Emergent Properties of Cancer Square Table

癌症方桌的涌现性质

• 批准号: 2130872
• 负责人: Jennifer Schwarz
• 金额: $ 9.9万
• 依托单位: Syracuse University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-01 至 2021-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2130872&HistoricalAwards=false
• 关键词: Emergent; Properties; Cancer; Square; Table

This proposal seeks support for a Square-Table (SQT) meeting that is one of three meetings co-organized by the Division of Cancer Biology (DCB) of the National Cancer Institute (NCI) and the Mathematical and Physical Sciences (MPS) Directorate of the National Science Foundation (NSF) to explore fundamental research at the nexus of the physical sciences and mathematics, synthetic and systems biology, and cancer research. The goal of the meetings is to foster stimulating discussions between researchers whose work at the frontiers of their own discipline may not yet intersect in a substantial way yet but whose exchange of knowledge, thoughts, and ideas could identify research discoveries and directions that have high potential impact on, and may be transformative for, cancer research. This meeting, entitled SQT- Emergent Properties of Cancer, will complement the other two meetings on SQT- Living Materials and SQT- Windows on the Cell. The goal are discussion of fundamental challenges and opportunities at and over the horizon (10-15 year time frame) at the interface between fundamental sciences (typically funded by the Directorate of the Mathematical and Physical Sciences at the NSF) and cancer research (typically funded by NCI) and needed methodological developments that could enable transformative research. The outcome will be a synthesized report of the discussions and questions raised in the meeting. Along with the reports of the other two SQT meetings, these reports will provide an intellectual map of future questions and serve both NCI and NSF to understand the scientific intersections that are most interesting and important. Recent advances in the physical sciences and mathematics relevant to biology, in synthetic and systems biology, and in cancer research have highlighted the need to explore the intersection of these areas at and over the horizon, 10-15 years out, for new opportunities and identifying the gaps. This Square-Table (SQT) meeting is intended to bring together distinct and non-interacting disciplines of the fundamental sciences and math, with synthetic biology, and cancer researchers. This SQT meeting will focus on Emergent Properties of Cancer and is the third of three meetings, complementing Living Materials and Windows on the Cell SQT meetings sponsored jointly between the Division of Cancer Biology (DCB) of the National Cancer Institute (NCI) and the Mathematical and Physical Sciences (MPS) Directorate of the National Science Foundation (NSF). This SQT meeting will also initiate and foster new partnerships between groups of researchers who generally don’t interact but whose separate research endeavors can complement and foster synergistic work with strong potentially transformative impact in biotechnology and medicine. Interactions and interdisciplinary collaborations between the participants can provide a solid ground for training the next generation of scientists, engineers and researchers. The outcome will be a synthesized report of the discussions and questions raised in the meeting. Along with the reports of the other two SQT meetings, these reports will provide an intellectual map of future questions and serve both NCI and NSF to understand the scientific intersections that are most interesting and important.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该提案寻求支持方桌（SQT）会议，该会议是由国家癌症研究所（NCI）癌症生物学部（DCB）和国家科学基金会（NSF）数学和物理科学（MPS）理事会共同组织的三次会议之一，旨在探索物理科学和数学，合成和系统生物学以及癌症研究的基础研究。 会议的目标是促进研究人员之间的讨论，这些研究人员在自己学科的前沿工作可能尚未以实质性的方式交叉，但他们的知识，思想和想法的交流可以确定对癌症研究具有高度潜在影响的研究发现和方向，并可能是变革性的。 这次会议，题为SQT-癌症的紧急性质，将补充其他两个会议SQT-生活材料和SQT-细胞的窗口。 目标是讨论基础科学（通常由NSF的数学和物理科学理事会资助）和癌症研究（通常由NCI资助）之间的界面上的基本挑战和机遇，以及可以实现变革性研究的方法学发展。 会议结果将是一份关于会议讨论情况和提出的问题的综合报告。 沿着其他两次SQT会议的报告，这些报告将提供一个未来问题的知识图谱，并为NCI和NSF理解最有趣和最重要的科学交叉点提供服务。与生物学、合成生物学和系统生物学以及癌症研究相关的物理科学和数学的最新进展突出表明，有必要在未来10-15年内探索这些领域的交叉点，寻找新的机会并找出差距。 本次SQT会议旨在将基础科学和数学、合成生物学和癌症研究人员的独特和非相互作用的学科聚集在一起。 本次SQT会议将重点关注癌症的紧急特性，是三次会议中的第三次，补充了国家癌症研究所（NCI）癌症生物学部（DCB）和国家科学基金会（NSF）数学和物理科学（MPS）理事会联合赞助的细胞SQT会议的生活材料和窗口。 本次SQT会议还将启动和促进研究人员群体之间的新伙伴关系，这些研究人员通常不会互动，但其单独的研究工作可以补充和促进协同工作，对生物技术和医学产生强大的潜在变革影响。参与者之间的互动和跨学科合作可以为培养下一代科学家，工程师和研究人员提供坚实的基础。 会议结果将是一份关于会议讨论情况和提出的问题的综合报告。 沿着其他两次SQT会议的报告，这些报告将提供未来问题的知识图谱，并为NCI和NSF提供服务，以了解最有趣和最重要的科学交叉点。该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估来支持。