Development of an immunology toolbox to combat emerging marsupial diseases

疾病越来越成为澳大利亚野生动物数量下降的一个驱动因素。然而，99%以上的脊椎动物物种的基本免疫学工具是稀缺的，限制了我们预防和应对新兴和地方性疾病的能力，如魔鬼面部肿瘤病和摇摆负鼠病。该项目的总体目标是通过开发一个早该开发的多物种有袋动物免疫学工具箱来改善野生动物健康并填补有袋动物免疫学的空白。加快颌面部肿瘤病疫苗进展和保护性免疫学研究需要工具箱。它将扩大我们对塔斯马尼亚越来越多报道的不稳定负鼠病病毒以及该病毒对其他负鼠物种构成的风险的了解。

Disease is increasingly a driver of wildlife population declines in Australia. However, basic immunology tools for >99% of vertebrate species are scarce, limiting our ability to prevent and respond to emerging and endemic diseases, such as devil facial tumour disease and wobbly possum disease. The overarching goal of this project is to improve wildlife health and fill the marsupial immunology gap by developing a long-overdue multispecies marsupial immunology toolbox. The toolbox is needed to accelerate devil facial tumour disease vaccine progress and conservation immunology research. It will expand our knowledge of wobbly possum disease virus that is increasingly reported in Tasmania and the risk posed by the virus to other possum species.