Training the Skilled Biomanufacturing Workforce Through Innovative Internships in Protein Biomanufacturing

通过蛋白质生物制造创新实习培训熟练的生物制造劳动力

• 批准号: 2100575
• 负责人: Aron Kamajaya
• 金额: $ 52.03万
• 依托单位: Los Angeles Pierce College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2100575&HistoricalAwards=false
• 关键词: Training; Skilled; Biomanufacturing; Workforce; Through

Due to rapid growth in the biotechnology industry, the demand for skilled biotechnicians in the Los Angeles region continues to increase. Out of the ~3,200 projected annual openings in biotechnology-related jobs, more than 2,000 require an associate degree or less. The most recent statewide data indicate a massive gap in availability of these trained biotechnicians, with an annual average production in Los Angeles county of only ~50 individuals. The largest demand is for quality control and manufacturing technicians. This project will help fill this demand by providing comprehensive training and internships in biomanufacturing, a process that uses cells (or parts of cells) to produce useful products such as proteins. The biotechnology industry is one of the sectors that has been most resilient and least impacted by the COVID-19 pandemic. In contrast, people from the communities served by the college, including students who are Hispanic, have been disproportionately impacted by the pandemic. By training biomanufacturing technicians, this project will help put people back to work in more secure, well-paying jobs, and contribute to mitigating the financial impacts of COVID-19 on these individuals.This project aims to address major regional needs for biotechnology talent by establishing a protein biomanufacturing training program. By accomplishing this goal, the project will provide a pipeline for students from high school to two-year college, and then to employment or transfer to a four-year biomanufacturing program. To create the program, three new courses will be developed, implemented, and evaluated. Complementing the coursework, the project will establish a student-centered Contract Manufacturing Organization that will provide internship opportunities for students in protein biomanufacturing. The protein (Taq polymerase) will be produced by student interns working in college laboratories, and provided at low cost to local high school and community college bioscience classrooms, as well as to national course-based undergraduate research experiences programs, including the DNA Learning Center’s DNA Barcoding experience and the Amgen Biotech Experience. By providing affordable enzymes to bioscience classrooms in less-resourced institutions, the project can help mitigate COVID-19 impacts on the institutions and support greater learning opportunities for the students they serve. This project is funded by the Advanced Technological Education program that focuses on the education of technicians for the advanced-technology fields that drive the nation’s economy.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

由于生物技术产业的快速增长，洛杉矶地区对熟练生物技术人员的需求持续增加。在每年约3，200个生物技术相关工作岗位的预计空缺中，超过2，000个需要副学士学位或更少。最新的全州数据表明，这些训练有素的生物技术人员的可用性存在巨大缺口，洛杉矶县的年平均产量仅为约50人。最大的需求是质量控制和制造技术人员。该项目将通过提供生物制造方面的全面培训和实习来帮助满足这一需求，生物制造是一种使用细胞（或细胞的一部分）生产有用产品（如蛋白质）的过程。 生物技术行业是最具弹性、受COVID-19大流行影响最小的行业之一。相比之下，来自学院服务的社区的人，包括西班牙裔学生，受到了大流行病的不成比例的影响。 通过培训生物制造技术人员，该项目将帮助人们重返工作岗位，获得更安全、更高薪的工作，并有助于减轻COVID-19对这些人的经济影响。该项目旨在通过建立蛋白质生物制造培训计划，满足区域对生物技术人才的主要需求。通过实现这一目标，该项目将为学生提供从高中到两年制大学的管道，然后就业或转入四年制生物制造课程。为了创建该计划，将开发，实施和评估三门新课程。作为课程的补充，该项目将建立一个以学生为中心的合同制造组织，为学生提供蛋白质生物制造的实习机会。该蛋白质（Taq聚合酶）将由在大学实验室工作的学生实习生生产，并以低成本提供给当地高中和社区学院生物科学教室，以及国家课程为基础的本科生研究经验计划，包括DNA学习中心的DNA条形码经验和安进生物技术经验。通过向资源较少的机构的生物科学教室提供负担得起的酶，该项目可以帮助减轻COVID-19对机构的影响，并为其服务的学生提供更多的学习机会。该项目由先进技术教育计划资助，该计划侧重于为推动国家经济的先进技术领域培养技术人员。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。