Development of an effective vaccine for chlamydial infection: optimisation of a non-toxic cholera toxin-based adjuvant to generate a protective mucosal response

开发针对衣原体感染的有效疫苗：优化基于无毒霍乱毒素的佐剂以产生保护性粘膜反应

• 批准号: LP0884020
• 负责人: Prof Kenneth Beagley
• 金额: $ 7.23万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-05-31 至 2012-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0884020
• 关键词: Development; effective; vaccine; chlamydial; infection

Chlamydial genital infections are the most common sexually transmitted infection in Australia and the world and impose a major health burden on the community. Chlamydial infections are also associated with cardiovascular disease, Australia's biggest killer and asthma, another condition that has increased significantly in prevalence in the past 10 years. This project will evaluate the effectiveness of a new adjuvant as a first step towards the development of a vaccine to target these important infections.

衣原体生殖器感染是澳大利亚和世界上最常见的性传播感染，对社区造成重大健康负担。衣原体感染还与澳大利亚最大杀手心血管疾病和哮喘有关，哮喘是过去10年患病率显着增加的另一种疾病。该项目将评估一种新佐剂的有效性，作为开发针对这些重要感染的疫苗的第一步。