Control of Protein Attachment and its Optical Detection

蛋白质附着控制及其光学检测

• 批准号: DP0881806
• 负责人: Prof David McKenzie
• 金额: $ 59.09万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-02-21 至 2013-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0881806
• 关键词: Control; Protein; Attachment; its; Optical

Protein array technologies have applications in the rapid diagnosis of disease. Biosensors can detect traces of biohazards. Before widespread implementation of these technologies can occur however, a rapid, sensitive and convenient readout method for the control and readout of attachment of proteins to antibodies is needed. I will use electric fields, combined with array imaging at surface plasmon resonance to achieve this aim. This protein diagnostic array technology will enable accurate and rapid diagnosis of disease, generating savings on health costs and improving public health. Manufacture in Australia will bring further economic benefits.

蛋白质阵列技术可用于疾病的快速诊断。生物传感器可以检测到生物危害的痕迹。然而，在广泛实施这些技术之前，需要一种快速、灵敏和方便的读出方法来控制和读出蛋白质与抗体的连接。我将使用电场，结合表面等离子体共振阵列成像来实现这一目标。这种蛋白质诊断阵列技术将能够准确和快速地诊断疾病，节省医疗费用并改善公众健康。在澳大利亚生产将带来进一步的经济效益。