Specificity of Chlamydia pneumoniae for humans : analysis of previous cross-host transmission events and the role of tryptophan availability in host specificity

肺炎衣原体对人类的特异性：分析先前的跨宿主传播事件以及色氨酸可用性在宿主特异性中的作用

• 批准号: nhmrc : 1004666
• 负责人: Prof Kenneth Beagley
• 金额: $ 27.58万
• 依托单位: University of the Sunshine Coast
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/specificity-chlamydia-pneumoniae-host-specificity/109060
• 关键词: Specificity; Chlamydia; pneumoniae; humans; analysis

Chlamydia are major causes of sexually transmitted disease but they also cause respiratory disease (Chlamydia pneumoniae) which is widespread across Australia and indeed the whole world (80% of people have been infected at some time in their life). Recent results suggest that the respiratory infections in humans came from animals and in this project we aim to identify which animals might have transmitted this infection to humans and determine if there is a continuing risk. We also plan to determine what defines animal versus human infections.

衣原体是性传播疾病的主要原因，但它们也会引起呼吸道疾病(肺炎衣原体)，这种疾病在澳大利亚乃至全世界都很普遍(80%的人在一生中的某个时候被感染)。最近的结果表明，人类的呼吸道感染来自动物，在这个项目中，我们的目标是确定哪些动物可能将这种感染传播给人类，并确定是否存在持续的风险。我们还计划确定动物感染与人类感染的定义。