REU Site: Networked Projects in Cell and Molecular Biology at the Wadsworth Center

REU 站点：沃兹沃斯中心细胞和分子生物学网络项目

• 批准号: 1757170
• 负责人: Jon Paczkowski
• 金额: $ 28.59万
• 依托单位: Health Research Incorporated/New York State Department of Health
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-03-15 至 2023-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1757170&HistoricalAwards=false
• 关键词: REU; Site; Networked; Projects; Cell

This REU site award to the Wadsworth Center, located in Albany, NY, will support the training of 10 students for 10 weeks during the summers of 2018-2020. The primary objective of the program is to provide cutting-edge research experiences in fundamental cell and molecular biosciences, and includes projects in which undergraduate students work with each other and/or with pairs of mentor(s) on collaborative projects. Projects encompass a wide spectrum in cutting edge research in molecular genetics, cell biology, and structural and computational biology. Students will attend weekly seminars on topics including current faculty research, career options and strategies, and ethics and the responsible conduct of research. Program outcomes will be assessed based on student surveys and using the CIMER REU tool as a common assessment tool. Applications are completed online (https://www.wadsworth.org/education/undergraduate/reu), and are especially encouraged from students attending small colleges or universities, and from underrepresented minority populations. Selection of participants is made from all applications received by a committee of Wadsworth Center scientists based on personal statements from the applicant, letters of support, and transcripts of grades and courses.It is anticipated that a total of 30 students, primarily from schools with limited research opportunities, will be trained in the program. Applicants from community colleges and small colleges in New York with limited research opportunities, as well as NYS-CSTEP institutions, are encouraged to apply. Students will learn how research is conducted, and many will present the results of their work at scientific conferences. A common web-based assessment tool used by all REU Site programs funded by the Division of Biological Infrastructure will be used to determine the effectiveness of the training program. For purposes of data analysis with past records, students will also be asked to complete a second web-based assessment tool for which data has been collected for several years. Students will be tracked after the program in order to determine their career paths. Students will be asked to respond to an automatic email sent via the NSF reporting system. More information about the program is available by visiting https://www.wadsworth.org/reu, or by contacting the PI, Dr. Randall Morse, or the Program Director, Dr. Matthew Kohn, at [e-mail] award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个REU网站奖给沃兹沃斯中心，位于纽约州奥尔巴尼，将支持10名学生在2018年至2020年的夏天10周的培训。该计划的主要目标是提供基础细胞和分子生物科学的前沿研究经验，包括本科生相互合作和/或与成对导师合作的项目。项目涵盖了分子遗传学，细胞生物学以及结构和计算生物学的前沿研究。学生将参加每周一次的研讨会，主题包括当前的教师研究，职业选择和战略，道德和负责任的研究行为。计划成果将根据学生调查进行评估，并使用CIMEREU工具作为通用评估工具。申请在网上完成（https：//www.wadsoft.org/education/undergraduate/reu），特别鼓励就读于小型学院或大学的学生以及代表性不足的少数民族。参与者的选择是从收到的所有申请由沃兹沃斯中心的科学家委员会的基础上从申请人的个人陈述，支持信，成绩单和courses.It预计，总共30名学生，主要来自学校的研究机会有限，将在该计划中进行培训。鼓励来自纽约研究机会有限的社区学院和小型学院以及NYS-CSTEP机构的申请人申请。学生将学习如何进行研究，许多人将在科学会议上展示他们的工作成果。由生物基础设施部资助的所有REU研究中心项目使用的通用网络评估工具将用于确定培训项目的有效性。为了对过去的记录进行数据分析，学生还将被要求完成第二个基于网络的评估工具，该工具的数据已经收集了几年。学生将在课程结束后进行跟踪，以确定他们的职业道路。学生将被要求通过NSF报告系统自动发送电子邮件。有关该计划的更多信息，请访问https：//www.wadsoft.org/reu，或联系PI，Dr. Randall莫尔斯，或项目主任，Dr. Matthew Kohn，[e-mail]。该奖项反映了NSF的法定使命，并已被认为值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估来支持。

项目成果

Mycobacterial HflX is a ribosome splitting factor that mediates antibiotic resistance

• DOI: 10.1073/pnas.1906748117
• 发表时间: 2019-12
• 期刊: Proceedings of the National Academy of Sciences
• 作者: Paulami Rudra;Kelley R. Hurst-Hess;Katherine L. Cotten;Andrea Partida-Miranda;P. Ghosh

Force balances between interphase centrosomes as revealed by laser ablation

激光烧蚀揭示间期中心体之间的力平衡

• DOI: 10.1091/mbc.e19-01-0034
• 发表时间: 2019
• 期刊: Molecular Biology of the Cell
• 影响因子: 3.3
• 作者: Odell, Jacob;Sikirzhytski, Vitali;Tikhonenko, Irina;Cobani, Sonila;Khodjakov, Alexey;Koonce, Michael;Chang, Fred
• 通讯作者: Chang, Fred

Blood treatment of Lyme borreliae demonstrates the mechanism of CspZ-mediated complement evasion to promote systemic infection in vertebrate hosts

莱姆疏螺旋体的血液处理证明了 CspZ 介导的补体逃逸促进脊椎动物宿主全身感染的机制

• DOI: 10.1111/cmi.12998
• 发表时间: 2019
• 期刊: Cellular Microbiology
• 影响因子: 3.4
• 作者: Marcinkiewicz, Ashley L.;Dupuis, Alan P.;Zamba-Campero, Maxime;Nowak, Nancy;Kraiczy, Peter;Ram, Sanjay;Kramer, Laura D.;Lin, Yi-Pin
• 通讯作者: Lin, Yi-Pin