A Mathematical Model of the Roles of Contraction and Oxygen in Human Wound Healing

缓慢或受损的伤口愈合和与烧伤相关的过多疤痕既痛苦又昂贵。此外，随着人口的持续老龄化和目前2型糖尿病发病率的上升，慢性伤口的衰弱效应可能会增加。该项目汇集了一个多学科团队，开发人体伤口愈合的数学模型，并推动该模型在基础科学水平上产生重要突破，对实验学家和临床医生都有影响。

Slow or impaired wound healing and excessive scarring associated with burns are both painful and costly. Moreover, the debilitating effect of chronic wounds can be expected to increase with the continuing aging of the population and the current rise in incidence of Type 2 diabetes. This project brings together a multidisciplinary team to develop a mathematical model of human wound healing and to drive the modelling to generate important breakthroughs at the level of basic science with implications for both experimentalists and clinicians.