SBIR Phase I: Photoactivated coatings & cleaners to disable COVID-19 on hospital high touch surfaces

SBIR 第一阶段：光敏涂层

• 批准号: 2030025
• 负责人: Jeffrey Roeder
• 金额: $ 25.6万
• 依托单位: SONATA SCIENTIFIC LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2021-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2030025&HistoricalAwards=false
• 关键词: SBIR; Phase; Photoactivated; coatings; &amp

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is the development of new tools to reduce transmission of SARS-CoV-2 virus and the associated COVID-19 pandemic. The materials platform developed in this project will help control and prevent surface-borne transmission of viruses, bacteria, and other pathogens with the potential to cause pandemics. The project will advance a robust coating that can be applied at point-of-use to reduce the hand-to-face spread of COVID-19. This technology may help reduce infection transmission among patients and care providers. This SBIR Phase I project proposes to develop durable and non-toxic virucidal coatings containing visible-light-stimulated photocatalytic materials and a dark active material in a robust polymer matrix. The continuous antipathogenic action is activated with room light; the dark active material provides disinfecting species between daily cleanings. The coating will disable viruses, such as SARS-CoV-2, as well as other bacteria and bacterial spores. These objectives overcome key drawbacks of current antimicrobial coating technology that limit its application, including the use of ultraviolet light (UV), degradation of polymeric coatings with time, and toxicity and ineffectiveness of the coatings in low-lighting conditions. The proposed research will develop a non-toxic coating offering improved viricidal activity with white light, by modifying the photocatalyst and coating, enhancing the performance in low-light environments, and exploiting chemical synergistic interactions between the coating and commonly used liquid disinfectants.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项小企业创新研究（SBIR）第一阶段项目的更广泛影响/商业潜力是开发新工具，以减少SARS-CoV-2病毒和相关的COVID-19大流行的传播。本项目开发的材料平台将有助于控制和预防病毒、细菌和其他可能引起大流行的病原体的表面传播。该项目将推进一种坚固耐用的涂层，可在使用点涂抹，以减少COVID-19的面对面传播。这项技术可能有助于减少患者和护理人员之间的感染传播。该SBIR一期项目建议开发耐用无毒的杀毒涂层，该涂层包含可见光刺激的光催化材料和坚固的聚合物基质中的暗活性材料。室内光线激活持续的抗病原菌作用；深色活性物质在日常清洁之间提供消毒物质。这种涂层将使SARS-CoV-2等病毒以及其他细菌和细菌孢子失效。这些目标克服了当前抗菌涂层技术限制其应用的主要缺点，包括使用紫外线（UV），聚合物涂层随时间降解以及涂层在低光照条件下的毒性和无效性。该研究将通过改进光催化剂和涂层，增强在弱光环境下的性能，并利用涂层与常用液体消毒剂之间的化学协同作用，开发一种无毒涂层，提高白光下的杀毒活性。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。