Sustaining: A Bridge to Sustainability for the CIPRES Science Gateway

这份授予加州大学圣地亚哥分校的合同将维持系统发育研究网络基础设施（CIPRES）科学门户网站的在线存在，该网站允许来自世界各地的科学家通过访问社区软件更容易地进行发现，这些软件用于分析运行在nsf资助的大型计算集群上的复杂系统发育问题。目前，每年至少有1.2万名科学家使用CIPRES网关进行数万项工作；这些工作是对自然界和地球生命起源做出新的科学发现的重要组成部分。在过去的一年里，至少有1800项科学研究利用了ciprs的成果发表。如果没有CIPRES提供的资源，所有这些研究都将变得更加困难，甚至不可能。CIPRES使那些无法访问大型本地/校园计算资源的研究人员能够提出大问题并进行困难的调查。它还使每年有100多名教师使用世界上最好的工具培训下一代系统发育研究人员成为可能。CIPRES对基础生物学研究的影响是显著的。假设目前的趋势继续下去，CIPRES将在奖励期间支持6000多个研究。CIPRES提供的访问使科学家能够快速调查SARS-CoV-2病毒的起源和分布，强调了像CIPRES这样的资源在科学家需要对不可预见的、时间敏感的研究问题做出快速反应时的价值。在此期间，研究人员将专注于将CIPRES科学网关从nsf资助的资源转变为用户资助的资源。该项目的目标是开发工具和策略，使CIPRES科学门户能够通过项目用户和赞助商产生的收入无限期地维持下去。目前，每年有成千上万的用户访问并在CIPRES上运行作业，作为他们对地球上生命进化的科学调查的一部分。鉴于该资源对其社区具有持久的价值，研究人员将开发收入来源，以便在没有NSF或其他联邦机构额外资助的情况下永久维护和保存该资源。提议的活动包括软件维护和系统管理任务，通过支持个人用户提交的基于web的图形用户界面，以及通过支持其他科学网关和需要系统发生分析的桌面应用程序提交的RESTful应用程序编程接口，维护作业提交、结果存储和结果检索的操作完整性。其他活动将包括常规更新、基准测试和发布当前和新的社区代码；监察使用情况，以确保使用者有效及审慎地使用科学基金资源；用户支持;根据用户反馈进行调整和bug修复；报告进度。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award to the University of California - San Diego will sustain the online presence of the Cyberinfrastructure for Phylogenetic Research (CIPRES) Science Gateway, an internet site that allows scientists from around the world to make discoveries more easily through access to community software for analyzing complex phylogenetic questions run on large NSF-funded compute clusters. Currently at least 12,000 scientists run tens of thousands of jobs each year using the CIPRES Gateway; these jobs are an essential part of making new scientific discoveries about the natural world and the origin of life on Earth. In the past year at least 1,800 scientific studies were published using results made possible by CIPRES. All of these studies would have been more difficult or even impossible without the access to resources that CIPRES provides. CIPRES makes it possible for researchers who do not have access to large local/campus computing resources to ask large questions and conduct difficult investigations. It also makes it possible for more than 100 instructors each year to train the next generation of phylogenetics researchers, using the finest tools available in the world. The impact of CIPRES on basic biological research is significant. Assuming current trends continue, CIPRES will support 6,000+ studies during the award period. The access provided by CIPRES allowed scientists to quickly investigate the origin and distribution of the SARS-CoV-2 virus, emphasizing the value of a resource like CIPRES when scientists need to respond rapidly to an unforeseen, time-sensitive research problem.During this award, the researchers will focus on changing the CIPRES Science Gateway from an NSF-funded resource to a user-funded resource. The goal of the project is to develop tools and strategies that make it possible to sustain the CIPRES Science Gateway indefinitely via revenues generated from the project’s users and sponsors. At present thousands of users access and run jobs at CIPRES each year as part of their scientific investigations into the evolution of life on Earth. Given that the resource has enduring value to its community, the researchers will develop revenue streams that will allow maintenance and preservation of the resource in perpetuity without additional funding from NSF or other federal agencies. The proposed activities include software maintenance and systems administration tasks that preserve the operational integrity of job submissions, results storage, and results retrieval via a web-based graphical user interface that supports submissions by individual users, and via a RESTful application programming interface that supports submissions by other science gateways and desktop applications that require phylogenetic analyses. Additional activities will include routine updating, benchmarking, and release of current and new community codes; usage monitoring to ensure efficient and prudent use of NSF resources by the user community; user support; adjustments and bug fixes based on feedback from users; and reporting progress.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.