MRI: Acquisition of Advanced Solid-State NMR Instrumentation to Investigate Novel Biological & Engineered Materials at CCNY

该奖项由主要研究仪器项目和化学研究仪器项目共同支持。纽约州立大学城市学院(CCNY)正在升级固态核磁共振(SsMRI)光谱仪的控制台，该控制台配备了用于固态核磁共振实验的先进控制系统和脉冲场高梯度(PFG)核磁共振宽带扩散探头。该仪器支持露丝·斯塔克教授、罗伯特·梅辛格教授和其他同事的研究。这种光谱仪允许在各种领域进行研究，例如那些加速具有重大经济意义的化学反应的领域，以及允许研究化学和生物相关的物种。总的来说，核磁共振波谱是化学家用来阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。该仪器是该机构化学和生物化学的本科生和研究生以及来自邻近大学的合作者的教学、研究和研究培训的组成部分。CCNY的这种先进的固态核磁共振仪器促进了针对天然和设计材料的分子生物物理学家和化学工程师之间的新合作，为分享技术专长、种子伙伴关系和传播科学进步的活动奠定了基础。该仪器还用于教育活动，如在CCNY单核磁共振用户中举办半天研讨会，分享技术专长，说明研究应用并培养学生沟通技能。一年一度的核磁共振海报会议汇聚了来自纽约市地区的核磁共振从业人员，以及使用核磁共振项目的实践外展研讨会，以激发本科生对STEM的兴趣，特别是那些来自代表不足的群体的学生。核磁共振光谱仪的获奖旨在加强各级的研究和教育。尤其是对保护细胞的颜料和聚酯的研究，以及对无机电池材料的分子环境和结构的研究。该仪器还用于研究复杂生物膜中的脂类和膜蛋白，以及研究设计的和天然的弹性蛋白纤维的张力依赖动力学，这些纤维是细胞外基质的重要组成部分。此外，该仪器允许研究用于电池的分子有机电极材料中的离子存储，并允许研究蛋白质介导的信号。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. CUNY City College (CCNY) is upgrading a console for solid state nuclear magnetic resonance (ssNMR) spectrometer that is equipped with an advanced control system for solid-state NMR experiments and a pulsed field high-gradient (PFG) NMR broadband diffusion probe. The instrument supports the research of Professor Ruth Stark, Robert Messinger and other colleagues. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as permitting study of chemically and biologically relevant species. In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution as well as collaborators from neighboring colleges. This advanced solid-state NMR instrumentation at CCNY facilitates new collaborations among molecular biophysicists and chemical engineers who target both natural and designed materials, laying the groundwork for activities that share technical expertise, seed partnerships and disseminate scientific advances. This instrument is also employed in educational activities such as half-day workshops among CCNY ssNMR users that share technical expertise, illustrate research applications and foster student communication skills. An annual NMR poster session brings together ssNMR practitioners from the NYC region and a hands-on outreach workshop using ssNMR projects to spark the interest of undergraduate students in STEM, especially those from underrepresented groups.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially impacts investigations on pigments and polyesters that protect cells and studies of molecular environments and structures of inorganic battery materials. The instrumentation is also used to enable the study of lipids and membrane proteins in complex biomembranes and the study of tension-dependent dynamics in designed and natural elastin fibers which are an essential component of extracellular matrices. In addition, it the instrument allows investigations of ion storage in molecular organic electrode materials for use in batteries, and allows studies of protein-mediated signaling.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.