SBIR Phase I: Development of a nasal compression device with medicated intranasal sponges for the treatment of nosebleeds in any setting

这个小型企业创新研究(SBIR)第一阶段项目是为了帮助治疗常见的鼻血。流鼻血是60%的人都会经历的常见问题。拟议的项目开发了一种有效和低成本的创新技术来解决这一问题，方法是将外部压力与任何使用者名义上使用的鼻腔给药相结合。该解决方案将提供一种简单的方法，减少患者访问卫生保健服务的需要，并减轻卫生保健提供者治疗鼻出血的负担。该项目的目标是为儿童和成人设计和开发一种有效的鼻出血治疗装置，该装置将使用原型鼻夹和鼻腔给药海绵的外部压力相结合。该项目的目标包括完成以下方面的系统研究：(1)设计和开发一种带有预先用药的鼻腔海绵的鼻夹，该鼻夹能够持续施加适量的压力并在名义上放置时洗脱适量的药物，(2)使用鼻出血模型对该装置进行测试，(3)确定以具有成本效益的方式将该装置商业化和规模化的制造工艺。结果将是一个功能性和实验室测试的鼻出血治疗夹子。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This Small Business Innovation Research (SBIR) Phase I project is to help treat the common nosebleed. Nosebleeds are a common problem that 60% of people experience. The proposed project develops an effective and low-cost innovative technology to address this by combining external pressure with intranasal medication when placed in a nominal manner by any user. The solution would provide a simple method that reduces the need for patients to visit health care services, and reduces the burden of health care providers for treating nosebleeds. The goal of this project is to design and develop an effective nosebleed treatment device for children and adults that combines external pressure using a prototype nasal clip with intranasal medication sponges. The objectives of this project include completing systematic studies towards (1) design and development of a nasal clip with pre-medicated intranasal sponges capable of consistently applying the proper amount of pressure and eluting the proper amount of medication when placed in a nominal manner, (2) testing of the device using a nosebleed model, (3) identifying manufacturing processes to commercialize and scale the device in a cost effective manner. The outcome will be a functional and lab tested nosebleed treatment clip.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.