Postdoctoral Fellowship: MPS-Ascend: Cyclodextrin-Poly(ethylene glycol)-Based Dynamic Covalent Networks

非技术性总结：这项研究将在布法罗大学进行，重点是与可持续性有关的社会方面。 它涉及开发和研究先进的聚合物材料，其分子可以形成可以动态断裂和重组的网络（“动态共价网络”）。 它们可能在烟气分离和从水系统中去除危险化学品（包括工业污染物和有害生物分子）方面提供高性能。如果成功，研究活动可以影响化学，材料，膜科学和生物医学科学。该项目的研究成果将通过出版物和演讲传播。研究参与人数不足的本科生将通过纽约州立大学LSAMP计划安排。该项目将包括多方面的教育工作，包括外展，以帮助促进科学教育在布法罗的公立学校，其中包括许多学生从代表性不足的groups.Technical摘要：环糊精（CD）为基础的聚合物是有前途的材料膜分离和其他应用。动态共价聚合物网络也吸引了相当大的兴趣，由于其自我修复和其他显着的性能。该项目的核心假设是基于CD的动态共价聚合物网络可以作为具有自修复特性和显著分离性能的新型膜材料。因此，本项目将研究具有β-CD（CD的代表形式）和聚乙二醇（PEG）链与动态氨基甲酸酯键连接的结构单元的动态共价网络。研究目标是：1）建立基于CD-PEG的动态共价网络的合成方法，2）理解它们的结构-性质关系，3）检查它们在二氧化碳（CO2）分离和从水相中去除危险化学品中的应用。首先制备具有动态氨基甲酸酯键的CD-PEG-甲基丙烯酸酯缀合物，然后光固化以得到基于CD-PEG的动态共价网络。 将对网络的物理化学、机械和自愈性能进行表征和研究。最后，将制备基于CD-PEG的共价动态网络膜，用于CO2/N2分离和从水相中去除全氟辛酸、胆固醇和尿酸的研究。该奖项反映了NSF的法定使命，并被认为是值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估的支持。

NON-TECHNICAL SUMMARY:This research, to be carried out at the University of Buffalo, is focused on societal aspects relevant to sustainability. It involves development and study of advanced polymeric materials whose molecules can form networks that can be broken and reconstituted dynamically ("dynamic covalent networks"). They can potentially offer high performance on flue gas separation and the removal of hazardous chemicals (including both industrial pollutants and harmful biomolecules) from aqueous systems. If successful, the research activities can impact chemistry, materials, membrane science, and biomedical science. The research results of this project will be disseminated through publications and presentations. Research participation of underrepresented undergraduate students will be arranged through the SUNY LSAMP program. The project will incorporate multifaceted educational efforts including outreach to help promote science education in Buffalo’s public schools which include many students from underrepresented groups.TECHNICAL SUMMARY:Cyclodextrin (CD)-based polymers are promising materials for membrane separation and other applications. Dynamic covalent polymer networks have also attracted considerable interest due to their self-healing and other remarkable properties. The core hypothesis of this project is that CD-based dynamic covalent polymer networks can serve as novel membrane materials with self-healing properties and significant separation performance. Accordingly, dynamic covalent networks with building units of β-CD (a representative form of CD) and poly(ethylene glycol) (PEG) chain linking with dynamic urethane bonds will be investigated in this project. The research objectives are: 1) to establish the synthetic approach to CD-PEG-based dynamic covalent networks, 2) to understand their structure-property relationships, and 3) to examine their applications for carbon dioxide (CO2) separation and removal of hazardous chemicals from aqueous phases. CD-PEG-methacrylate conjugates having dynamic urethane bonds will be prepared first and then photocured to give the CD-PEG-based dynamic covalent networks. Characterization and studies of physiochemical, mechanical and self-healing properties of the networks will be performed. Finally, membranes of CD-PEG-based covalent dynamic networks will be prepared for studies on CO2/N2 separation and removal of perfluorooctanoic acid, cholesterol, and uric acid from aqueous phase..This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.