SBIR Phase I: PenEEG: An Objective Assessment Tool for Concussion and Recovery Management

SBIR 第一阶段：PenEEG：脑震荡和恢复管理的客观评估工具

• 批准号: 2304353
• 负责人: Ayushi Hitesh Patel
• 金额: $ 27.5万
• 依托单位: CENSYN INC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-11-15 至 2024-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2304353&HistoricalAwards=false
• 关键词: SBIR; Phase; PenEEG; Objective; Assessment

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a mobile and compact Electroencephalography (EEG) concussion screening and recovery monitoring tool to reduce the time needed to seek proper patient care. Each year in the US, 5.5 million mild traumatic brain injury (TBI) or concussion cases are reported with athletes disproportionately affected. Most concussion assessments rely on subjective measures but have an estimated 50% false negative rate resulting in potentially harmful return to play. Current imaging tools detect structural versus functional injuries, and existing EEG systems are not readily usable for field applications. This system aims to provide a field usable, on-demand concussion screening tool that enables patients to seek care in a more rapid manner in the event of a concussive event. It will also reduce unnecessary emergency room visits during instances of non-concussions when used in conjunction with current assessment measures. The project presents an ultra-portable solution with quantifiable concussions measures. The innovation targets the $6.8 billion concussion care market opportunity within sports injury management, military health, and hospital sectors.This Small Business Innovation Research (SBIR) Phase I project will develop a handheld electroencephalogram (EEG) device designed to simplify data collection for long-term brain health tracking. The device is a two-channel tool that can be used at multiple locations on the head to conduct rapid, quantifiable brain assessments. The system aims to overcome the current size limitations and training required for current brain wave-measuring equipment. The size and portability of the device enables use across a variety of situations including sports events, military applications, or at home/on-base during recovery. The project aims to address two technical challenges: developing a system to guide untrained users in effectively positioning the device to collect high-quality data and developing a discriminant function to sense a series of acute brain wave signal changes in individuals over time for detecting concussions. The objective of this project is to develop a usable prototype with suitable sensitivity and specificity when compared to current diagnostic screening measures.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项小型企业创新研究（SBIR）I期项目的更广泛的影响/商业潜力是一个移动和紧凑的脑电图（EEG）脑震荡筛查和恢复监测工具，以减少寻求适当患者护理所需的时间。每年在美国，据报道，受运动员受到的影响不成比例，每年有550万例轻度创伤性脑损伤（TBI）或脑震荡病例。大多数脑震荡评估都依赖于主观措施，但估计有50％的假阴性率，导致潜在有害的比赛回报。当前的成像工具检测结构性损伤与功能损伤，现有的EEG系统不容易用于现场应用。该系统旨在提供一个可用的现场，点播脑震荡筛查工具，该工具使患者在发生脑震荡时能够以更快的方式寻求护理。与当前评估措施一起使用时，它还将减少不必要的急诊室就诊。该项目提出了可量化的脑震荡措施的超便携式解决方案。 这项创新针对运动伤害管理，军事健康和医院领域的68亿美元脑震荡护理市场机会。这项小型企业创新研究（SBIR）I期项目将开发旨在简化数据收集长期脑脑健康跟踪数据的手持式脑电图（EEG）设备。该设备是一种两通道工具，可以在头部的多个位置使用，以进行快速，可量化的大脑评估。该系统旨在克服当前脑波测量设备所需的当前尺寸限制和训练。该设备的大小和可移植性使得在各种情况下都可以使用，包括体育赛事，军事应用或在恢复期间在家/基础上使用。该项目旨在应对两个技术挑战：开发一个系统，以指导未经训练的用户有效定位该设备以收集高质量数据并开发判别功能，以感知个人随着时间的流逝，个人中的急性脑波信号变化以检测脑震荡。该项目的目的是与当前的诊断筛查措施相比，开发具有适当灵敏度和特异性的可用原型。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子和更广泛影响的评估标准来通过评估来获得支持的。