CAREER: Multimodal Single Entity Electrochemistry at Nanoscale Liquid/Liquid Interfaces

职业：纳米级液/液界面的多模态单实体电化学

• 批准号: 2046363
• 负责人: Jiyeon Kim
• 金额: $ 60.75万
• 依托单位: University of Rhode Island
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2026-04-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2046363&HistoricalAwards=false
• 关键词: CAREER; Multimodal; Single; Entity; Electrochemistry

With support from the Chemical Measurement and Imaging Program in the Division of Chemistry, and co-funding from the Established Program to Stimulate Competitive Research, Dr. Jiyeon Kim and her group at the University of Rhode Island are developing new experimental strategies to advance our understanding of electrochemistry occurring on very small spatial scales (nanometer) in nanoemulsions (NEs) and nanopipettes. The work addresses important processes that occur at liquid/liquid interfaces, and seeks to elucidate the relationship between interfacial structure, function, and activity of these nano-objects. The long-range aim is to advance practical applications for rational and ultrasensitive analysis in diverse fields, including environmental monitoring, clinical diagnosis, and electrochemical energy storage/conversion. Dr. Kim's group works to communicate the underlying nanoscience and its importance to the general public through educational and outreach activities that seek to explain the principles of nanoelectrochemistry at the liquid/liquid interface to undergraduate and high school students with a focus on women and other groups underrepresented in science-technology-engineering-mathematics (STEM) fields.With this award, Dr. Kim's group at the University of Rhode Island is developing new experimental approaches to investigating ion- or electron-transfer (IT or ET) reactions across immiscible liquid/liquid interfaces in two distinct nanoscale domains - nanoemulsions (NEs) and nanopipettes. The work seeks to enable better practical applications through greater fundamental understanding. Specifically, a new experimental approach of multimodal single-entity electrochemistry (SEE) is being used to obtain unequivocal kinetic and thermodynamic insights at nanoscale liquid/liquid interfaces of individual NEs or nanopipettes, thereby enhancing fundamental understanding of how the associated heterogeneous IT or ET reactions are affected by the structure, thermodynamic selectivity, and contamination of the interfacial surfaces. These emerging nanoscale platforms are envisioned to provide ultrasensitive analysis with high selectivity in diverse practical applications in environmental monitoring, clinical diagnosis, and electrochemical energy storage/conversion. Advances may lead to implementation of nanoelectrochemistry in industrial settings, including mass production of commercially marketed NEs in food/drug/cosmetic industries.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在化学系化学测量和成像计划的支持下，以及刺激竞争性研究计划的共同资助下，罗德岛大学的Jiyeon Kim博士和她的团队正在开发新的实验策略，以促进我们对纳米乳剂(NE)和纳米管中发生的极小空间尺度(纳米)电化学的理解。这项工作解决了发生在液/液界面上的重要过程，并试图阐明这些纳米物体的界面结构、功能和活性之间的关系。其长期目标是促进合理和超灵敏分析在不同领域的实际应用，包括环境监测、临床诊断和电化学能量存储/转换。Kim博士的团队致力于通过教育和推广活动向公众传播潜在的纳米科学及其重要性，这些活动试图向本科生和高中生解释液/液界面的纳米电化学原理，重点关注女性和其他在科学-技术-工程-数学(STEM)领域未被充分代表的群体。凭借这一奖项，罗德岛大学的Kim博士的团队正在开发新的实验方法，以研究两个不同纳米尺度领域中不相容的液/液界面上的离子或电子转移(IT或ET)反应-纳米乳剂(NE)和纳米管。这项工作旨在通过更多的基本了解，使更好的实际应用成为可能。具体地说，一种新的多模单实体电化学实验方法(SEE)正被用来在单个NE或纳米管的纳米级液/液界面上获得明确的动力学和热力学见解，从而加强对相关的非均相IT或ET反应如何受结构、热力学选择性和界面表面污染的影响的基本理解。这些新兴的纳米级平台有望在环境监测、临床诊断和电化学能量存储/转换等各种实际应用中提供高选择性的超灵敏分析。进展可能导致纳米电化学在工业环境中的实施，包括在食品/药品/化妆品行业中大规模生产商业化的NE。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Mechanistic Assessment of Metabolic Interaction between Single Oral Commensal Cells by Scanning Electrochemical Microscopy.

通过扫描电化学显微镜对单个口腔共生细胞之间的代谢相互作用进行机制评估。

• DOI: 10.1021/acs.analchem.3c01498
• 发表时间: 2023
• 期刊: Analytical chemistry
• 影响因子: 7.4
• 作者: Puri,SurendraR;Almeida,Eric;Elangovan,Subhashini;Labossiere,Alex;Collins,Cybele;Ramsey,Matthew;Kim,Jiyeon
• 通讯作者: Kim,Jiyeon

Bacterial multispecies interaction mechanisms dictate biogeographic arrangement between the oral commensals Corynebacterium matruchotii and Streptococcus mitis.

• DOI: 10.1128/msystems.00115-23
• 发表时间: 2023-10-26
• 期刊: mSystems
• 影响因子: 6.4

Nanoscale Carbonate Ion-Selective Amperometric/Voltammetric Probes Based on Ion–Ionophore Recognition at the Organic/Water Interface: Hidden Pieces of the Puzzle in the Nanoscale Phase

基于有机/水界面离子-离子载体识别的纳米级碳酸盐离子选择性电流/伏安探针：纳米级阶段谜题的隐藏部分

• DOI: 10.1021/acs.analchem.2c02626
• 发表时间: 2023
• 期刊: Analytical Chemistry
• 影响因子: 7.4
• 作者: Elangovan, Subhashini;Puri, Surendra Raj;Madawala, Hiranya;Pantano, Justin;Pellock, Brett;Kiesewetter, Matthew K.;Kim, Jiyeon
• 通讯作者: Kim, Jiyeon