NSF Postdoctoral Fellowship in Biology FY 2019: Population genomics of elevational range limits in Andean birds

2019 财年 NSF 生物学博士后奖学金：安第斯鸟类海拔范围限制的种群基因组学

• 批准号: 1907353
• 负责人: Ethan Linck
• 金额: $ 13.8万
• 依托单位: Linck, Ethan B
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-01 至 2023-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1907353&HistoricalAwards=false
• 关键词: NSF; Postdoctoral; Fellowship; Biology; FY

This action funds an NSF Postdoctoral Research Fellowship in Biology for FY 2019, Research Using Biological Collections. The fellowship supports research and training of the fellow that will utilize biological collections in innovative ways. All species occur within a limited area known as their geographic range. Range limits can form without an obvious physical barrier because competition with other species prevents further expansion, because they are unable to adapt to a new environment, or because there are too few individuals of the same species to reproduce effectively. Many tropical organisms have narrow elevational ranges, meaning they occur only for a short vertical distance on continuous mountain slopes. This allows many species to coexist in a small area, and is part of why the tropics have so many species. However, we know relatively little about what determines elevational ranges in the tropics. The fellow will use DNA sequence data from extensive museum collections of Andean birds to understand the role of evolutionary and ecological processes in forming range limits. By understanding how these processes interact, we can better predict how species will respond to human induced environmental change. This has broad implications for biodiversity conservation and human health as endangered species and new diseases experience a warming world. The fellow will evaluate alternate hypotheses for species range limits by comparing the spatial distribution of genetic variation of tropical songbird species that have either narrow (1500 m) or broad (3000 m) elevational ranges. Using dense geographic sampling in extant biological collections from the Peruvian Andes, he will generate genome-wide DNA sequence data from across the full elevational ranges of 8 phylogenetically independent lineages. Each lineage will contain both elevational specialist and elevational generalist species. He will first use these data to identify the evolutionary and ecological processes that determine elevational ranges in Andean birds. Comparing observed patterns with predictions validated by simulations, he will evaluate the relative contribution of decreasing effective population size, biotic interactions, and migration from maladapted populations to the formation of equilibrium range limits. He will then test whether functional variation in hemoglobin is a prerequisite for elevational range expansion, and characterize whether adaptive variants have undergone hard or soft selective sweeps. During his postdoctoral research, the fellow will undergo training in museum curation and biodiversity informatics, advanced statistical genomics, and functional genetics. The research will be based at University of New Mexico, a majority-minority R1 institution, where the fellow will serve as a mentor in a training program for underrepresented students interested in research careers.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该行动为使用生物收集的研究基金为2019财年的生物学生物学奖学金提供了资金。奖学金支持将以创新的方式利用生物收藏的研究员的研究和培训。所有物种都发生在有限区域内，称为其地理范围。范围限制可以在没有明显的物理障碍的情况下形成，因为与其他物种的竞争会阻止进一步的扩展，因为它们无法适应新的环境，或者因为相同物种的个体太少而无法有效地繁殖。许多热带生物具有狭窄的海拔范围，这意味着它们仅在连续的山坡上发生短垂直距离。这使许多物种可以在一个小区域共存，这是热带地区如此多物种的一部分。但是，我们对在热带地区的提升范围的确定范围相对较少。该研究员将使用广泛的博物馆收集的DNA序列数据来了解进化和生态过程在形成范围限制中的作用。通过了解这些过程的相互作用，我们可以更好地预测物种将如何应对人类诱发的环境变化。随着濒危物种和新疾病经历着温暖的世界，这对生物多样性保护和人类健康具有广泛的影响。该研究员将通过比较具有狭窄（1500 m）或宽（3000 m）高度范围的热带鸣鸟物种的遗传变异的空间分布来评估物种范围限制的替代假设。在秘鲁安第斯山脉的现有生物收集中，使用密集的地理采样，他将从8个系统发育独立的谱系的整个海拔高度范围内产生全基因组DNA序列数据。每个血统将既包含海拔专家和高度通才物种。他将首先使用这些数据来确定确定安第斯鸟类高度范围的进化和生态过程。将观察到的模式与通过模拟验证的预测进行比较，他将评估有效种群大小，生物相互作用以及从不良群体种群迁移到平衡范围限制的形成的相对贡献。然后，他将测试血红蛋白的功能变化是高程范围扩展的先决条件，并表征自适应变体是否经历过硬选择性或软选择性扫描。在他的博士后研究中，该研究员将接受博物馆策展和生物多样性信息学，高级统计基因组学和功能遗传学的培训。这项研究将位于新墨西哥大学，这是大多数R1机构，该研究员将在该研究人员中担任对研究职业感兴趣的人数不足的学生的培训计划的导师。该奖项反映了NSF的法定任务，并认为通过基金会的知识分子和更广泛的影响，可以通过评估来进行评估。

项目成果

Blood variation implicates respiratory limits on elevational ranges of Andean birds

• DOI: 10.1086/723222
• 发表时间: 2021-10
• 期刊: bioRxiv
• 作者: E. Linck;J. Williamson;Emil Bautista;Elizabeth J. Beckman;Phred M. Benham;S. DuBay;L. Flores;Chauncey R. Gadek;A. Johnson;Matthew R. Jones;Jano Núñez-Zapata;Alessandra Quiñonez;C. J. Schmitt;D. Susanibar;Tiravanti C. Jorge;K. Verde-Guerra;N. A. Wright;T. Valqui;J. F. Storz;C. Witt

Evolutionary conservatism will limit responses to climate change in the tropics

• DOI: 10.1098/rsbl.2021.0363
• 发表时间: 2021-10-06
• 期刊: BIOLOGY LETTERS
• 影响因子: 3.3
• 作者: Linck, Ethan B.;Freeman, Benjamin G.;Ghalambor, Cameron K.
• 通讯作者: Ghalambor, Cameron K.