6th International Conference of Quantitative Genetics (ICQG6)

第六届国际数量遗传学大会(ICQG6)将于2021年6月在澳大利亚布里斯班举行。数量遗传学研究的是个体间的变异部分受个体间DNA差异控制的特征。这些特征包括那些受环境因素影响和在进化过程中发生变化，并影响人类健康或驯养动植物的经济特征的特征。这些性状的遗传成分通常是复杂的，需要复杂的数学和统计分析来将观察到的性状值与基因图谱联系起来。定量遗传学家现在正在研究分子生物学的进步使之成为可能的非常大的遗传数据集，人类基因研究现在能够揭示10亿个不同的遗传元素的信息，植物和动物的数据规模也很大。第六届国际数量遗传学会议(ICQG6)将召集500多名科学家和学生一起考察该领域的现状并考虑未来的活动。第六届国际数量遗传学会议(ICQG6)将于2021年6月在澳大利亚布里斯班举行。在这一应用中，将通过强调人类疾病的遗传决定因素来解决重要的健康问题。对疾病的研究在很大程度上依赖于健全的统计方法。会议将讨论许多新的统计技术，这些技术涉及复杂的特征以及基因、基因表达和临床特征数据的整合。人类健康方面的进展往往是在第六次国际质量保证会议上描述的对模式生物的研究之后取得的。使用模式生物需要了解人类和其他生物共同的进化史，一些演讲者将讨论数量性状的进化。数量遗传方法，特别是数量性状基因座(QTL)定位技术，通常是针对可以进行控制杂交的动植物种群而发展起来的。动植物育种的进步也通过提高食物的质量和数量来改善人类健康。过去十年的技术进步意味着，定量基因研究正在以前所未有的规模进行。此外，还有关于组学性状的数量遗传学的研究，包括在单细胞水平上的研究。许多与会者开发了适用于一系列物种和特征的新方法。特别是，随着家畜遗传学方法学的发展，人类遗传学取得了进展。不同物种的方法学家之间的对话被发现提供了新的想法、新的方向和新的思维方式。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

The Sixth International Conference of Quantitative Genetics (ICQG6) will be held in Brisbane, Australia, June 2021. Quantitative genetics is concerned with traits for which variation between individuals is controlled in part by DNA differences between individuals. These traits include those that are affected by environmental factors and change during evolution and that affect human health or economic traits in domesticated plants and animals. The hereditary component for these traits is often complex and requires sophisticated mathematical and statistical analyses to relate observed trait values to genetic profiles. Quantitative geneticists are now addressing very large genetic datasets made possible by advances in molecular biology, with human genetic studies now capable of revealing information for a billion separate genetic elements, and the scale of data is also large for plants and animals. The ICQG6 will bring over 500 scientists and students together to survey the current state of the field and to consider future activities.The Sixth International Conference of Quantitative Genetics (ICQG6) to be held in Brisbane, Australia, June 2021. Important health problems will are addressed in this application by an emphasis on the genetic determinants of human disease. Studies of disease rest heavily on sound statistical methodology. Many new statistical techniques that address complex traits and the integration of genotype, gene expression and clinical trait data will be covered in the Conference. Advances in human health often follow the studies made on model organisms to be described at the ICQG6. Use of model organisms requires an understanding of the shared evolutionary history of man and other organisms, and some speakers will address the evolution of quantitative traits. Quantitative genetic methodology, especially techniques for mapping quantitative trait loci (QTL), is often developed for plant and animal populations where controlled crosses can be made. Advances in plant and animal breeding also lead to improved human health by increasing the quality and quantity of food. The technological advances of the last decade have meant that quantitative genetic studies are being conducted at an unprecedented scale. Moreover, there are also studies on the quantitative genetics of omics traits, including at the single-cell level. Many conference attendees develop new methods that are applicable across a range of species and traits. In particular, progress in human genetics has been made with methodology developed in livestock genetics. Dialog between methodologists across species has been found to provide new ideas, new directions and new ways of thinking.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.