Periimplantitis and soft-tissue defects of dental implants: A pilot study on the fixing of the suprastructure as a possible factor affecting aetiology
牙种植体的种植体周围炎和软组织缺陷:上部结构固定作为影响病因的可能因素的初步研究
基本信息
- 批准号:237797147
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:德国
- 项目类别:Research Grants
- 财政年份:2013
- 资助国家:德国
- 起止时间:2012-12-31 至 2014-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Inflammatory destruction of the periimplant bone (periimplantitis) is the most common reason for late implant loss. For implants supporting cemented suprastructures, a possible reason is the presence of undetected excess cement in the periimplant soft tissue, especially when standard abutments are used, when the cement gap is subgingival. Individual abutments might not face this problem, because the cement cap can be constructed so it is cleanable, but no data are yet available. This pilot-study will be conducted on 20 patients, comparing standard and individual abutments. The primary endpoint of the pilot study is to quantify undetected excess cement on standard and individual abutments and in the soft tissue around the implants with implant-supported single crowns after two weeks within an exploratory examination. For each abutment, 4 measurement points will be examined (buccal, lingual, distal, mesial). Position and distribution of the ratios of cement-free surface and surface with undetected excess cement will be shown as mean and standard deviation and displayed as box-plots. In addition, the periimplant soft tissue will be examined for volumetric changes or signs of inflammation, and cases of loss of retention will also be documented. All working steps in fabrication of the implant-supported single crowns will be performed by one dentist and one dental technician only. To avoid bias, randomization will be performed and all investigations in the study will be performed by two calibrated investigators who did not participate in the dental treatment at any time. The Institute of Medical Biometry and Informatics (IMBI) of the University of Heidelberg will be involved in the study from planning to statistical analysis. The aetiology of periimplantitis is numerous and mostly unknown, and the incidence is increasing drastically. This pilot study will enable calculation of sample size for a main study, which will be a multicentre study performed at the Universities of Frankfurt and Heidelberg, and within the existing practice network also, to emphasize the clinical relevance of this investigation. The purpose of the main study will be to formulate recommendations for treatment which enable undetected excess cement in the peri-implant soft tissue, a possible aetiological factor of periimplantitis, to be avoided.
种植体周围骨的炎性破坏(种植体周围炎)是晚期种植体丢失的最常见原因。对于支持骨水泥型上部结构的种植体,一个可能的原因是种植体周围软组织中存在未检测到的多余骨水泥,特别是当使用标准基台时,当骨水泥间隙位于龈下时。个别基台可能不会面临这个问题,因为水泥帽可以建造,所以它是可清洁的,但没有数据可用。将对20名患者进行这项初步研究,比较标准基台和个体基台。初步研究的主要终点是在探索性检查中,量化两周后标准和个体基台上以及种植体支持单冠种植体周围软组织中未检测到的多余骨水泥。对于每个基台,将检查4个测量点(颊侧、舌侧、远中、近中)。无骨水泥表面和未检测到过量骨水泥的表面的位置和比例分布将显示为平均值和标准差,并显示为箱形图。此外,将检查种植体周围软组织的体积变化或炎症体征,还将记录固位丧失的病例。种植体支持的单冠制造的所有工作步骤将仅由一名牙医和一名牙科技师执行。为避免偏倚,将进行随机化,研究中的所有调查将由两名在任何时间均未参与牙科治疗的校准研究者进行。海德堡大学医学生物统计学和信息学研究所(IMBI)将参与从计划到统计分析的研究。种植体周围炎的病因很多,大多数是未知的,发病率急剧增加。本初步研究将能够计算主研究的样本量,主研究将是在法兰克福大学和海德堡大学以及现有实践网络内进行的多中心研究,以强调本研究的临床相关性。主要研究的目的是制定治疗建议,以避免种植体周围软组织中未检测到的过量骨水泥,这是种植体周围炎的可能病因。
项目成果
期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Undetected residual cement on standard or individualized all-ceramic abutments with cemented zirconia single crowns - a prospective randomized pilot trial.
标准或个性化全瓷基台上未检测到的带有氧化锆单冠骨水泥的残留水泥——一项前瞻性随机试验
- DOI:10.1111/clr.12691
- 发表时间:2016
- 期刊:
- 影响因子:4.3
- 作者:Kappel S;Eiffler C;Lorenzo JB;Stober T;Rammelsberg P
- 通讯作者:Rammelsberg P
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Privatdozentin Dr. Stefanie Kappel其他文献
Privatdozentin Dr. Stefanie Kappel的其他文献
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