SBIR Phase I: Mitigating the effects of isolation and absence of therapies through the delivery of cloud based digital treatments and remote patient monitoring

SBIR 第一阶段：通过提供基于云的数字治疗和远程患者监控来减轻隔离和缺乏治疗的影响

• 批准号: 2036451
• 负责人: Bennett Gatto
• 金额: $ 25.6万
• 依托单位: Active Therapy Systems LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-01 至 2022-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2036451&HistoricalAwards=false
• 关键词: SBIR; Phase; Mitigating; effects; isolation

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to improve the quality of life for the more than 1 million Americans currently suffering from Parkinson’s Disease (PD) while reducing the growing economic burden on the healthcare system. Outpatient physical and occupational therapy, speech therapy, and mental health are key components in the treatment and management of PD. Early intervention and appropriate symptomatic management utilizing these therapies is essential for best long-term outcomes; Inadequate and infrequent treatment, especially during the COVID-19 pandemic, places a heavier burden on Person with Parkinson’s (PwP) and their families and a greater financial burden on the healthcare system. Delivering remote therapies and monitoring performance via the proposed in-home therapy platform may demonstrate a reduction in symptoms or slowing of disease progression, thereby helping to reduce costly, adverse medical complications and improving the PwP quality of life. Data collected from regular in-home, daily therapies may lead to improved standards of care and aid the research community in the search for a cure. Once proven effective in the beachhead market of PD, the technology could be trialed in the mainstream markets of Alzheimer’s, Dementia, and the aging population. This Small Business Innovation Research (SBIR) Phase I project will develop a prototype for an automated therapy delivery and remote patient monitoring platform for those suffering from Parkinson’s Disease (PD). This automated platform will provide access to daily therapies for the Person with Parkinson’s (PwP) by facilitating remote therapeutic exercise and social engagement via an in-home device that monitors real-time functionality to adapt cloud based digital content to optimize physical performance, cognition, and physiological response to exercise and cognitive tasks. Such a therapeutic system should have similar levels of efficacy as in-person therapy and treatment sessions, enabling participation in the much needed therapies while simultaneously reducing the burdens placed on the PwP, their families, and the healthcare system. The subjective report data, physiological response data, and objective performance data collected throughout each session will be summarized in a report for the PwP, their families, and their caregivers or healthcare providers to improve the continued delivery of treatment, clinical decision making, and health and safety of the patient. This proposed technology will help to reduce the effects of isolation, provide access to physical therapy and exercise treatments and improve the remote monitoring of patients throughout the COVID-19 pandemic crisis and beyond.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项小型企业创新研究（SBIR）第一阶段项目的更广泛影响/商业潜力是改善目前患有帕金森病（PD）的100多万美国人的生活质量，同时减轻医疗保健系统日益增长的经济负担。门诊物理和职业治疗，语言治疗和心理健康是PD治疗和管理的关键组成部分。利用这些疗法进行早期干预和适当的对症管理对于获得最佳长期结果至关重要;治疗不足和不频繁，特别是在COVID-19大流行期间，给帕金森氏症患者（PwP）及其家人带来了更沉重的负担，也给医疗保健系统带来了更大的经济负担。通过拟议的家庭治疗平台提供远程治疗和监测性能可能会减少症状或减缓疾病进展，从而有助于减少昂贵的不良医疗并发症并改善PwP生活质量。从定期的家庭日常治疗中收集的数据可能会提高护理标准，并帮助研究界寻找治愈方法。一旦在PD的滩头市场证明有效，该技术就可以在阿尔茨海默氏症，痴呆症和老龄化人口的主流市场中试用。该小型企业创新研究（SBIR）第一阶段项目将为帕金森病（PD）患者开发自动治疗交付和远程患者监测平台的原型。该自动化平台将通过家庭设备促进远程治疗锻炼和社交参与，从而为帕金森氏症患者（PwP）提供日常治疗，该设备监控实时功能，以适应基于云的数字内容，从而优化身体表现，认知以及对锻炼和认知任务的生理反应。这种治疗系统应具有与面对面治疗和疗程相似的疗效水平，使患者能够参与急需的治疗，同时减轻PwP、其家人和医疗保健系统的负担。每次治疗期间收集的主观报告数据、生理反应数据和客观表现数据将汇总在一份报告中，供PwP、其家人及其护理人员或医疗保健提供者使用，以改善治疗的持续提供、临床决策以及患者的健康和安全。这项拟议中的技术将有助于减少隔离的影响，提供物理治疗和运动治疗的机会，并在整个COVID-19大流行危机期间及以后改善对患者的远程监控。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。