Emerging Roles for the Nucleolus - American Society for Biochemistry and Molecular Biology Symposium

该项目的总体目标是促进下一代研究人员的出勤，教育，参与和整合到核仁生物学中。 该会议由美国生物化学和分子生物学协会（ASBMB）组织。 2017年首次举办，2019年将举办第二届。 这个会议系列填补了生物学会议的空白，因为它是过去10年来唯一一个专门讨论核仁生物学的会议。会议将向早期职业科学家介绍一系列领导者和观点，并将允许早期职业科学家分享他们的观点，帮助他们成为未来的领导者。会议的规模和设置促进了科学讨论和合议，合作成为一项成果。核仁是一种核细胞器，许多科学家通常不会聚集在一起，从研究生物物理特性的科学家到试图了解模型生物基本功能的科学家，再到那些针对癌症和罕见发育综合征的科学家。所有这些人都在这次会议上团结在一个屋檐下，以促进沟通。对于任何领域的蓬勃发展，必须支持不同的观点，并建立下一代的领导者，这是本提案的主要目标。这个跨学科的会议将集中在一系列与核仁生物学相关的主题。这些包括核糖体DNA序列的稳定性和多样性，核仁的生物物理特性，成像方法的新进展，以及核仁在健康，压力和疾病中的功能。该计划旨在促进互动和讨论，包括海报会议和共享餐，包括“会见专家”午餐，高级领导人与一群早期职业科学家就科学和职业相关主题进行非正式对话。除了10位受邀演讲者外，还选择了24篇摘要用于平台演示，其中14篇来自早期职业科学家，主要是博士后和研究生。组织者为实现包容性和多样性作出了重大努力。 会议的组织框架包括一个由资深科学家和初出茅庐的科学家组成的团队，他们担任共同组织者和会议主席。会议的男女发言者人数大致相等，所有关于平台介绍的要求都得到了满足。 促进国际讨论，该计划包括来自九个国家的发言者。 演讲者可以选择撰写一篇评论文章，发表在《生物化学学会会刊》上。为了提高公众的科学意识，2019年的会议将推出STEAM计划，将核仁的艺术图像组装成艺术页面并制作成横幅。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The overarching objective of the project is to facilitate the attendance, education, participation, and integration of the next generation of researchers into nucleolar biology. The conference is organized by the American Society of Biochemistry and Molecular Biology (ASBMB). It was held for the first time in 2017 and will be held for the second time in 2019. This conference series fills a gap in biology meetings because it is the only conference devoted to nucleolar biology in the last 10 years. The conference will introduce early career scientists to an array of leaders and perspectives and will allow early career scientists to share their perspectives, helping them to become the leaders of the future. The meeting size and setting fosters scientific discussion and collegiality, with collaborations emerging as one outcome. The nucleolus is a nuclear organelle of interest to a wide array of scientists who do not normally convene, from those studying the biophysical properties to those trying to understand basic functions in model organisms, to those targeting its activity in cancer and rare developmental syndromes. All of these individuals are united under one roof at this meeting to foster communication. For any field to flourish, it is imperative to support diverse perspectives and build the next generation of leaders, which is the main objective of this proposal.This interdisciplinary conference will focus on a range of topics related to nucleolar biology. These include the stability and diversity of ribosomal DNA sequences, the biophysical properties of the nucleolus, new advances in imaging methods, and the function of the nucleolus in health, stress and disease. The program is designed to facilitate interactions and discussions, with a poster session and shared meals, including a "meet the experts" lunch in which senior leaders are seated with a group of early career scientists for informal conversation about science and career related topics. In addition to ten invited speakers, twenty-four abstracts were chosen for platform presentations of which fourteen are from early career scientists, primarily postdocs, and graduate students. Significant efforts have been made by the organizers for inclusion and diversity. The meeting's organizational framework includes a team of both a senior and early career scientist as co-organizers and session chairs. The conference has a roughly equal split between male and female speakers, and all requests for a platform presentation were accommodated. Promoting international discussions, the program includes speakers from nine countries. Speakers will have the option to write a review article for publication in Biochemical Society Transactions. To promote scientific awareness with the public, the 2019 meeting boasts a STEAM initiative, in which artistic images of nucleoli will be assembled into an art page and made into a banner.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.