Endoscopy of trabecular bone for intraoperative registration

骨小梁内窥镜检查用于术中登记

• 批准号: 246361443
• 负责人: Dr.-Ing. Lüder Alexander Kahrs
• 金额: --
• 依托单位: University of Toronto Mississauga
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2014
• 资助国家: 德国
• 起止时间: 2013-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/246361443?language=en
• 关键词: Endoscopy; trabecular; bone; intraoperative; registration

The project iBoneRegistration explores endoscopy of trabecular bone structures (cancellous bone) for intraoperative registration in navigated bone surgery. Trabecular bone is optimally suited as features for establishing the spatial transformation between preoperative image data and the intraoperative situation thanks to the unique structural composition. This enables intraoperative registration without artificial landmarks or additional intraoperative radiation-intensive imaging as commonly used nowadays. iBoneRegistration investigates: (1) Algorithms for registration based on endoscopic images of trabecular bone and preoperative medical images using the drill hole wall. (2) Endoscopy techniques for in-situ acquisition of trabecular bone in drill holes. Besides medical grade endoscopes further technical optics are developed. (3) Clinical evaluation of trabecular bone endoscopy and registration methods exemplary for otology and orthopedics. The project extension deals with (A) Investigations on registration accuracy and performance for establishment of applicability and clinical acceptance and its optimization. (B) Correction of drill pose based on preoperative planning and the registered drill pose. Both new topics allow to move the actual investigations to a status where this technique will be useful inside the operating room.

iBoneRegistration项目探索了骨小梁结构（松质骨）的内窥镜检查，用于导航骨手术中的术中配准。由于独特的结构组成，骨小梁最适合作为用于建立术前图像数据和术中情况之间的空间转换的特征。这使得术中配准无需人工标志或额外的术中辐射密集成像，如现在常用的。iBoneRegistration调查：（1）基于骨小梁的内窥镜图像和使用钻孔壁的术前医学图像的配准算法。(2)在钻孔中原位采集骨小梁的内窥镜技术。除了医用级内窥镜外，还开发了其他技术光学器件。(3)骨小梁内窥镜检查和配准方法在耳科和矫形外科中的临床评价。项目扩展涉及（A）配准准确性和性能的研究，以确定适用性和临床可接受性及其优化。(B)根据术前计划和配准的钻头姿态校正钻头姿态。这两个新的主题允许将实际调查转移到这种技术在手术室内有用的状态。

项目成果

Usefulness of a z-score-based analysis of the temporal horn volume of the lateral ventricle for detection of early Alzheimer’s disease on CT images

基于 z 分数的侧脑室颞角体积分析对于 CT 图像检测早期阿尔茨海默病的有用性

• DOI: 10.1007/s11548-016-1412-5
• 发表时间: 2016
• 期刊: Int J CARS
• 作者: Takahashi;N.;Kinoshita T.;Ohmura T.;Lee Y.;Matsuyama E.;Toyoshima H.
• 通讯作者: Toyoshima H.

Panorama imaging for image-to-physical registration of narrow drill holes inside spongy bones

全景成像，用于海绵骨内狭窄钻孔的图像到物理配准

• DOI: 10.1117/12.2254417
• 发表时间: 2017
• 作者: Bergmeier J;Fast JF;Ortmaier T;Kahrs LA
• 通讯作者: Kahrs LA

Workflow and simulation of image-to-physical registration of holes inside spongy bone

• DOI: 10.1007/s11548-017-1594-5
• 发表时间: 2017-08-01
• 期刊: INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY
• 影响因子: 3
• 作者: Bergmeier，Jan;Fitzpatrick，J. Michael;Kahrs，Lueder A.
• 通讯作者: Kahrs，Lueder A.