Belmont Forum Collaborative Research: PolyCone Project - An Integrated Approach for Sustainable Pathways of Marine Resources: Cone Snails in French Polynesia

该奖项为参与一个由55个国家发起的全球变化研究计划通过贝尔蒙特论坛竞争性选定的项目的美国研究人员提供支持。贝尔蒙特论坛是一个研究资助组织联盟，专注于支持以跨学科方法应对全球环境变化的挑战和机遇。它的目的是通过协调和调动国际资源，加速开展最迫切需要的国际研究，以消除对可持续性的关键障碍。每个伙伴国都在一个联合体内为其研究人员提供资金，以减轻跨越国际边界的资金需求。这一办法有助于有效利用国家资源，支持对具有全球相关性的专题进行出色的研究，最好是通过多国办法加以解决，同时认识到全球挑战需要全球解决办法。在这项合作研究行动中，伙伴机构提供了支持，以培养全球跨学科研究团队，以解决海洋可持续性方面的关键问题，包括海洋和海洋资源的养护和可持续利用，以促进可持续发展。这一复杂的挑战要求这些项目采用综合、跨学科和跨部门的方法，并将自然科学和社会科学以及政策制定者、资源管理者、行业、公民和其他社会合作伙伴聚集在一起。该奖项支持美国研究人员在由至少三个参与国的合作伙伴组成的财团中开展合作，以增加我们对加快海洋可持续利用和将全球变化的影响降至最低所需的复杂联系和途径的了解。该项目的重点是开发一种可持续养殖和收获锥形蜗牛的模式。锥螺毒素是治疗人类健康药物的重要来源，还可能具有其他重要的分子特性，具有不同的应用。锥体衍生药物的潜在益处和用途在目前的临床试验和一种锥体衍生止痛药的批准中是显而易见的。该项目将以法属波利尼西亚为重点，寻求提供关键信息，以帮助社区发展综合、道德和可持续的收获和水产养殖实践。该项目将通过一种综合的方法发展新的蓝色经济，包括在其水产养殖和毒液开采过程中的重大进展，开发一个维持和提高这些社区及其相关海洋环境和生态的可持续福祉的模式。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award provides support to U.S. researchers participating in a project competitively selected by a 55-country initiative on global change research through the Belmont Forum. The Belmont Forum is a consortium of research funding organizations focused on support for transdisciplinary approaches to global environmental change challenges and opportunities. It aims to accelerate delivery of the international research most urgently needed to remove critical barriers to sustainability by aligning and mobilizing international resources. Each partner country provides funding for their researchers within a consortium to alleviate the need for funds to cross international borders. This approach facilitates effective leveraging of national resources to support excellent research on topics of global relevance best tackled through a multinational approach, recognizing that global challenges need global solutions.Working together in this Collaborative Research Action, the partner agencies have provided support to foster global transdisciplinary research teams to address critical issues in ocean sustainability including, conservation and sustainable use of the oceans, seas and marine resources for sustainable development. This complex challenge required that the projects utilized integrated, transdisciplinary and cross-sectoral approaches and bring together natural and social sciences as well as policymakers, resource managers, industries, citizens and other societal partners. This award provides support for the U.S. researchers to cooperate in consortia that consist of partners from at least three of the participating countries to increase our knowledge of the complex linkages and pathways needed to accelerate sustainable use of oceans and minimize the effects from global change. The project focuses on developing a model to sustainably culture and harvest cone snails. Toxins of cone snails are an important source of pharmaceuticals for treating human health and may have other significant molecular properties with diverse applications. The potential benefits and uses of cone derived pharmaceuticals are evident in current clinical trials and the approval of one cone derived pain medication. This project will focus on French Polynesia and seeks to provide critical information to help communities develop integrated, ethical, and sustainable harvesting and aquaculture practices. The project will develop a model for the maintenance and enhancement of the sustainable wellbeing of these communities and their linked marine environments and ecologies through an integrated approach to developing new blue economics including significant advances in its aquaculture and venom exploitation processes.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.