FASEB SRC: The 6th International Conference on Retinoids

项目摘要/摘要

PROJECT SUMMARY / ABSTRACT This NIH R13 application requests requesting partial funding for the 2022 Federation of American Societies for Experimental Biology (FASEB) “6th International Conference on Retinoids” that will be held at Ohio University, Athens, OH from June 5, 2022 to June 10, 2022. The FASEB Science Research Conference on Retinoids has been held every other year since 1982 where the meeting planned for 2022 will be the 21st FASEB Science Research Conference on Retinoids. This biennial research conference has been very well attended (ranging from 100 to 200 attendees over the past 40 years) and remains the only major national and international conference committed to focus on the studies of retinoids, and to comprehensively address the broad spectrum of retinoid actions and application in an integrative manner. While the mechanisms of action and the biological functions of retinoids have been intensively studied, there is an increasing need for understanding and applying retinoids in human nutrition and diseases. Currently, a great deal of research activity is supported by the NIH (the NIH RePORTER database indicates 2190 NIH funded individual research grants involving aspects of retinoid/vitamin A biology). The main topics to be addressed include both basic and translational fronts of retinoid biology: 3 sessions on retinoid mechanisms (I, Retinoid receptors, retinoid receptor-mediated biology; II, Retinoid metabolism, homeostasis, and enzymology; III, Development, stem cell and regenerative biology); 3 sessions on retinoids and disease (I, Immune disorders and immunology; II, Signaling and metabolic dysfunction; III, Cancer and related pathologies), and 2 sessions on molecular therapeutics (I, Retinoid mechanisms and novel targets; II, Rexinoids and novel pharmacological applications). The overall goal is to bring together a group of committed investigators (senior scientists, mid-career scientists, junior scientists, postdoctoral fellows, and graduate students), who work in diverse disciplines (as biochemists, molecular biologists, nutritional scientists, cancer researchers, vision researchers, stem cell biologists, biophysicists, structural biologists, immunologists, chemists, and clinicians) to present and discuss their latest research findings that share a common focus on the retinoids. To encourage new/young investigators and trainees to attend this meeting, we plan to offer six career- oriented training sessions and six meet-the-expert sessions. To increase visibility of early-stage investigators and trainees through oral presentations, we plan eight speaking opportunities and twenty-nine short talk and capsule reports presentations to be chosen from the submitted abstracts. This meeting has been strongly supported by NIH in the past. We respectfully request partial support for the 2022 FASEB Retinoid Conference to increase the attendance by under-represented and women scientists, trainees, postdoctoral fellows, and early- stage investigators to facilitate entry into this research area in order to spur interdisciplinary and translational science as well as collaborations between basic scientists and clinicians.