6th International Conference of Quantitative Genetics (ICQG6)

第六届国际数量遗传学会议（ICQG6）

• 批准号: 2010561
• 负责人: Bruce Weir
• 金额: $ 4.73万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-15 至 2021-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2010561&HistoricalAwards=false
• 关键词: 6th; International; Conference; Quantitative; Genetics

The Sixth International Conference of Quantitative Genetics (ICQG6) will be held in Brisbane, Australia, June 2021. Quantitative genetics is concerned with traits for which variation between individuals is controlled in part by DNA differences between individuals. These traits include those that are affected by environmental factors and change during evolution and that affect human health or economic traits in domesticated plants and animals. The hereditary component for these traits is often complex and requires sophisticated mathematical and statistical analyses to relate observed trait values to genetic profiles. Quantitative geneticists are now addressing very large genetic datasets made possible by advances in molecular biology, with human genetic studies now capable of revealing information for a billion separate genetic elements, and the scale of data is also large for plants and animals. The ICQG6 will bring over 500 scientists and students together to survey the current state of the field and to consider future activities.The Sixth International Conference of Quantitative Genetics (ICQG6) to be held in Brisbane, Australia, June 2021. Important health problems will are addressed in this application by an emphasis on the genetic determinants of human disease. Studies of disease rest heavily on sound statistical methodology. Many new statistical techniques that address complex traits and the integration of genotype, gene expression and clinical trait data will be covered in the Conference. Advances in human health often follow the studies made on model organisms to be described at the ICQG6. Use of model organisms requires an understanding of the shared evolutionary history of man and other organisms, and some speakers will address the evolution of quantitative traits. Quantitative genetic methodology, especially techniques for mapping quantitative trait loci (QTL), is often developed for plant and animal populations where controlled crosses can be made. Advances in plant and animal breeding also lead to improved human health by increasing the quality and quantity of food. The technological advances of the last decade have meant that quantitative genetic studies are being conducted at an unprecedented scale. Moreover, there are also studies on the quantitative genetics of omics traits, including at the single-cell level. Many conference attendees develop new methods that are applicable across a range of species and traits. In particular, progress in human genetics has been made with methodology developed in livestock genetics. Dialog between methodologists across species has been found to provide new ideas, new directions and new ways of thinking.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

第六届国际数量遗传学会议（ICQG 6）将于2021年6月在澳大利亚布里斯班举行。数量遗传学关注的是个体之间的变异部分由个体之间的DNA差异控制的性状。这些性状包括那些受环境因素影响并在进化过程中发生变化的性状，以及那些影响人类健康或驯化动植物经济性状的性状。这些性状的遗传成分往往很复杂，需要复杂的数学和统计分析，将观察到的性状值与遗传图谱联系起来。定量遗传学家现在正在处理分子生物学进步所带来的非常大的遗传数据集，人类遗传研究现在能够揭示十亿个独立遗传元素的信息，植物和动物的数据规模也很大。ICQG 6将汇集500多名科学家和学生，调查该领域的现状，并考虑未来的活动。第六届国际数量遗传学会议（ICQG 6）将于2021年6月在澳大利亚布里斯班举行。本申请将通过强调人类疾病的遗传决定因素来解决重要的健康问题。疾病研究在很大程度上依赖于可靠的统计方法。许多新的统计技术，解决复杂的性状和整合的基因型，基因表达和临床性状数据将在会议上讨论。人类健康方面的进展往往是在ICQG第六届会议上对模式生物进行研究之后取得的。使用模式生物需要了解人类和其他生物的共同进化历史，一些演讲者将讨论数量性状的进化。数量遗传学方法，特别是数量性状基因座（QTL）定位技术，经常被开发用于植物和动物群体，其中可以进行控制杂交。植物和动物育种的进步也通过提高食物的质量和数量来改善人类健康。过去十年的技术进步意味着定量遗传学研究正在以前所未有的规模进行。此外，还有关于组学特征的数量遗传学研究，包括在单细胞水平上的研究。许多与会者开发了适用于一系列物种和性状的新方法。特别是，人类遗传学方面的进展与牲畜遗传学方面的方法有关。跨物种的方法学家之间的对话被发现提供了新的想法，新的方向和新的思维方式。该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估来支持。