Deciphering Interactions Among Marine Introduced Parasites and Native Hosts

破译海洋引入的寄生虫和本地宿主之间的相互作用

基本信息

  • 批准号:
    1924623
  • 负责人:
  • 金额:
    $ 56.97万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-09-01 至 2024-08-31
  • 项目状态:
    已结题

项目摘要

The world's oceans become more connected through increased global transportation. This transportation has brought organisms to places where they were previously not found. Some of them become invasive and disrupt native marine habitats. Among these invasive species, parasites are particularly troublesome. They are usually small, easily overlooked, and can cause mass mortality of native species. Despite the serious negative impacts of marine invasive parasites, scientists still lack an in-depth understanding of mechanisms that enable them to successfully establish themselves in a new habitat. This project will study three major questions regarding marine invasive parasites' establishment: (1) How do parasites recognize new hosts when arriving at a new habitat? (2) Why can invasive parasites spread so fast to new hosts? (3) How do new host populations maintain viability despite heavy parasite infestation? This study system is the native blue mud shrimp from the Pacific coast of North America; a blood sucking parasite introduced from Asia; and the parasite's original host, the Asian mud shrimp. This project will greatly expand the knowledge of marine invasive biology and help develop effective conservation strategies to avoid unforeseen ecological disasters. A citizen science program will be established in Alaska to monitor population dynamics of the mud shrimp and the parasite. A museum-based outreach program will be established to encourage excitement about marine science in underrepresented elementary and middle school girls. In addition, graduate students, undergraduate students and high school students will participate in research to train the next generation of scientists. This proposal was co-funded by the Symbiosis, Defense and Self-recognition (SDS) program in the Integrative Organismal Systems (IOS) Division of the Biological Sciences Directorate and by the Biological Oceanography section of the Division of Ocean Sciences (OCE) of the Geosciences Directorate.To characterize interactions between the invasive bopyrid isopod parasite (Orthione griffenis) and the host shrimps (Upogebia pugettensis and Upogebia major), this research program will generate ecological, behavioral, and genetic data over the entire range of the invasion, from California to Alaska. First, metagenomics and behavioral experiments will test whether microbial cues in the host burrows play a major role in attracting parasite larval settlement, aiding the parasite's transition from Asian to North American estuaries. Second, experiments will address whether the lacking of co-evolutionary history between the new host and the parasite, or an "enemy release" for the parasite, is the main driver for the high infectious rate on the new host. The hypotheses will be tested by comparing parasite prevalence on different hosts in their old and new distribution ranges. Lastly, the double digest restriction site-associated DNA approach will be used to investigate the population genomics of the new host. The research addresses multiple-level interactions among the invasive parasite, the new host, the original host, and the marine estuarine microbial communities. Results will serve as a model of bopyrid invasion pattern, and aid the discovery and monitoring of other potential marine parasite invasions or epidemics. A citizen science program and a museum-based outreach program will be established to encourage excitement about marine science in the public. In addition, graduate students, undergraduate students and high school students will participate in research to train the next generation of scientists.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
全球运输的增加使世界各海洋的联系更加紧密。这种运输将生物带到了以前没有发现的地方,其中一些变成了入侵者,破坏了原生海洋栖息地。在这些入侵物种中,寄生虫尤其令人头疼。它们通常很小,容易被忽视,并可能导致本地物种的大规模死亡。尽管海洋入侵寄生虫造成了严重的负面影响,但科学家们仍然缺乏对使它们能够成功地在新栖息地建立自己的机制的深入了解。本计画将探讨海洋入侵寄生虫定居的三个主要问题:(1)寄生虫到达新的栖息地后,如何识别新的宿主?(2)为什么入侵性寄生虫能如此迅速地传播到新的宿主?(3)新的宿主种群如何在严重寄生虫感染的情况下保持生存能力?该研究系统是来自北美太平洋沿岸的本地蓝泥虾;从亚洲引进的吸血寄生虫;以及寄生虫的原始宿主,亚洲泥虾。该项目将大大扩展海洋入侵生物学知识,并帮助制定有效的保护战略,以避免不可预见的生态灾难。将在阿拉斯加建立一个公民科学计划,以监测泥虾和寄生虫的种群动态。将建立一个以博物馆为基础的推广计划,以鼓励代表性不足的小学和中学女生对海洋科学的兴奋。此外,研究生、本科生和高中生将参与研究,培养下一代科学家。该提案由生物科学理事会综合有机体系统司的共生、防御和自我识别方案和地球科学理事会海洋科学司的生物海洋学科共同资助。(Orangelgriffenis)和宿主虾(Upogebia pugettensis和Upogebia major),这项研究计划将产生从加州到阿拉斯加的整个入侵范围内的生态、行为和遗传数据。首先,宏基因组学和行为实验将测试宿主洞穴中的微生物线索是否在吸引寄生虫幼虫定居方面发挥重要作用,帮助寄生虫从亚洲过渡到北美河口。其次,实验将解决新宿主和寄生虫之间缺乏共同进化历史,或者寄生虫的“敌人释放”,是否是新宿主高感染率的主要驱动因素。将通过比较新旧分布范围内不同宿主的寄生虫流行率来检验假设。最后,双酶切位点相关DNA方法将用于研究新宿主的群体基因组学。 该研究涉及入侵寄生虫,新宿主,原宿主和海洋河口微生物群落之间的多层次相互作用。结果将作为牛肝菌入侵模式的模型,并有助于发现和监测其他潜在的海洋寄生虫入侵或流行病。将建立一个公民科学计划和一个以博物馆为基础的外展计划,以鼓励公众对海洋科学的兴奋。此外,研究生、本科生和高中生将参与研究,以培养下一代科学家。该奖项反映了NSF的法定使命,并通过使用基金会的智力价值和更广泛的影响审查标准进行评估,被认为值得支持。

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Co-infesting symbionts on a threatened marine host: evaluating correlations between an introduced parasitic isopod and a native symbiotic clam
受威胁海洋宿主上的共侵染共生体:评估引入的寄生等足类动物与本地共生蛤之间的相关性
  • DOI:
    10.3354/meps14105
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Li, J.;Chapman, J.;Johnson, P.
  • 通讯作者:
    Johnson, P.
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Jingchun Li其他文献

Path Loss Modification and Multi-User Capacity Analysis by Dynamic Rain Models for 5G Radio System in Millimeter Waves
毫米波 5G 无线电系统动态雨模型路径损耗修正和多用户容量分析
  • DOI:
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    1.6
  • 作者:
    Xiongwen Zhao;Qi Wang;Suiyan Geng;Yu Zhang;Jianhua Zhang;Jingchun Li
  • 通讯作者:
    Jingchun Li
Effects of trapped electrons and impurities on ion temperature gradient mode in tokamak plasmas with hollow density profiles
空心密度分布托卡马克等离子体中俘获电子和杂质对离子温度梯度模式的影响
  • DOI:
  • 发表时间:
    2020
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Jingchun Li;Jiaqi Dong;Songfen Liu
  • 通讯作者:
    Songfen Liu
Conservation Genetics of a Critically Endangered Limpet Genus and Rediscovery of an Extinct Species
极度濒危帽贝属的保护遗传学和灭绝物种的重新发现
  • DOI:
  • 发表时间:
    2011
  • 期刊:
  • 影响因子:
    3.7
  • 作者:
    D. Ó Foighil;Jingchun Li;Taehwan Lee;Paul D. Johnson;R. Evans;J. Burch
  • 通讯作者:
    J. Burch
Quantum dot microsphere laser levitated in the air
悬浮在空中的量子点微球激光
  • DOI:
  • 发表时间:
    2024
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Gui;Ruixiang Liu;Lei Wang;Jianshun Li;Jingchun Li;Xiaoting Yang;Huaibin Shen;Fengjia Fan
  • 通讯作者:
    Fengjia Fan
Nonlinear study of tearing modes and plasma flows around magnetic islands in tokamak plasmas flows around magnetic islands in tokamak plasmas
托卡马克等离子体中磁岛周围撕裂模式和等离子体流的非线性研究
  • DOI:
    10.1063/5.0013209
  • 发表时间:
    2020
  • 期刊:
  • 影响因子:
    1.6
  • 作者:
    Jizong Yang;Jingchun Li;Jiaqi Dong;Songfen Liu;Peng Shi;Yizhen Zhao;Shaoyong Chen
  • 通讯作者:
    Shaoyong Chen

Jingchun Li的其他文献

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{{ truncateString('Jingchun Li', 18)}}的其他基金

Digitization TCN: Collaborative Research: Documenting Marine Biodiversity through Digitization of Invertebrate Collections (DigIn)
数字化 TCN:合作研究:通过无脊椎动物收藏数字化记录海洋生物多样性 (DigIn)
  • 批准号:
    2001269
  • 财政年份:
    2020
  • 资助金额:
    $ 56.97万
  • 项目类别:
    Standard Grant
Digitization PEN: Invertebrates from the Rocky Mountains and Great Plains: University of Colorado Museum of Natural History expands taxonomic and geographic coverage of InvertEBase
数字化 PEN:来自落基山脉和大平原的无脊椎动物:科罗拉多大学自然历史博物馆扩大了 InvertEBase 的分类和地理覆盖范围
  • 批准号:
    2001640
  • 财政年份:
    2020
  • 资助金额:
    $ 56.97万
  • 项目类别:
    Standard Grant

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    2307324
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MSM 中直肠和尿道 STI 的临床史:表征微生物组宿主免疫相互作用以促进诊断和疫苗进展
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    2023
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  • 批准号:
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