6th International Conference of Quantitative Genetics (ICQG6)

第六届国际数量遗传学会议（ICQG6）将于2021年6月在澳大利亚布里斯班举行。数量遗传学关注的是个体之间的变异部分由个体之间的DNA差异控制的性状。这些性状包括在进化过程中受环境因素和变化影响的性状，以及影响人类健康或驯化动植物的经济性状的性状。这些性状的遗传成分通常是复杂的，需要复杂的数学和统计分析来将观察到的性状值与遗传谱联系起来。由于分子生物学的进步，定量遗传学家现在正在处理非常大的遗传数据集，人类遗传研究现在能够揭示10亿个独立遗传元素的信息，植物和动物的数据规模也很大。ICQG6将汇集500多名科学家和学生，调查该领域的现状并考虑未来的活动。第六届国际数量遗传学会议（ICQG6）将于2021年6月在澳大利亚布里斯班举行。重要的健康问题将通过强调人类疾病的遗传决定因素来解决。疾病研究在很大程度上依赖于可靠的统计方法。会议将讨论许多处理复杂性状和整合基因型、基因表达和临床性状数据的新统计技术。人类健康方面的进展往往伴随着将在ICQG6上描述的模式生物的研究。使用模式生物需要了解人类和其他生物共同的进化史，一些演讲者将讨论数量性状的进化。定量遗传方法，特别是定量性状位点（QTL）定位技术，通常是为植物和动物群体开发的，在那里可以进行控制杂交。植物和动物育种的进步也通过提高食物的质量和数量来改善人类健康。过去十年的技术进步意味着定量基因研究正在以前所未有的规模进行。此外，也有组学性状的数量遗传学研究，包括在单细胞水平。许多与会者开发了适用于各种物种和性状的新方法。特别是，人类遗传学已取得进展的方法开发的牲畜遗传学。人们发现，跨物种的方法论家之间的对话可以提供新的想法、新的方向和新的思维方式。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The Sixth International Conference of Quantitative Genetics (ICQG6) will be held in Brisbane, Australia, June 2021. Quantitative genetics is concerned with traits for which variation between individuals is controlled in part by DNA differences between individuals. These traits include those that are affected by environmental factors and change during evolution and that affect human health or economic traits in domesticated plants and animals. The hereditary component for these traits is often complex and requires sophisticated mathematical and statistical analyses to relate observed trait values to genetic profiles. Quantitative geneticists are now addressing very large genetic datasets made possible by advances in molecular biology, with human genetic studies now capable of revealing information for a billion separate genetic elements, and the scale of data is also large for plants and animals. The ICQG6 will bring over 500 scientists and students together to survey the current state of the field and to consider future activities.The Sixth International Conference of Quantitative Genetics (ICQG6) to be held in Brisbane, Australia, June 2021. Important health problems will are addressed in this application by an emphasis on the genetic determinants of human disease. Studies of disease rest heavily on sound statistical methodology. Many new statistical techniques that address complex traits and the integration of genotype, gene expression and clinical trait data will be covered in the Conference. Advances in human health often follow the studies made on model organisms to be described at the ICQG6. Use of model organisms requires an understanding of the shared evolutionary history of man and other organisms, and some speakers will address the evolution of quantitative traits. Quantitative genetic methodology, especially techniques for mapping quantitative trait loci (QTL), is often developed for plant and animal populations where controlled crosses can be made. Advances in plant and animal breeding also lead to improved human health by increasing the quality and quantity of food. The technological advances of the last decade have meant that quantitative genetic studies are being conducted at an unprecedented scale. Moreover, there are also studies on the quantitative genetics of omics traits, including at the single-cell level. Many conference attendees develop new methods that are applicable across a range of species and traits. In particular, progress in human genetics has been made with methodology developed in livestock genetics. Dialog between methodologists across species has been found to provide new ideas, new directions and new ways of thinking.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.