REU Site: Catalysis and Motion

REU 网站：催化和运动

• 批准号: 2050927
• 负责人: Squire Booker
• 金额: $ 37.63万
• 依托单位: Pennsylvania State Univ University Park
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2050927&HistoricalAwards=false
• 关键词: REU; Site; Catalysis; Motion

This Research Experiences for Undergraduates (REU) site award to The Pennsylvania State University, located in University Park, PA, supports the training of 10 undergraduate students for 10 weeks during the summer months of 2021-2023. The motivation for this program, funded by the Division of Chemistry, is the recognition that hands-on research experience at an early stage has an enduring impact on students' careers and the development of their science identities. Students will be recruited nationwide, with a strong emphasis on students from underrepresented and underserved groups. Each student is supervised by a faculty mentor, and the program structure provides opportunities for cross-collaboration with students and faculty in other research groups in the department and across the university. Students will work daily on their research projects, attend weekly research seminars, participate in professional development workshops and outreach events, and deliver research presentations at a cross-campus symposium. Interactions with professional industrial chemists are planned, including site visits to companies and seminars from industrial scientist to give students career information and inspiration. Formative and summative assessment is conducted, and students' careers are tracked during and after their participation. The goal is to help, inspire, and retain undergraduate students in scientific careers by providing them with a strong educational, mentoring, and research training experience.Many of the leading global scientific challenges require a deeper understanding both in biological and in chemical catalysis, and the subsequent or parallel ability to evolve new and better catalysts. Moreover, the ability to manipulate or regulate biological catalysts within human cells is the foundation of current therapeutics for a multitude of diseases. Students are recruited to work in the following areas: (1) Understanding Macromolecular Catalysis, which focuses on understanding how protein enzymes, protein metalloenzymes, and RNA enzymes catalyze reactions; (2) Dynamics of Biological Processes, which focuses on (a) understanding how protein movement or "dynamics" relates to enzyme catalysis, (b) molecular motors, and (c) the movement or "trafficking" of various types of macromolecules and small molecules within the cell and (3) New Insights into Chemical Catalysis, which involves the synthesis and characterization of chemical catalysts for a variety of processes. Coupling frontline research with professional development activities, this site aims to prepare a diverse pipeline of students ready to tackle pressing and relevant scientific problems.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

位于宾夕法尼亚州大学园区的宾夕法尼亚州立大学获得了本科生研究体验(REU)现场奖，该奖项支持在2021-2023年夏季对10名本科生进行为期10周的培训。这个由化学系资助的项目的动机是认识到，在早期阶段的实践研究经验对学生的职业生涯和他们科学身份的发展具有持久的影响。学生将在全国范围内招生，重点是来自代表性和服务不足群体的学生。每个学生都由一名教师导师监督，项目结构提供了与系内和整个大学其他研究小组的学生和教师进行交叉协作的机会。学生们将每天致力于他们的研究项目，参加每周的研究研讨会，参加专业发展研讨会和外展活动，并在跨校园研讨会上发表研究报告。计划与专业工业化学家进行互动，包括实地访问公司和工业科学家的研讨会，为学生提供职业信息和灵感。进行形成性和终结性评估，并跟踪学生在参与期间和之后的职业生涯。其目标是通过为本科生提供强大的教育、指导和研究培训经验，帮助、激励和留住本科生在科学职业生涯中。许多领先的全球科学挑战需要对生物和化学催化有更深入的理解，以及随后或平行地进化出新的和更好的催化剂的能力。此外，操纵或调节人体细胞内生物催化剂的能力是目前治疗多种疾病的基础。招收学生从事以下领域的工作：(1)了解大分子催化，重点是了解蛋白质酶、蛋白质金属酶和RNA酶如何催化反应；(2)生物过程动力学，重点是(A)了解蛋白质运动或“动力学”如何与酶催化有关，(B)分子马达，(C)各种类型的大分子和小分子在细胞内的运动或“运输”，(3)化学催化的新见解，涉及各种过程的化学催化剂的合成和表征。该网站将一线研究与专业发展活动结合起来，旨在为准备解决紧迫和相关科学问题的学生提供多样化的渠道。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。