Planning Grant: Engineering Research Center for the Next-generation Enterprise to Engineer Diagnostics at Low-cost for the home-Ecosystem (NEEDLE)

规划补助金：下一代企业工程研究中心以低成本为家庭生态系统设计诊断（NEEDLE）

• 批准号: 2124312
• 负责人: Kimani Toussaint
• 金额: $ 10万
• 依托单位: Brown University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2124312&HistoricalAwards=false
• 关键词: Planning; Grant; Engineering; Research; Center

The health-care supply chain is fragile, as illustrated by the breakdowns in care delivery experienced during COVID-19. While advances in digital health have the potential to improve the health-services supply chain, the range of available state-of-the-art health-sensor technologies for at-home patient use is minimal and severely limited in accuracy. Moreover, these sensors are limited to a common group of measures such as body temperature, blood pressure, weight, oxygen saturation, and glucose monitoring. Therefore, the technology does not exist to provide health practitioners with sufficient, remote patient diagnostic information that reasonably approximates data obtained from traditional in-person medical visits. This grant seeks to map out a vision for an Engineering Research Center (ERC) that will produce the next generation of home-health diagnostic technologies to effectively bring the medical lab and physician to the home. Thus, the project will launch specialized workshops to explore the feasibility of an NSF ERC for the Next-generation Enterprise to Engineer Diagnostics at Low-cost for the home-Ecosystem (NEEDLE). Outcomes from the workshops will be broadly disseminated via publications and conference presentations. Finally, the involvement of a postdoctoral researcher to help coordinate activities, as well as a seed competition for student teams collaborating across three universities, provides an opportunity to train the next generation of innovators in technology development. A NEEDLE ERC could spawn the development of technologies that could significantly strengthen the health-services supply chain by directly connecting every home to the digital-health ecosystem. This ERC will focus on creating a diagnostic toolkit that will provide every home with the medical equivalent of the physical exam (e.g., inspection, palpation, and percussion) and standard lab tests (e.g., complete blood count, basic metabolic, and viral load) found at a medical facility, along with an AI-enabled data infrastructure for personalized health monitoring. The highly integrated and complex nature of the problem requires a convergence of community stakeholders, and experts in areas such as biomaterial sensors, non-invasive biological imaging, micro/nanofabrication, spectroscopy, data science, micro/nanoelectronics, and advanced signal processing. The proposed planning-grant will introduce workshops aimed at bringing these communities together to produce a needs-assessment report and a 10-year roadmap of the scientific and technological breakthroughs needed to develop home diagnostics. These activities will enable the formulation of a deployment strategy to mitigate any barriers to accessibility for developed technologies, including cost and general usability, especially for populations experiencing potential age-related cognitive decline, populations without “digital native” experience with technology, or those living in zones with inadequate Wi-Fi accessibility.This project is jointly funded by the ERC Program/EEC Division of the Engineering Directorate and the Established Program to Stimulate Competitive Research (EPSCoR).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

2019冠状病毒病期间医疗服务的中断说明了医疗供应链的脆弱性。虽然数字健康的进步有可能改善医疗服务供应链，但可供家庭患者使用的最先进的健康传感器技术的范围很小，而且准确性严重有限。此外，这些传感器限于一组常见的测量，例如体温、血压、体重、氧饱和度和葡萄糖监测。因此，不存在为健康从业者提供充分的远程患者诊断信息的技术，该信息合理地近似于从传统的亲自医疗访问获得的数据。该补助金旨在规划工程研究中心（ERC）的愿景，该中心将生产下一代家庭健康诊断技术，以有效地将医疗实验室和医生带到家中。 因此，该项目将启动专门的研讨会，以探索NSF ERC为下一代企业以低成本为家庭生态系统（NEEDLE）进行工程诊断的可行性。讲习班的成果将通过出版物和会议介绍广泛传播。最后，博士后研究人员的参与，以帮助协调活动，以及在三所大学合作的学生团队的种子竞争，提供了一个机会，培养下一代的创新技术开发。 NEEDLE ERC可以促进技术的发展，通过将每个家庭直接连接到数字健康生态系统，大大加强健康服务供应链。ERC将专注于创建一个诊断工具包，为每个家庭提供相当于体检的医疗服务（例如，检查、触诊和叩诊）和标准实验室测试（例如，全血细胞计数、基本代谢和病毒载量），沿着支持AI的数据基础设施，用于个性化健康监测。该问题的高度集成和复杂性需要社区利益相关者以及生物材料传感器，非侵入性生物成像，微/纳米纤维，光谱学，数据科学，微/纳米电子学和高级信号处理等领域的专家的融合。拟议的规划补助金将引入研讨会，旨在将这些社区聚集在一起，编写需求评估报告和开发家庭诊断所需的科学和技术突破的10年路线图。这些活动将有助于制定一项部署战略，以减少任何阻碍发达技术可及性的障碍，包括成本和一般可用性，特别是对于可能出现与年龄有关的认知能力下降的人群，没有“数字原生”技术经验的人群，或那些居住在Wi-Fi接入不足的地区的人。该项目由ERC计划/工程理事会EEC部门和刺激竞争性研究的既定计划（EPSCoR）。该奖项反映了NSF的法定使命，并且通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

The Smart Cane Project: Integrating Screen Interfaces and Physiological Sensors into Mobility Devices

智能手杖项目：将屏幕界面和生理传感器集成到移动设备中

• DOI: 10.54941/ahfe1004383
• 发表时间: 2023
• 期刊: AHFE Open Access Proceedings Human
• 作者: Gonsher, Ian;Salazar, Adriana;Mehta, Shrey;Shulman, Samantha;Gaitanis, Nicholas;Khosla, Arshiya;Danielle Tamesis, Denise;Sun, Jillian
• 通讯作者: Sun, Jillian

The Mixed Reality Passthrough Window: Rethinking the Laptop Videoconferencing Experience

混合现实直通窗口：重新思考笔记本电脑视频会议体验

• DOI: 10.54941/ahfe1002954
• 发表时间: 2023
• 期刊: Accelerating Open Access Science in Human Factors Engineering and Human-Centered Computing
• 作者: Gonsher, Ian;Ma, Yumeng;Pineda-Dominguez, Ivan;Lee, Matthew;Han, Yuxin
• 通讯作者: Han, Yuxin