SBIR Phase I: Development of Safety Accessory for Improving Performance and Minimizing Complications of Manual Ventilation (COVID-19)

这项小企业创新研究（SBIR）第一阶段项目的更广泛影响/商业潜力包括通过开发具有成本效益和用户友好的医疗设备来提高性能并最大限度地减少人工通气的并发症。气囊阀面罩（BVM）在第一反应和紧急情况下使用，以手动向无法自主呼吸的患者输送空气。在美国，每年大约使用1310万台bvm。由于缺乏反馈机制，提供者无法判断他们是否遵守通气建议，导致危及生命的并发症的高发。在重症监护室，机械呼吸机用于安全精确的空气输送，但质量不同。该项目防止了不安全人工通气的并发症，从而提高了护理质量，并为卫生系统节省了成本。该项目将有助于弥合人工和机械通气之间的差距，为COVID-19大流行期间的急救人员提供帮助。这个小企业创新研究（SBIR）第一阶段项目将推进应急气道管理科学。该技术将适应现有的治疗工作流程和供应链，同时满足COVID-19期间对更安全通风的需求。由于输送不安全的压力、容量或频率而导致的不适当的手动通气是常见的，并且无论提供者的培训或经验如何都会发生。对该问题的普遍性和严重性进行了广泛的研究，确定了对该设备的需求。研发目标是开发一种性能和安全性更接近呼吸机的设备。研究包括表征可用性、性能、功效和生物相容性。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project includes improved performance and minimized complications of manual ventilation through the development of a cost-efficient and user-friendly medical device. The bag valve mask (BVM) is used during first-response and emergencies to manually deliver air to patients unable to breathe on their own. Approximately 13.1 million BVMs are used annually in the United States. Due to a lack of feedback mechanisms, providers are unable to judge their compliance with ventilation recommendations, resulting in a high incidence of life-threatening complications. In the intensive care unit, mechanical ventilators are used for safe and precise air delivery, but the quality is different. This project prevents complications of unsafe manual ventilation, thereby improving the quality of care and providing cost savings for the health system. The project will help bridge the gap between manual and mechanical ventilation, aiding first responders in the COVID-19 pandemic. This Small Business Innovation Research (SBIR) Phase I project will advance the science of emergency airway management. This technology will fit into the existing treatment workflow and supply-chain while addressing the need for safer ventilation during COVID-19. Improper manual ventilation due to delivery of unsafe pressures, volume, or frequency is common and occurs regardless of a provider's training or experience. The prevalence and severity of the problem have been studied extensively, establishing the need for the device. The research and development goal is to develop a device that can achieve performance and safety closer to a ventilator. Studies include characterizing usability, performance, efficacy, and biocompatibility.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.