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Diagnosing Urban Stream Syndrome: Identifying Novel Contaminants and Toxicants in Our Stormwater

诊断城市河流综合症：识别雨水中的新型污染物和有毒物质

基本信息

批准号：
1803240
负责人：
Edward Kolodziej
金额：
$ 32.96万
依托单位：
University of Washington
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-15 至 2023-02-28
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1803240&HistoricalAwards=false
关键词：
Diagnosing Urban Stream Syndrome Identifying

项目摘要

In rapidly urbanizing areas of the Unites States, stormwater runoff is a major water quality and treatment problem because it accumulates many harmful chemicals from our homes, roads, and cities as it flows downstream. Although it this "urban stream syndrome" is known to be harmful to fish and aquatic ecosystems, the chemical make-up of urban stormwater runoff is poorly understood. This project will focus on identifying toxic chemicals in urban stormwater, focusing particularly on understanding the link between stormwater pollution and observations of mortality in the economically and culturally important adult coho salmon in the Pacific Northwest. This project will measure harmful pollutants in stormwater with the goal to better manage urban water quality and protect fish such as coho salmon. Citizen scientists will help monitor watersheds for salmon mortality as it happens, and alert project researchers to collect water and tissue samples during acute mortality events. The research group of Edward Kolodziej will work with citizen science groups, regional agencies, and the Center for Urban Waters (Tacoma, WA) to collaborate with local, regional, state, and tribal communities who are interested in protecting salmon for economic and cultural reasons. Relative to well-studied urban pollutant sources such as municipal wastewater effluent, little is known about the chemical composition of urban stormwater runoff despite its importance as a major source of chemical pollutants to receiving waters. In the Pacific Northwest, an unexplained acute mortality phenomena occurs widely in urbanized watersheds where 50-100% of adult coho salmon quickly perish after urban stormwater exposure. This project will focus on characterizing the identity and quantity of novel contaminants in urban stormwater using high-resolution mass spectrometry to identify stormwater contaminants with problematic structures such as metabolic poisons that inhibit mitochondrial electron transport and induce cellular hypoxia. Water and tissue samples collected by citizen scientists will be screened using broad spectrum, suspect and non-target analyses to identify novel pollutants in urban stormwater. Chemical bioactivity will be selectively screened via in-silico receptor docking to detect novel bioactivity from high interest detections. Along with ongoing ecotoxicology efforts, selective fractionation and chemical screening will be used to identify toxicant candidates in toxicologically active samples and link toxicant chemical characteristics to typical stormwater runoff treatment systems. Project outputs will be broadly disseminated through collaboration and outreach efforts to local and regional citizen science programs. Through the project affiliation with the Center for Urban Waters, additional outreach to local, regional, state, and tribal stakeholders, many of them very interested in salmonid health for economic and cultural reasons, will occur. Project collaborations will include regional municipalities and agencies such as the Puget Sound Partnership as well as NOAA-NMFS researchers and regulators focused on the health of economically important salmon populations. Via project characterization efforts, the management of urban stormwater quality can be improved by enhanced capabilities for chemical source control and optimization of treatment technologies.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在美国快速城市化的地区，雨水径流是一个主要的水质和处理问题，因为它在向下游流动时会从我们的家庭、道路和城市中积累许多有害化学物质。尽管众所周知，这种“城市河流综合症”对鱼类和水生生态系统有害，但人们对城市雨水径流的化学组成知之甚少。该项目将侧重于识别城市雨水中的有毒化学物质，特别侧重于了解雨水污染与观察太平洋西北部具有重要经济和文化意义的成年Coho鲑鱼死亡率之间的联系。该项目将测量雨水中的有害污染物，目的是更好地管理城市水质，保护鱼类，如大马哈鱼。公民科学家将帮助监测发生时三文鱼死亡的分水岭，并提醒项目研究人员在急性死亡事件期间收集水和组织样本。Edward Kolodziej的研究小组将与公民科学团体、地区机构和城市水域中心(华盛顿州塔科马)合作，与出于经济和文化原因对保护鲑鱼感兴趣的地方、地区、州和部落社区合作。相对于城市污水等已被充分研究的城市污染源，人们对城市雨水径流的化学成分知之甚少，尽管它是接收水体化学污染物的主要来源。在太平洋西北部，城市化集水区普遍存在一种无法解释的急性死亡现象，那里50%-100%的成年鳕鱼在城市暴雨暴露后迅速死亡。该项目将专注于使用高分辨率质谱仪来表征城市雨水中新污染物的身份和数量，以识别具有问题结构的雨水污染物，例如抑制线粒体电子传递和诱导细胞缺氧的代谢毒物。公民科学家收集的水和组织样本将使用广谱、可疑和非目标分析进行筛选，以识别城市雨水中的新污染物。化学生物活性将通过电子受体对接选择性地进行筛选，以从高兴趣的检测中检测新的生物活性。除了正在进行的生态毒理学工作外，还将使用选择性分馏和化学筛选来确定毒理活性样本中的有毒候选物质，并将有毒化学特征与典型的雨水径流处理系统联系起来。项目成果将通过与当地和地区公民科学项目的合作和推广工作广泛传播。通过与城市水域中心的项目合作，将与地方、地区、州和部落利益攸关方进行更多的接触，其中许多人出于经济和文化原因对鲑鱼健康非常感兴趣。项目合作将包括区域市政当局和机构，如普吉特湾伙伴关系，以及NOAA-NMFS研究人员和监管机构，重点关注经济上重要的鲑鱼种群的健康。通过项目鉴定工作，城市雨水质量的管理可以通过增强化学源控制和优化处理技术的能力来改善。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

期刊论文数量（7）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Transformation Products of Tire Rubber Antioxidant 6PPD in Heterogeneous Gas-Phase Ozonation: Identification and Environmental Occurrence

轮胎橡胶防老剂6PPD在非均相气相臭氧氧化中的转化产物：鉴定及环境发生

DOI：
10.1021/acs.est.2c08690
发表时间：
2023
期刊：
Environmental Science & Technology
影响因子：
11.4
作者：
Zhao, Haoqi Nina;Hu, Ximin;Tian, Zhenyu;Gonzalez, Melissa;Rideout, Craig A.;Peter, Katherine T.;Dodd, Michael C.;Kolodziej, Edward P.
通讯作者：
Kolodziej, Edward P.

Characterizing the Chemical Profile of Biological Decline in Stormwater-Impacted Urban Watersheds

DOI：
10.1021/acs.est.1c08274
发表时间：
2022-03-01
期刊：
ENVIRONMENTAL SCIENCE & TECHNOLOGY
影响因子：
11.4
作者：
Peter, Katherine T.;Lundin, Jessica, I;Kolodziej, Edward P.
通讯作者：
Kolodziej, Edward P.

Chemical characteristics, leaching, and stability of the ubiquitous tire rubber-derived toxicant 6PPD-quinone

普遍存在的轮胎橡胶毒物 6PPD-醌的化学特性、浸出和稳定性

DOI：
10.1039/d3em00047h
发表时间：
2023
期刊：
Environmental Science: Processes & Impacts
影响因子：
0
作者：
Hu, Ximin;Zhao, Haoqi;Tian, Zhenyu;Peter, Katherine T.;Dodd, Michael C.;Kolodziej, Edward P.
通讯作者：
Kolodziej, Edward P.

6PPD-Quinone: Revised Toxicity Assessment and Quantification with a Commercial Standard

DOI：
10.1021/acs.estlett.1c00910
发表时间：
2022-01-11
期刊：
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
影响因子：
10.9
作者：
Tian, Zhenyu;Gonzalez, Melissa;Kolodziej, Edward P.
通讯作者：
Kolodziej, Edward P.

Screening p -Phenylenediamine Antioxidants, Their Transformation Products, and Industrial Chemical Additives in Crumb Rubber and Elastomeric Consumer Products

筛选粒状橡胶和弹性消费品中的对苯二胺抗氧化剂、其转化产物以及工业化学添加剂

DOI：
10.1021/acs.est.2c07014
发表时间：
2023
期刊：
Environmental Science & Technology
影响因子：
11.4
作者：
Zhao, Haoqi Nina;Hu, Ximin;Gonzalez, Melissa;Rideout, Craig A.;Hobby, Grant C.;Fisher, Matthew F.;McCormick, Carter J.;Dodd, Michael C.;Kim, Kelly E.;Tian, Zhenyu
通讯作者：
Tian, Zhenyu