CAREER: Optical Super-Resolution Nanothermometry via Stimulated Emission Depletion Imaging

职业：通过受激发射损耗成像进行光学超分辨率纳米测温

• 批准号: 2142140
• 负责人: Andrea Pickel
• 金额: $ 55.02万
• 依托单位: University of Rochester
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2142140&HistoricalAwards=false
• 关键词: CAREER; Optical; Super; Resolution; Nanothermometry

We live in an era of nanotechnology, where omnipresent devices like the laptops and smart phones that power our communications, the hard drives that store our data, and the light-emitting diodes that illuminate our buildings contain a multitude of nanoscale components. Increasingly, these electronic, data storage, and energy conversion devices must also operate under challenging conditions, including extreme temperatures, high pressures, large electromagnetic fields, and harsh chemical environments. Simultaneously, thermal properties play an outsize role in determining the overall performance of these technologies. For example, poor heat dissipation can limit the reliability of electronics and hard drives, while high-performance thermal insulation materials instead must greatly reduce heat transfer. Non-invasive temperature mapping with nanoscale spatial resolution is thus critical for optimizing the performance and reliability of a wide array of modern technologies. However, most existing thermometry techniques either require physically contacting samples with a temperature probe, which can perturb the sample and preclude measurements in challenging environments, or else lack the spatial resolution needed to resolve nanoscale temperature heterogeneities. The central goal of this proposal is to address these challenges by developing a novel super-resolution nanothermometry technique, enabling far-field optical temperature mapping with sub-diffraction limited spatial resolution. The proposed technique relies on luminescent nanomaterials called upconverting nanoparticles that can operate under wide-ranging conditions and independent of sample form factor or material type. Using a custom-built imaging and spectroscopy system, the principal investigator and her research team will adapt a Nobel Prize-winning super-resolution imaging technique called stimulated emission depletion for thermometry. The team will demonstrate temperature-dependent stimulated emission depletion spectroscopy, use spatially resolved stimulated emission depletion measurements to map surface temperature profiles of microfabricated heater structures with spatial resolution down to ~60 nm, and apply stimulated emission depletion nanothermometry to uncover failure mechanisms in operating optoelectronic devices, a major challenge that cannot be fully addressed by existing techniques. In concert, the integrated education plan will democratize thermal microscopy via the creation of an open source hardware repository and help ensure full participation of the next generation of underrepresented groups in science and engineering fields through an elementary school outreach partnership.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

我们生活在一个纳米技术的时代，在这里无所不在的设备，例如笔记本电脑和智能手机，可以为我们的通信提供动力，存储数据的硬盘驱动器以及照明建筑物的发光二极管包含许多纳米级组件。这些电子，数据存储和能量转换设备的越来越多，还必须在具有挑战性的条件下运行，包括极端温度，高压力，大电磁场和恶劣的化学环境。同时，热特性在确定这些技术的整体性能中起着极高的作用。例如，散热不良会限制电子和硬盘驱动器的可靠性，而高性能的热绝缘材料则必须大大减少传热。因此，使用纳米级空间分辨率的非侵入性温度映射对于优化广泛的现代技术的性能和可靠性至关重要。但是，大多数现有的温度计技术要么需要与温度探针进行物理接触，这可能会在具有挑战性的环境中扰动样品并排除测量值，否则缺乏解决纳米级温度异质性所需的空间分辨率。 该提案的核心目标是通过开发一种新型的超分辨率纳米热计技术来应对这些挑战，从而实现远场光学温度映射，并通过二分裂有限的空间分辨率。提出的技术依赖于可发光的纳米材料，称为上转换纳米颗粒，这些纳米颗粒可以在宽范围的条件下运行，并且独立于样品形式或材料类型。使用定制的成像和光谱系统，首席研究员及其研究团队将适应诺贝尔奖获得的超分辨率成像技术，称为刺激的热度法发射消耗。该团队将展示依赖温度的刺激排放消耗光谱法，使用空间解析的发射消耗测量测量值，以绘制以空间分辨率降低到〜60 nm的微型加热器结构的表面温度剖面，并通过刺激的纳米米米进行刺激的纳米米米，以实现失败的纳米米米在操作中，无法在操作范围内进行启用，使得无法进行操作范围，以至于无法进行启用。在协同的过程中，综合教育计划将通过创建开源硬件存储库来使热显微镜民主化，并有助于确保通过小学外展合作伙伴关系在科学和工程领域的下一代人的全部代表性不足的群体的全面参与。该奖项反映了NSF的法定任务，反映了通过评估基金会的智力效果，并通过评估了基金会的范围。