Roles of emerging pollutants in spreading antimicrobial resistance

新出现的污染物在传播抗菌素耐药性方面的作用

• 批准号: DE240100842
• 负责人: Dr Ji Lu
• 金额: $ 31.5万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE240100842
• 关键词: Roles; emerging; pollutants; spreading; antimicrobial

Antimicrobial resistance is a growing global challenge, yet the impact of environmental agents on the spread of antimicrobial resistance is poorly understood. Drawing on my recent findings and a tight integration of a model microbial ecology system, this project aims to investigate the impact of environmental pollutants on the colonisation and spread of antimicrobial resistance in situ ecological communities. This project expects to generate new knowledge at the forefront of research into antimicrobial resistance in a complex ecosystem. The outcomes should provide a deep mechanistic understanding of environmental factors associated with antimicrobial resistance, with applications to antimicrobial resistance risk management for One Health.

抗菌素耐药性是日益增长的全球挑战，但环境药物对抗菌耐药性传播的影响很少。借鉴了我最近的发现以及模型微生物生态系统的紧密整合，该项目旨在研究环境污染物对抗菌耐药性在原位生态社区的定殖和传播的影响。该项目预计将在复杂的生态系统中产生对抗菌抗性研究的最前沿。结果应提供对与抗菌耐药性相关的环境因素的深刻理解，并适用于一种健康的抗菌耐药风险管理。