NMHU-BioPACIFIC MIP collaboration in design, synthesis and applications of metal-organic hybrid biomaterials

NMHU-BioPACIFIC MIP 在金属有机杂化生物材料的设计、合成和应用方面的合作

基本信息

  • 批准号:
    2122108
  • 负责人:
  • 金额:
    $ 379.9万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Continuing Grant
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-07-01 至 2027-06-30
  • 项目状态:
    未结题

项目摘要

New Mexico Highlands University (NMHU) is a small liberal arts university in Northern New Mexico. It has a student body composed of 53.6% Hispanic Americans and 66.4% women. Many of these students are from low-income first-generation college families. This proposal presents a partnership with the NSF-supported BioPolymers, Automated Cellular Infrastructure, Flow, and integrated Chemistry Materials Innovation Platform (BioPACIFIC MIP) at University of California, Santa Barbara (UCSB) and University of California, Los Angeles (UCLA). Faculty in chemistry, biochemistry, computer science, geology, and chemical engineering will provide materials science education and hands-on training for research to students from underrepresented groups. The Partnership in Research and Education for Materials (PREM) pathway, developed with collaborative efforts from NMHU, UCSB and UCLA, will focus on recruitment, retention, and degree attainment for the students. Professional development for students will take place throughout the year both at NMHU as well as in the BioPACIFIC MIP Summer School. At BioPACIFIC MIP PREM students will have networking opportunities at multiple levels including with community leaders, faculty, staff, graduate students, and postdocs as well as peer-to-peer. The NMHU–BioPACIFIC MIP PREM will systematically engage high school students, undergraduates, graduate students, and postgraduates at all partner institutions. In New Mexico, at the high school level, the PREM will utilize dual credits for high school students and the Achieving in Research, Mathematics and Science (ARMAS) Center to encourage and engage students from underrepresented groups in science education programs. At NMHU, in collaboration with BioPACIFIC MIP, two new materials science courses, devoted to an in-depth understanding of materials structure and properties, will be designed. The PREM program will involve at least 12 BS or MS NMHU PREM students per year. The research outcome will be disseminated through publications, with a goal of at least 10 articles per year in peer reviewed journals with student co-authors in at least 80% of those publications. This project is partially supported with co-funding from the Established Program to Stimulate Competitive Research (EPSCoR).The proposed research will include machine learning, materials synthesis, high-throughput automated chemistry/biosynthesis, and applications of organic-inorganic materials. By bridging machine learning and synthetic chemistry (closing the design loop), a wider combination of bioinspired building blocks will be designed to go beyond the current biomaterial landscape. This will enable the use of two or more organic/inorganic components in one material which is necessary to tune structural, optical, electronic, and magnetic properties of a multi-component material. Resultant small molecules, organic polymers, and organic-inorganic porous materials will also allow for designing of biosensors, drug delivery systems, materials for chiral chromatography and templates for polymerization. The partnership between NMHU and BioPACIFIC MIP will allow NMHU re-searchers and students to establish a new area of materials research at NMHU. Development of new expertise will be supported by access of NMHU faculty, postdoctoral fellows and students to scientific expertise and advanced instrumentation at BioPACIFIC MIP to rapidly accelerate discovery of materials. The collaborative teams will hold research-focused group meetings via real-time video teleconferencing. Students will visit BioPACIFIC MIP laboratories. Two to three NMHU undergraduates will travel to BioPACIFIC MIP each year for summer research. One or more NMHU MS students will go to BioPACIFIC MIP to take courses and do research for one semester, and a PREM Annual Retreat will be held each year, alternating between NMHU and UCSB.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
新墨西哥州高地大学(英语:Highlands University,缩写:NMHU)是一所位于新墨西哥州北方的小型文科大学。它有一个由53.6%的西班牙裔美国人和66.4%的女性组成的学生团体。这些学生中有许多来自低收入的第一代大学生家庭。该提案与加州大学圣巴巴拉分校(UCSB)和加州大学洛杉矶分校(UCLA)的NSF支持的生物聚合物、自动化细胞基础设施、流动和综合化学材料创新平台(BioPACIFIC MIP)建立了合作关系。化学,生物化学,计算机科学,地质学和化学工程学院将为来自代表性不足群体的学生提供材料科学教育和实践培训。材料研究和教育伙伴关系(PREM)途径,与NMHU,UCSB和UCLA的合作努力开发,将专注于学生的招聘,保留和学位获得。学生的专业发展将在NMHU和BioPACIFIC MIP暑期学校全年进行。在BioPACIFIC MIP PREM,学生将在多个层面上获得网络机会,包括与社区领袖,教师,员工,研究生和博士后以及点对点。NMHU-BioPACIFIC MIP PREM将系统地吸引所有合作机构的高中生,本科生,研究生和研究生。在新墨西哥州,在高中一级,PREM将利用高中学生的双学分和研究、数学和科学成就(ARMAS)中心,鼓励和吸引来自代表性不足群体的学生参加科学教育方案。在NMHU,与BioPACIFIC MIP合作,将设计两门新的材料科学课程,致力于深入了解材料结构和性能。PREM计划将涉及每年至少12个BS或MS NMHU PREM学生。研究成果将通过出版物传播,目标是每年在同行评审期刊上发表至少10篇文章,其中至少80%的出版物由学生合著。该项目部分由刺激竞争研究的既定计划(EPSCoR)共同资助。拟议的研究将包括机器学习,材料合成,高通量自动化化学/生物合成以及有机-无机材料的应用。通过桥接机器学习和合成化学(关闭设计循环),将设计出更广泛的生物启发构建块组合,以超越当前的生物材料领域。这将使得能够在一种材料中使用两种或更多种有机/无机组分,这对于调节多组分材料的结构、光学、电子和磁性是必要的。所得的小分子、有机聚合物和有机-无机多孔材料也将允许设计生物传感器、药物递送系统、用于手性色谱的材料和用于聚合的模板。NMHU和BioPACIFIC MIP之间的合作伙伴关系将使NMHU研究人员和学生能够在NMHU建立一个新的材料研究领域。新的专业知识的发展将通过NMHU教师,博士后研究员和学生获得BioPACIFIC MIP的科学专业知识和先进仪器来支持,以快速加速材料的发现。合作团队将通过实时视频电话会议举行以研究为重点的小组会议。学生将参观BioPACIFIC MIP实验室。两到三个NMHU本科生将前往BioPACIFIC MIP每年夏季研究。一名或多名NMHU MS学生将前往BioPACIFIC MIP参加课程并进行为期一个学期的研究,每年将举行PREM年度务虚会,在NMHU和UCSB之间交替。该奖项反映了NSF的法定使命,并通过使用基金会的智力价值和更广泛的影响审查标准进行评估,被认为值得支持。

项目成果

期刊论文数量(15)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Co-crystals of polynuclear aromatic hydrocarbons and 9H-carbazole with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone acceptor: varieties in crystal packing, Hirshfeld surface analysis and quantum-chemical studies
  • DOI:
    10.1016/j.molstruc.2023.134900
  • 发表时间:
    2023-01
  • 期刊:
  • 影响因子:
    3.8
  • 作者:
    M. Fonari;Sergei Rigin;Daniel Lesse;T. Timofeeva
  • 通讯作者:
    M. Fonari;Sergei Rigin;Daniel Lesse;T. Timofeeva
Distributed crustal shortening followed by transpressional shearing in the Superior Province, northeastern Canada: A Late Archean analogy to modern accretionary plate margins?
  • DOI:
    10.1016/j.precamres.2021.106322
  • 发表时间:
    2021-08
  • 期刊:
  • 影响因子:
    3.8
  • 作者:
    J. Žák;F. Tomek;M. Svojtka;F. Vacek;V. Kachlík;L. Ackerman;J. Jezek;M. Petronis
  • 通讯作者:
    J. Žák;F. Tomek;M. Svojtka;F. Vacek;V. Kachlík;L. Ackerman;J. Jezek;M. Petronis
Exploiting Supramolecular Synthons in Cocrystals of Two Racetams with 4-Hydroxybenzoic Acid and 4-Hydroxybenzamide Coformers
利用 4-羟基苯甲酸和 4-羟基苯甲酰胺共晶的两种消旋体共晶中的超分子合成子
  • DOI:
    10.3390/chemistry5020074
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Marquez, Jason;Novikov, Egor;Rigin, Sergei;Fonari, Marina S.;Castañeda, Raúl;Kornilova, Tatiana;Timofeeva, Tatiana V.
  • 通讯作者:
    Timofeeva, Tatiana V.
Magnetic fabrics of rhyolite ignimbrites reveal complex emplacement dynamics of pyroclastic density currents, an example from the Altenberg–Teplice Caldera, Bohemian Massif
  • DOI:
    10.1007/s00445-022-01577-1
  • 发表时间:
    2022-07
  • 期刊:
  • 影响因子:
    3.5
  • 作者:
    Petr Vitouš;F. Tomek;M. Petronis
  • 通讯作者:
    Petr Vitouš;F. Tomek;M. Petronis
Eruptive and magma feeding system evolution of Sośnica Hill Volcano (Lower Silesia, SW Poland) revealed from Volcanological, Geophysical, and Rock Magnetic Data
火山学、地球物理和岩石磁力数据揭示了索尼卡山火山(波兰西南部下西里西亚)的喷发和岩浆供给系统演化
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Gil Gallegos其他文献

Gil Gallegos的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Gil Gallegos', 18)}}的其他基金

RAPID: Machine Learning Methods to Understand, Predict and Reduce the Spread of COVID-19 in Small Communities
RAPID:理解、预测和减少 COVID-19 在小社区中传播的机器学习方法
  • 批准号:
    2031548
  • 财政年份:
    2020
  • 资助金额:
    $ 379.9万
  • 项目类别:
    Standard Grant

相似海外基金

MIP: BioPolymers, Automated Cellular Infrastructure, Flow, and Integrated Chemistry: Materials Innovation Platform (BioPACIFIC MIP)
MIP:生物聚合物、自动化细胞基础设施、流程和集成化学:材料创新平台 (BioPACIFIC MIP)
  • 批准号:
    1933487
  • 财政年份:
    2020
  • 资助金额:
    $ 379.9万
  • 项目类别:
    Cooperative Agreement
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了