FASEB SRC: The 6th International Conference on Retinoids

FASEB SRC：第六届类维生素A国际会议

• 批准号: 10468377
• 负责人: MAUREEN A KANE
• 金额: $ 2万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10468377
• 关键词: Address; Alzheimer' s Disease; American; Area; Award; Biochemical; Biological Process; Biology; Clinical; Collaborations; Databases; Development; Diabetes Mellitus; Discipline; Disease; Embryonic Development; Ensure; Enzymatic Biochemistry; Event; Funding; Goals; Health; Homeostasis; Human; Immune System Diseases; Immunity; Immunologist; Immunology; Individual; International; Malignant Neoplasms; Mediating; Metabolic Diseases; Metabolic dysfunction; Metabolism; Molecular; Molecular Immunology; Nutritional; Ohio; Oral; Participant; Pathology; Pharmacology; Physiological; Postdoctoral Fellow; Process; Reporter; Reporting; Reproduction; Request for Applications; Research; Research Activity; Research Personnel; Research Project Grants; Retinoid Receptor; Retinoids; Science; Scientist; Senior Scientist; Signal Transduction; Societies; Structural Biologist; Therapeutic; Time; Training; Translational Research; Travel; Underrepresented Populations; United States National Institutes of Health; Universities; Vision; Visual; Vitamin A; Woman; Work; base; bench to bedside; capsule; career; cell type; disorder prevention; equity diversity and inclusion; fundamental research; graduate student; meetings; nervous system disorder; novel; nutrition; posters; regenerative biology; skin disorder; stem cell biology; stem cells; symposium; training opportunity

PROJECT SUMMARY / ABSTRACT This NIH R13 application requests requesting partial funding for the 2022 Federation of American Societies for Experimental Biology (FASEB) “6th International Conference on Retinoids” that will be held at Ohio University, Athens, OH from June 5, 2022 to June 10, 2022. The FASEB Science Research Conference on Retinoids has been held every other year since 1982 where the meeting planned for 2022 will be the 21st FASEB Science Research Conference on Retinoids. This biennial research conference has been very well attended (ranging from 100 to 200 attendees over the past 40 years) and remains the only major national and international conference committed to focus on the studies of retinoids, and to comprehensively address the broad spectrum of retinoid actions and application in an integrative manner. While the mechanisms of action and the biological functions of retinoids have been intensively studied, there is an increasing need for understanding and applying retinoids in human nutrition and diseases. Currently, a great deal of research activity is supported by the NIH (the NIH RePORTER database indicates 2190 NIH funded individual research grants involving aspects of retinoid/vitamin A biology). The main topics to be addressed include both basic and translational fronts of retinoid biology: 3 sessions on retinoid mechanisms (I, Retinoid receptors, retinoid receptor-mediated biology; II, Retinoid metabolism, homeostasis, and enzymology; III, Development, stem cell and regenerative biology); 3 sessions on retinoids and disease (I, Immune disorders and immunology; II, Signaling and metabolic dysfunction; III, Cancer and related pathologies), and 2 sessions on molecular therapeutics (I, Retinoid mechanisms and novel targets; II, Rexinoids and novel pharmacological applications). The overall goal is to bring together a group of committed investigators (senior scientists, mid-career scientists, junior scientists, postdoctoral fellows, and graduate students), who work in diverse disciplines (as biochemists, molecular biologists, nutritional scientists, cancer researchers, vision researchers, stem cell biologists, biophysicists, structural biologists, immunologists, chemists, and clinicians) to present and discuss their latest research findings that share a common focus on the retinoids. To encourage new/young investigators and trainees to attend this meeting, we plan to offer six career- oriented training sessions and six meet-the-expert sessions. To increase visibility of early-stage investigators and trainees through oral presentations, we plan eight speaking opportunities and twenty-nine short talk and capsule reports presentations to be chosen from the submitted abstracts. This meeting has been strongly supported by NIH in the past. We respectfully request partial support for the 2022 FASEB Retinoid Conference to increase the attendance by under-represented and women scientists, trainees, postdoctoral fellows, and early- stage investigators to facilitate entry into this research area in order to spur interdisciplinary and translational science as well as collaborations between basic scientists and clinicians.

项目概要/摘要 此 NIH R13 申请要求为 2022 年美国社团联合会申请部分资金 实验生物学（FASEB）“第六届类维生素A国际会议”将在俄亥俄大学举行， 俄亥俄州雅典，2022 年 6 月 5 日至 2022 年 6 月 10 日。FASEB 类维生素A 科学研究会议 自 1982 年以来每隔一年举行一次，计划于 2022 年举行的第 21 届 FASEB Science 会议 类维生素A研究会议。这次两年一度的研究会议出席人数非常多（范围广泛） 过去 40 年来，与会者人数从 100 人增加到 200 人），并且仍然是唯一的主要国内和国际 会议致力于重点关注类维生素A的研究，并全面解决广谱问题 类视黄醇的作用和以综合方式应用。虽然作用机制和生物学 类维生素A的功能已被深入研究，对理解和应用的需求越来越大 类维生素A在人类营养和疾病中的作用。目前，大量的研究活动得到了 NIH 的支持 （NIH RePORTER 数据库显示 2190 项 NIH 资助的个人研究经费涉及以下方面： 类视黄醇/维生素 A 生物学）。讨论的主要主题包括类维生素A的基础和转化前沿 生物学：关于类维生素A机制的3个课程（I，类维生素A受体，类维生素A受体介导的生物学；II，类维生素A 新陈代谢、体内平衡和酶学； III、发育、干细胞和再生生物学）； 3 节课 类维生素A与疾病（I，免疫性疾病和免疫学；II，信号传导和代谢功能障碍；III， 癌症和相关病理学），以及 2 场分子疗法课程（I，类视黄醇机制和新型 目标； II，Rexinoids 和新的药理学应用）。总体目标是聚集一群 忠诚的研究人员（高级科学家、职业中期科学家、初级科学家、博士后研究员和 研究生），在不同学科工作（如生物化学家、分子生物学家、营养科学家、 癌症研究人员、视觉研究人员、干细胞生物学家、生物物理学家、结构生物学家、免疫学家、 化学家和临床医生）展示并讨论他们共同关注的最新研究成果 类维生素A。为了鼓励新的/年轻的研究者和实习生参加这次会议，我们计划提供六种职业- 定向培训课程和六次专家见面会。提高早期研究人员的知名度 通过口头演讲和学员的交流，我们计划了八次演讲机会和二十九次简短演讲， 胶囊报告从提交的摘要中选择演示文稿。这次会议得到了强烈 过去曾得到 NIH 的支持。我们诚挚地请求对 2022 年 FASEB Retinoid 会议提供部分支持 增加代表性不足的女性科学家、实习生、博士后研究员和早期研究人员的出席率 阶段研究人员促进进入该研究领域，以促进跨学科和转化 科学以及基础科学家和临床医生之间的合作。