RAPID: Impact of the COVID-19 Pandemic on Child Development in the ABCD Cohort

RAPID：COVID-19 大流行对 ABCD 队列中儿童发育的影响

• 批准号: 2028680
• 负责人: Susan Tapert
• 金额: $ 20万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-01 至 2021-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2028680&HistoricalAwards=false
• 关键词: RAPID; Impact; COVID; 19; Pandemic

The coronavirus pandemic has affected children and families worldwide. In the US, schools and closed, yet there is variability across states and cities regarding pandemic recommendation on social distancing. The situation likely affects different children in different ways, due to varying levels of familial financial impact, self or family COVID-19 illness, mental health effects of social distancing and stress, online activity, scholastic activity, adult supervision, and indirect health influences of altered physical activity, sleep, and access to nutrition. The Adolescent Brain Cognitive Development project (ABCD) is a longitudinal study of 11,878 diverse youth enrolled at ages 9-10 in 2016-2018 (birth years 2006-2009) at 21 research sites around the United States. This RAPID project will design and implement a new survey, to assess personal impact of COVID-19 on ABCD participants and families. With this new information, we can leverage existing ABCD data to examine perturbations in developmental trajectories of brain functioning, neurocognition, mental health, substance use, academic achievement, and social functioning. By immediately collecting a unique set of measures that characterize the pandemic’s effects, we can make use of the existing ABCD protocol and design in this large, diverse, national sample. Results from this study will provide substantially improved guidelines for future epidemics and pandemics, and indicate potential targets for interventions when other traumas affect children.The ABCD cohort is being followed until at least age 20, with: biennial state-of-the-art neuroimaging, epigenetics/genetics, and physical activity tracking; annual cognitive testing and assessments with youth and parents on mental and physical health and development, life events and trauma exposure, culture and environment, substance use, sleep, and screen time; and biannual brief assessments of mental health and substance use. The proposed research would immediately characterize the impacts of the COVID-19 pandemic on each child via a youth and parent self-assessment that characterizes their personal level of family disruption, social distancing and its impact, attitudes, adherence to public health directives, and media exposure. This crisis provides a unique opportunity to make use of ABCD’s elaborate infrastructure and rigorous scientific processes to discern critical dimensions of behavior not previously envisioned. The impending severity of this unanticipated pandemic may result in significant influences on school-age youth for decades, and this RAPID will be critical to characterizing factors that protect and exacerbate its effects. This research will immediately examine COVID-19 related effects on youth, and how their practices around virus transmission and prevention vary as a function of family and social factors, external influences, and other characteristics.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

冠状病毒大流行影响了全世界的儿童和家庭。在美国，学校关闭，但各州和城市在大流行期间保持社交距离的建议上存在差异。 这种情况可能会以不同的方式影响不同的儿童，因为家庭经济影响、自身或家庭 COVID-19 疾病、社交距离和压力对心理健康的影响、在线活动、学业活动、成人监督以及体力活动、睡眠和营养获取改变对健康的间接影响都有不同程度的影响。 青少年大脑认知发展项目 (ABCD) 是一项对 2016 年至 2018 年（出生年份 2006-2009）在美国 21 个研究中心注册的 11,878 名 9-10 岁不同青少年的纵向研究。 该 RAPID 项目将设计并实施一项新的调查，以评估 COVID-19 对 ABCD 参与者和家庭的个人影响。有了这些新信息，我们就可以利用现有的 ABCD 数据来检查大脑功能、神经认知、心理健康、物质使用、学业成就和社会功能的发展轨迹的扰动。通过立即收集一套表征大流行影响的独特措施，我们可以在这个庞大、多样化的全国样本中利用现有的 ABCD 协议和设计。 这项研究的结果将为未来的流行病和大流行提供实质性改进的指导方针，并指出当其他创伤影响儿童时干预的潜在目标。ABCD 队列的跟踪至少到 20 岁，其中：每两年进行一次最先进的神经影像学、表观遗传学/遗传学和体力活动跟踪；与青少年和家长进行年度认知测试和评估，内容涉及身心健康和发展、生活事件和创伤暴露、文化和环境、物质使用、睡眠和屏幕时间；每年两次对心理健康和药物使用进行简短评估。 拟议的研究将通过青少年和家长的自我评估，立即描述 COVID-19 大流行对每个儿童的影响，该评估描述了他们个人的家庭破坏程度、社交距离及其影响、态度、对公共卫生指令的遵守情况和媒体曝光度。这场危机提供了一个独特的机会，可以利用 ABCD 复杂的基础设施和严格的科学流程来辨别以前未曾预见到的行为的关键维度。这种意想不到的流行病即将到来的严重性可能会对学龄青年造成数十年的重大影响，而这种快速反应对于描述保护和加剧其影响的因素至关重要。这项研究将立即研究 COVID-19 对青少年的相关影响，以及他们在病毒传播和预防方面的做法如何随着家庭和社会因素、外部影响和其他特征的变化而变化。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。