际应用来改善本科化学体验。该计划包括将化学概念和绿色化学方法与实践研究经验联系起来，这将激发学生的意识和对科学事业的追求。学生将接触到绿色化学、循环利用和可持续发展的总体主题，以及它们对世界的影响。由于化学是塔斯基吉大学四个学院专业的服务部门，因此拟议的活动强调适当的废物处理，环境影响和绿色化学原则，不仅会产生广泛的机构影响，而且会对学生为全球STEM劳动力做好准备产生重大影响。该计划的总体目标是通过三个举措来改善塔斯基吉大学的化学实验室课程和环境：1)以引导探究为基础的教学模式的专业发展活动；2)在整个化学实验课程中纳入绿色化学原则；3)增加学生动手使用仪器的机会。这些目标将通过从普通化学实验室的废物流开始的几个指导性探究实验的发展来实现。来自普通化学实验室的银盐废物将由分析化学实验室的学生收集和纯化。纯化后的银盐可在普通化学中重复使用，也可作为有机化学实验室合成的催化剂。纳米技术专业的学生将使用回收的银合成纳米银并研究它们的生物活性。这些银纳米粒子将被用于生物化学实验室，以证明它们的抗菌性能。因此，该项目将是一个闭环过程，涉及该机构的各级化学实验室。拟议活动的两个重要好处包括实验组合的多样化和减少实验室浪费。

项目成果

Combined Guided and Open Inquiry Project for an Upper Division Biochemistry Lab: Sugar Content, Enzymatic Properties of Lactase, and the Spoiling Process in Milk

• DOI: 10.1021/acs.jchemed.9b00926
• 发表时间: 2020-05-12
• 期刊: JOURNAL OF CHEMICAL EDUCATION
• 影响因子: 3
• 作者: Redden, Alexis M. Vroom;Barton, Callie M.;Willian, Kyle R.
• 通讯作者: Willian, Kyle R.