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CAREER: Macroevolutionary Biomechanics: Integrating Morphology, Mechanical Models, and Phylogenetic Comparative Methods to Understand the Evolution of Swimming Performance in Frogs

职业：宏观进化生物力学：整合形态学、力学模型和系统发育比较方法来了解青蛙游泳能力的进化

基本信息

批准号：
1942893
负责人：
Daniel Moen
金额：
$ 90.03万
依托单位：
Oklahoma State University
依托单位国家：
美国
项目类别：
Continuing Grant
财政年份：
2020
资助国家：
美国
起止时间：
2020-08-01 至 2025-07-31
项目状态：
未结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1942893&HistoricalAwards=false
关键词：
CAREER Macroevolutionary Biomechanics Integrating Morphology

项目摘要

Biomechanics has contributed a rich understanding of the physical principles that dictate organismal form and function, but the field has been slow to incorporate study of the evolution of mechanical diversity. In this CAREER project, the principal investigator (PI) will combine experiments on live organisms, computer modeling, and statistical analyses of the evolution of species differences to understand the evolution of diversity of body form and movement. The project will focus on (1) how different body structures scale with body size; (2) how the size of these structures and different behavioral strategies affect aquatic locomotion (i.e. swimming); (3) how sensitive swimming performance is to variation in such variables; and (4) how these relationships between form and function have affected long-term evolutionary change in swimming performance across 140 species of frogs and toads around the world. The key intellectual contribution of the project will be to develop an evolutionarily explicit approach to studies of form, function, and their diversity across species. The project will also more broadly support scientific capacity in the USA by (1) training secondary science teachers in research methods, evolutionary concepts, and integration of research into their classrooms; (2) training undergraduate students in the study of animal movement and research methods through in-class research projects; and (3) training young researchers in biomechanics to more directly incorporate evolutionary analysis methods into their projects. This project integrates biomechanical modeling, kinematics from high-speed videos, and phylogenetic comparative methods to understand the evolution of form-function relationships and their impact on macroevolution of morphology and swimming performance in anurans. The project has three key aims. In Aim 1 the PI will examine the evolution of allometry in locomotor morphology, highlighting how to leverage phylogenetic comparative methods to best estimate interspecific allometric scaling exponents. In Aim 2, he will address the mechanics and scaling of swimming in anurans. He will develop and empirically test a mathematical model of the complete swimming stroke in frogs, then use the model and phylogenetic comparative methods to explain the scaling between peak swimming velocity and body mass. In Aim 3, the PI will examine the sensitivity of swimming performance to different morphological variables through both mathematical and statistical modeling, and he will test the tempo and mode of morphological and swimming performance evolution as a function of mechanical sensitivity. The intellectual merit of the project primarily stems from integrating disparate methods (experiments, mathematical modeling, phylogenetic analyses) and providing an evolutionary comparative framework for testing general physical principles and their influence on the macroevolution of form and function. The broader impacts of the project will result from developing secondary education in scientific research and evolutionary concepts in the PI's state, integrating research training into undergraduate laboratories, and training young researchers in biomechanics in phylogenetic comparative methods workshops. This project is jointly funded by the Physiological Mechanisms and Biomechanics Program of BIO-Integrative Organismal Systems and the Established Program to Support Competitive Research (EPSCoR).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

生物力学对决定有机体形态和功能的物理原理做出了丰富的理解，但该领域对机械多样性进化的研究进展缓慢。在这个CAREER项目中，首席研究员（PI）将结合活体生物实验、计算机建模和物种差异进化的统计分析来了解身体形态和运动多样性的进化。该项目将重点关注(1)不同的身体结构如何随体型的变化而变化；(2)这些结构的大小和不同的行为策略如何影响水中运动（即游泳）；(3)游泳成绩对这些变量的变化有多敏感；(4)形式和功能之间的关系如何影响世界各地140种青蛙和蟾蜍游泳性能的长期进化变化。该项目的关键智力贡献将是发展一种明确的进化方法来研究形式、功能及其跨物种的多样性。该项目还将通过以下方式更广泛地支持美国的科学能力：(1)在研究方法、进化概念和将研究融入课堂方面培训中学科学教师；(2)通过课堂研究项目，培养本科生对动物运动和研究方法的研究；(3)培训年轻的生物力学研究人员更直接地将进化分析方法纳入他们的项目中。本项目整合了生物力学建模、高速视频运动学和系统发育比较方法，以了解形态-功能关系的演变及其对anurans形态和游泳性能的宏观进化的影响。该项目有三个主要目标。在Aim 1中，PI将研究运动形态中异速发育的演变，强调如何利用系统发育比较方法来最好地估计种间异速发育指数。在目标2，他将解决的机制和缩放游泳在anurans。他将开发并实证测试青蛙完整游泳动作的数学模型，然后使用该模型和系统发育比较方法来解释峰值游泳速度和体重之间的比例关系。在Aim 3中，PI将通过数学和统计建模来检验游泳表现对不同形态变量的敏感性，他将测试形态和游泳表现进化的速度和模式作为机械敏感性的函数。该项目的智力价值主要源于整合不同的方法（实验、数学建模、系统发育分析），并为测试一般物理原理及其对形式和功能的宏观进化的影响提供了一个进化比较框架。该项目将产生更广泛的影响，包括在PI州发展科学研究和进化概念的中等教育，将研究培训纳入本科实验室，以及在系统发育比较方法研讨会上培训生物力学方面的年轻研究人员。本项目由生物综合有机体系统生理机制和生物力学计划和支持竞争研究的既定计划（EPSCoR）共同资助。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

期刊论文数量（6）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Bridging Performance and Adaptive Landscapes to Understand Long-Term Functional Evolution

连接性能和适应性景观以了解长期功能演化

DOI：
10.1086/725416
发表时间：
2023
期刊：
Physiological and Biochemical Zoology
影响因子：
1.6
作者：
Simon, Monique Nouailhetas;Moen, Daniel S.
通讯作者：
Moen, Daniel S.

Phylogenetic analysis of adaptation in comparative physiology and biomechanics: overview and a case study of thermal physiology in treefrogs

比较生理学和生物力学适应的系统发育分析：树蛙热生理学概述和案例研究

DOI：
10.1242/jeb.243292
发表时间：
2022
期刊：
Journal of Experimental Biology
影响因子：
2.8
作者：
Moen, Daniel S.;Cabrera-Guzmán, Elisa;Caviedes-Solis, Itzue W.;González-Bernal, Edna;Hanna, Allison R.
通讯作者：
Hanna, Allison R.

Ecology, sexual dimorphism, and jumping evolution in anurans