Selective secretion: a novel mechanism of protein trafficking and its role in Phytophthora pathogenicity

重要的农业作物和3000多种澳大利亚本土植物容易受到疫霉引起的疾病的影响，疫霉是一种生活在土壤中的类似真菌的病原体。经济损失超过2亿美元/年，自然生态系统遭到大规模破坏。疫霉的防治依赖于已经出现抗药性的有限数量的化学抑制剂。迫切需要新的控制策略。这项研究将探索最近在疫霉细胞中发现的一种新的感染物质释放机制，并将增加我们对疫霉如何感染寄主植物的理解，为开发新的、环境安全的抑制剂提供重要信息。

Agriculturally important crops and over 3,000 Australian native plants are susceptible to diseases caused by Phytophthora, fungus-like pathogens that live in the soil. Economic losses exceed $200m pa and natural ecosystems are being destroyed on a vast scale. Phytophthora control depends upon a limited number of chemical inhibitors to which resistance has already emerged. New control strategies are urgently needed. This research will investigate a novel mechanism for release of infection material recently discovered in Phytophthora cells, and will increase our understanding of how Phytophthora infects host plants, providing vital information required for the development of new, environmentally-safe inhibitors.