MRI: Acquisition of an Atomic Force Microscope for Materials Research and Education

MRI:购买原子力显微镜用于材料研究和教育

基本信息

  • 批准号:
    1828232
  • 负责人:
  • 金额:
    $ 31.49万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2018
  • 资助国家:
    美国
  • 起止时间:
    2018-10-01 至 2020-09-30
  • 项目状态:
    已结题

项目摘要

Non-Technical DescriptionThis Major Research Instrumentation award supports the University of Alabama at Birmingham to acquire an atomic force microscope for interdisciplinary materials research and education. This microscope supports a diverse, multi-departmental research in soft materials ranging from soft synthetic hydrogels to relatively dense composites and biological structures. The instrument provides enhanced capabilities for quantitative nanoscale mapping of electrical, mechanical, biological, and chemical properties. It also plays a vital role in student education in the fields of chemistry, materials science, biomedical science and biomedical engineering. Educational opportunities are available not only for undergraduates, graduate students, and postdoctoral fellows on the campus, but they expand via outreach to local middle and high school students. These multidisciplinary educational efforts are important to increase the recognition of the research efforts in the Departments of Chemistry, Medicine, and Biomedical Engineering in order to improve student recruiting, especially among underrepresented populations. A high caliber research environment is also vital to the regional economy in Central Alabama through raising community awareness toward biomedical and soft-materials technologies.Technical DescriptionThis atomic force microscope combines the capabilities for high-resolution and high-speed imaging with quantitative nano-electrical and nanomechanical mapping. The ability to acquire multifunctional, high-resolution data under a wide range of operating conditions allows for studies on a broad spectrum of dry and hydrated samples. The types of samples extend from synthetic networks, polymer composites, nanodevices, to cell membranes and tissues. The common theme among these samples is that they all involve soft materials, i.e., synthetic polymers, biological structures, or combinations of the two. An increased ability to characterize state-of-the-art nanomaterials results in an enhanced fundamental understanding of the structural properties of soft materials and the composition at their surfaces. This includes the effect of the surface morphology on the physical, biological, and chemical characteristics of the materials. The understanding enables transformative research for the development of new materials in tissue regenerative therapies, controlled drug delivery, molecular sensing, and related biotechnologies.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
非技术描述这个主要的研究仪器奖支持伯明翰的亚拉巴马大学获得跨学科材料研究和教育的原子力显微镜。该显微镜支持软材料的多样化,多部门研究,从软合成水凝胶到相对致密的复合材料和生物结构。该仪器提供了增强的能力,定量纳米级映射的电气,机械,生物和化学性质。它还在化学,材料科学,生物医学科学和生物医学工程领域的学生教育中发挥着至关重要的作用。教育机会不仅适用于校园内的本科生,研究生和博士后研究员,而且还通过与当地初中和高中学生的联系扩大。这些多学科的教育工作是重要的,以提高在化学,医学和生物医学工程部门的研究工作的认可,以提高学生的招聘,特别是在代表性不足的人口。一个高素质的研究环境也是至关重要的区域经济在中部亚拉巴马通过提高社区意识对生物医学和软材料technology.Technical Description这原子力显微镜相结合的能力,高分辨率和高速成像与定量纳米电子和纳米力学映射。在广泛的操作条件下获得多功能,高分辨率数据的能力允许对广泛的干燥和水合样品进行研究。样品的类型从合成网络、聚合物复合材料、纳米器件到细胞膜和组织。这些样品中的共同主题是它们都涉及软材料,即,合成聚合物、生物结构或两者的组合。提高表征最先进纳米材料的能力,可以增强对软材料结构特性及其表面组成的基本理解。这包括表面形态对材料的物理、生物和化学特性的影响。该奖项反映了NSF的法定使命,并通过使用基金会的知识价值和更广泛的影响审查标准进行评估,被认为值得支持。

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Photocatalytic Nanocomposite Microsponges of Polylactide–Titania for Chemical Remediation in Water
  • DOI:
    10.1021/acsapm.0c00937
  • 发表时间:
    2020-10
  • 期刊:
  • 影响因子:
    3.9
  • 作者:
    Nirzari Gupta;V. Kozlovskaya;Maksim Dolmat;Benjamin Yancey;Jonghwa Oh;C. Lungu;E. Kharlampieva
  • 通讯作者:
    Nirzari Gupta;V. Kozlovskaya;Maksim Dolmat;Benjamin Yancey;Jonghwa Oh;C. Lungu;E. Kharlampieva
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Eugenia Kharlampieva其他文献

Direct Radiolabeling of Trastuzumab-Targeting Triblock Copolymer Vesicles with sup89/supZr for Positron Emission Tomography Imaging
用 sup89/supZr 对靶向曲妥珠单抗的三嵌段共聚物囊泡进行直接放射性标记用于正电子发射断层扫描成像
  • DOI:
    10.1021/acs.biomac.2c01539
  • 发表时间:
    2023-04-10
  • 期刊:
  • 影响因子:
    5.400
  • 作者:
    Veronika Kozlovskaya;Maxwell Ducharme;Maksim Dolmat;James M. Omweri;Volkan Tekin;Suzanne E. Lapi;Eugenia Kharlampieva
  • 通讯作者:
    Eugenia Kharlampieva
Unmasked by stretching
通过拉伸而显露出来
  • DOI:
    10.1038/nmat2523
  • 发表时间:
    2009-09-01
  • 期刊:
  • 影响因子:
    38.500
  • 作者:
    Eugenia Kharlampieva;Vladimir V. Tsukruk
  • 通讯作者:
    Vladimir V. Tsukruk
Polymer vesicles for the delivery of inhibitors of cariogenic biofilm
  • DOI:
    10.1016/j.dental.2024.09.006
  • 发表时间:
    2024-11-01
  • 期刊:
  • 影响因子:
  • 作者:
    Parmanand Ahirwar;Veronika Kozlovskaya;Piyasuda Pukkanasut;Pavel Nikishau;Sarah Nealy;Gregory Harber;Suzanne M. Michalek;Linto Antony;Hui Wu;Eugenia Kharlampieva;Sadanandan E. Velu
  • 通讯作者:
    Sadanandan E. Velu

Eugenia Kharlampieva的其他文献

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{{ truncateString('Eugenia Kharlampieva', 18)}}的其他基金

Symposium Support for the 259th American Chemical Society National Meeting, March 22-26, 2020, Philadelphia, PA
第 259 届美国化学会全国会议研讨会支持,2020 年 3 月 22-26 日,宾夕法尼亚州费城
  • 批准号:
    1939807
  • 财政年份:
    2019
  • 资助金额:
    $ 31.49万
  • 项目类别:
    Standard Grant
Dampening autoimmunity with encapsulated autoantigens in polyphenolic capsules
用多酚胶囊中封装的自身抗原抑制自身免疫
  • 批准号:
    1608728
  • 财政年份:
    2016
  • 资助金额:
    $ 31.49万
  • 项目类别:
    Standard Grant
Symposium Support for the 252nd American Chemical Society National Meeting: Soft Material Surface Modification to Control Cell/Surface Interactions
第 252 届美国化学会全国会议研讨会支持:软材料表面改性控制细胞/表面相互作用
  • 批准号:
    1636755
  • 财政年份:
    2016
  • 资助金额:
    $ 31.49万
  • 项目类别:
    Standard Grant
CAREER: Shape Responses of Ultrathin Hydrogel Microcapsules
职业:超薄水凝胶微胶囊的形状响应
  • 批准号:
    1350370
  • 财政年份:
    2014
  • 资助金额:
    $ 31.49万
  • 项目类别:
    Continuing Grant
Immunomodulatory ultrathin coatings for pancreatic islet transplantation
用于胰岛移植的免疫调节超薄涂层
  • 批准号:
    1306110
  • 财政年份:
    2013
  • 资助金额:
    $ 31.49万
  • 项目类别:
    Continuing Grant

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