Targeted Infusion Project Development of a CRISPR Cas9 based gene editing technology curriculum at Tennessee State University

历史上的黑人学院和大学本科生计划（HBCU-UP）通过有针对性的输液项目支持开发，实施和研究以证据为基础的创新模式和方法，以提高HBCU本科生的准备和成功，使他们可以追求科学，技术，工程或数学（STEM）研究生课程和/或职业。该项目旨在整合尖端的基因编辑技术，重点关注CRISPR-Cas9（重复的规则间隔短回文重复序列）为基础的基因组编辑纳入田纳西州立大学（大津）的课程，并培养一代精通基因编辑原则和道德的学生，他们将成为未来的农业政策制定者，科学家，CRISPR-Cas9课程将（1）提供一门专门的课程来培养大学生掌握这项尖端技术，（2）增加农业和生物科学研究生课程的学生入学率，以及（3）为来自其他历史上黑人学院或大学的教师提供为期两天的讲习班，以接受以下方面的培训：在大津的网站，以便他们可以适应自己的学位课程的材料。此外，活动的结果将通过出版物，会议演示文稿，并通过农业的社会媒体渠道和参与PI和高级人员的个人社交媒体帐户的大津大学传播到更广泛的社区。该项目将对农业和生物科学部门的教育和研究产生重大影响，并极大地提高学生对新兴技术的认识，为他们的研究生学习和STEM劳动力做好准备。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。

The Historically Black Colleges and Universities Undergraduate Program (HBCU-UP) through Targeted Infusion Projects supports the development, implementation, and study of evidence-based, innovative models and approaches for improving the preparation and success of HBCU undergraduate students so that they may pursue science, technology, engineering, or mathematics (STEM) graduate programs and/or careers. This project seeks to incorporate cutting-edge gene editing technologies with a focus on CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats)-based genome editing into the curriculum at Tennessee State University (TSU) and train a generation of students well-versed in the principles and ethics of gene editing, who go on to become future agricultural policy makers, scientists, and agribusiness managers in keeping with the National Science Foundation’s mission to promote the progress of science.The CRISPR-Cas9 course will (1) offer a dedicated course to train undergraduates in this cutting-edge technology, (2) increase the matriculation of students into agricultural and biological sciences graduate programs, and (3) provide a two-day workshop for faculty from other Historically Black Colleges or Universities to be trained on-site at TSU so that they can adapt the material to their own degree offerings. In addition, the results of the activities will be disseminated to the broader communities through publications, conference presentations, and via the TSU College of Agriculture social media channels and personal social media accounts of participating PIs and senior personnel. This project will have significant impact on the education and research in the agricultural and biological science departments, and greatly improve students’ knowledge in emerging technologies, better preparing them for graduate study and the STEM workforce.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.