2021 RNA Editing Gordon Research Seminar

该奖项将支持研究生和博士后研究人员参加2021年戈登RNA编辑研究研讨会(GRS)(2021年7月31日至8月1日在加利福尼亚州文图拉海滩举行)。GRS将在相关的戈登研究会议(GRC；2021年8月1日至6日)之前举行。这两次会议汇集了来自多个学科的年轻和成熟的科学家，他们正在讨论有关核酸修饰的广泛问题，从机制和功能到生物工程工具的开发。特别是GRS，使早期职业科学家的不同群体能够通过研讨会和海报会议讨论当前的研究，非正式地交流新的想法、技术和资源，并发展他们的专业网络。因此，这次会议将促进下一代科学家的培训和专业发展，包括在核苷酸编辑领域代表人数不足的少数群体。GRS项目包括与不同专业的有成就的科学家就职业选择进行小组讨论。对于博士生的联合主席和组织者来说，GRS也是一种职业发展经验。在RNA和DNA中发现的核苷的修饰已经知道很多年了；然而，用于检测它们的新颖和灵敏的分析技术的出现，以及对它们对基本生物过程广泛影响的新认识，导致了该领域的复兴。GRS和GRC是世界各地的研究人员分享他们最新的、往往未发表的发现、讨论开创性想法和开展新合作的重要纽带。该奖项将涵盖该领域的前沿课题，包括编辑和修饰系统的进化、结构/动力学和机制，识别核酸修饰的新工具，以及设计新的核酸修饰系统等。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

The award will provide support for graduate students and post-doctoral researchers to attend the 2021 Gordon Research Seminar (GRS) on RNA Editing (July 31-Aug 1, 2021 in Ventura Beach, CA). The GRS will be held just prior to the associated Gordon Research Conference (GRC; Aug 1-6, 2021). These two meetings bring together young and established scientists from multiple disciplines who are addressing a broad range of questions about nucleic acid modifications, from mechanisms and functions to development of bioengineering tools. The GRS in particular enables a diverse group of early career scientists to discuss current research through seminars and poster sessions, exchange new ideas, technologies and resources informally, and develop their professional network. Hence this conference will facilitate training and professional development of the next generation of scientists, including underrepresented minorities, in the field of nucleotide editing. The GRS program includes a panel discussion on career choices with accomplished scientists in different professions. The GRS also serves as a career development experience for the co-chairs and organizers who are PhD students.Modifications of nucleosides found in RNA and DNA have been known for many years; however, the advent of novel and sensitive analytical techniques for their detection, and new appreciation of their broad impact on fundamental biological processes, have led to a renaissance in the field. The GRS and GRC serve as a vital link for investigators around the world to share their latest, often unpublished discoveries, discuss pioneering ideas and launch new collaborations. Topics at the forefront of the field will be covered, including the evolution, structure/dynamics and mechanisms of editing and modification systems, new tools for identification of nucleic acid modifications, and engineering new nucleic acid modification systems, among others.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.