SBIR Phase I: Development of a nasal compression device with medicated intranasal sponges for the treatment of nosebleeds in any setting

这个小企业创新研究（SBIR）第一阶段的项目是帮助治疗普通的流鼻血。流鼻血是60%的人都会遇到的常见问题。拟议的项目开发了一种有效和低成本的创新技术，通过将任何用户以名义方式放置的外部压力与鼻内药物相结合来解决这一问题。该解决方案将提供一种简单的方法，减少患者访问卫生保健服务的需要，并减轻卫生保健提供者治疗流鼻血的负担。该项目的目标是为儿童和成人设计和开发一种有效的鼻出血治疗装置，该装置将使用原型鼻夹的外部压力与鼻内药物海绵相结合。该项目的目标包括完成系统研究：(1)设计和开发带有预用药鼻内海绵的鼻夹，该鼻内海绵能够在以标称方式放置时持续施加适量的压力并洗脱适量的药物；(2)使用鼻出血模型测试该设备；(3)确定制造工艺，以经济有效的方式将该设备商业化和规模化。结果将是一个功能和实验室测试鼻出血治疗夹。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This Small Business Innovation Research (SBIR) Phase I project is to help treat the common nosebleed. Nosebleeds are a common problem that 60% of people experience. The proposed project develops an effective and low-cost innovative technology to address this by combining external pressure with intranasal medication when placed in a nominal manner by any user. The solution would provide a simple method that reduces the need for patients to visit health care services, and reduces the burden of health care providers for treating nosebleeds. The goal of this project is to design and develop an effective nosebleed treatment device for children and adults that combines external pressure using a prototype nasal clip with intranasal medication sponges. The objectives of this project include completing systematic studies towards (1) design and development of a nasal clip with pre-medicated intranasal sponges capable of consistently applying the proper amount of pressure and eluting the proper amount of medication when placed in a nominal manner, (2) testing of the device using a nosebleed model, (3) identifying manufacturing processes to commercialize and scale the device in a cost effective manner. The outcome will be a functional and lab tested nosebleed treatment clip.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.