I-Corps: Smart Bandage for Wound Care Management

该I-Corps项目更广泛的影响/商业潜力是开发伤口监测技术，提供早期和预测性伤口状况数据，以加快治疗决策。该技术旨在远程和实时监测受伤的生理状态。该技术可以通过提供低成本且用户友好的可穿戴伤口监测设备来改善人类健康。不仅限于伤口，基于技术的直接读取检测平台还可以帮助医疗保健行业开发快速，灵敏，可重复和全自动的实时监测技术，能够检测危及生命的疾病中的生物标志物。该I-Corps项目基于开发一种用于实时和远程监测生化伤口标志物的新型设备，为患者提供个性化的医疗保健解决方案。电子传感器将内置于一个小型设备中，该设备集成在专用绷带中。该绷带由尿酸传感器（伤口愈合的生物标志物）以及pH和湿度传感器组成，以监测继发感染和细菌定植的早期迹象。该装置集成了一个微控制器和模块，用于实时数据传输和监控。该系统将使用机器学习模型来了解伤口的严重程度，提供与特定患者愈合率相关的信息。这些数据也将用于评估损伤的严重程度、最佳治疗方法和估计的恢复时间。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The broader impact/commercial potential of this I-Corps project is the development of a wound monitoring technology that provides early and predictive wound condition data to accelerate treatment decisions. The technology seeks to allow monitoring of the physiological state of injuries remotely and in real-time. The technology may improve human well-being by providing a low-cost and user-friendly, wearable, wound monitoring device. Not limited to wounds, the technology-based direct-read detection platform may also help the healthcare industry develop fast, sensitive, reproducible, and fully automated technologies for real-time monitoring capable of detecting biomarkers in life-threatening diseases. This I-Corps project is based on the development of a novel device for real-time and remote monitoring of biochemical wound markers, providing personalized health care solutions for patients. The electronic sensor will be built into a small device that is integrated in a specialized bandage. The bandage consists of a uric acid sensor (a biomarker of wound healing), as well as pH and humidity sensors to monitor secondary infections and early signs of bacterial colonization. The setup incorporates a microcontroller and module for real-time data transfer and monitoring. The system will use machine learning models to understand the severity of the wound, providing information related to the healing rate of that specific patient. The data will also be used to assess the severity of the injury, best treatment methodology, and estimated timeof recovery.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.