6th International Conference of Quantitative Genetics (ICQG6)

第六届国际数量遗传学会议（ICQG6）

• 批准号: 2010561
• 负责人: Bruce Weir
• 金额: $ 4.73万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-15 至 2021-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2010561&HistoricalAwards=false
• 关键词: 6th; International; Conference; Quantitative; Genetics

The Sixth International Conference of Quantitative Genetics (ICQG6) will be held in Brisbane, Australia, June 2021. Quantitative genetics is concerned with traits for which variation between individuals is controlled in part by DNA differences between individuals. These traits include those that are affected by environmental factors and change during evolution and that affect human health or economic traits in domesticated plants and animals. The hereditary component for these traits is often complex and requires sophisticated mathematical and statistical analyses to relate observed trait values to genetic profiles. Quantitative geneticists are now addressing very large genetic datasets made possible by advances in molecular biology, with human genetic studies now capable of revealing information for a billion separate genetic elements, and the scale of data is also large for plants and animals. The ICQG6 will bring over 500 scientists and students together to survey the current state of the field and to consider future activities.The Sixth International Conference of Quantitative Genetics (ICQG6) to be held in Brisbane, Australia, June 2021. Important health problems will are addressed in this application by an emphasis on the genetic determinants of human disease. Studies of disease rest heavily on sound statistical methodology. Many new statistical techniques that address complex traits and the integration of genotype, gene expression and clinical trait data will be covered in the Conference. Advances in human health often follow the studies made on model organisms to be described at the ICQG6. Use of model organisms requires an understanding of the shared evolutionary history of man and other organisms, and some speakers will address the evolution of quantitative traits. Quantitative genetic methodology, especially techniques for mapping quantitative trait loci (QTL), is often developed for plant and animal populations where controlled crosses can be made. Advances in plant and animal breeding also lead to improved human health by increasing the quality and quantity of food. The technological advances of the last decade have meant that quantitative genetic studies are being conducted at an unprecedented scale. Moreover, there are also studies on the quantitative genetics of omics traits, including at the single-cell level. Many conference attendees develop new methods that are applicable across a range of species and traits. In particular, progress in human genetics has been made with methodology developed in livestock genetics. Dialog between methodologists across species has been found to provide new ideas, new directions and new ways of thinking.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

第六次国际定量遗传学会议（ICQG6）将于2021年6月在澳大利亚布里斯班举行。定量遗传学与个体之间的DNA差异部分控制的个体之间的差异有关。这些特征包括那些受环境因素影响和进化期间变化的特征，以及影响驯养动植物中人类健康或经济特征的特征。这些特征的遗传成分通常很复杂，需要复杂的数学和统计分析才能将观察到的性状值与遗传特征相关联。现在，定量遗传学家正在解决通过分子生物学的进步使得非常大的遗传数据集，现在人类遗传学研究能够揭示数十亿个单独的遗传元素的信息，并且数据的规模对于植物和动物来说也很大。 ICQG6将将500多名科学家和学生聚集在一起，调查该领域的现状并考虑未来的活动。第六次国际定量遗传学会议（ICQG6）将于2021年6月在澳大利亚布里斯班举行。在此应用中，将通过对人类疾病的遗传确定性的重点来解决重要的健康问题。疾病的研究严重取决于合理的统计方法。会议将涵盖许多针对复杂性状以及基因型，基因表达和临床性状数据的整合的新统计技术。人类健康的进步经常遵循对ICQG6上描述的模型生物的研究。使用模型生物需要了解人类和其他生物的共同进化史，一些说话者将解决定量特征的演变。定量遗传学方法，尤其是用于绘制定量性状基因座（QTL）的技术，通常是针对可以进行控制十字的动植物种群开发的。动植物育种的进步还通过提高食物的质量和数量来改善人类健康。过去十年的技术进步意味着定量遗传研究正在以前所未有的规模进行。此外，还研究了OMICS性状的定量遗传学，包括在单细胞水平上。许多会议参与者开发了适用于各种物种和特征的新方法。特别是，人类遗传学的进展是通过牲畜遗传学中发展的方法来取得的。已经发现，跨物种的方法学家之间的对话提供了新的想法，新的方向和新的思维方式。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子优点和更广泛的影响评估标准通过评估来支持的。