Postdoctoral Fellowship: MPS-Ascend: Cyclodextrin-Poly(ethylene glycol)-Based Dynamic Covalent Networks

非技术摘要：这项研究将在布法罗大学进行，重点是与可持续发展相关的社会方面。它涉及先进聚合物材料的开发和研究，这些材料的分子可以形成可以动态断裂和重组的网络(动态共价网络)。它们可能在烟气分离和从水系统中去除危险化学物质(包括工业污染物和有害生物分子)方面提供高性能。如果成功，这些研究活动可能会影响化学、材料、膜科学和生物医学科学。该项目的研究成果将通过出版物和演示文稿进行传播。代表人数不足的本科生将通过纽约州立大学LSAMP计划安排参加研究。该项目将结合多方面的教育努力，包括帮助在布法罗的公立学校推广科学教育，其中包括许多来自代表不足的群体的学生。技术摘要：环糊精(CD)聚合物是一种很有前途的膜分离和其他应用材料。动态共价聚合物网络由于其自愈合和其他显着的性质也引起了人们的极大兴趣。本项目的核心假设是基于镉的动态共价聚合物网络可以作为一种新型的膜材料，具有自愈合性能和显著的分离性能。因此，本项目将研究以β-CD(CD的一种典型形式)和聚乙二醇链为结构单元，以动态氨酯键连接的动态共价网络。研究的目的是：1)建立基于CD-PEG的动态共价网络的合成方法，2)了解它们的结构-性质关系，3)考察它们在二氧化碳(CO2)分离和水相中去除危险化学品方面的应用。首先制备具有动态氨基甲酸酯键的CD-聚乙二醇甲基丙烯酸酯共轭化合物，然后光固化得到基于CD-聚乙二醇基的动态共价网络。将对网络的物理化学、机械和自愈特性进行表征和研究。最后，将制备基于CD-PEG的共价动态网络膜，用于二氧化碳/氮气的分离和从水相中去除全氟辛酸、胆固醇和尿酸的研究。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

NON-TECHNICAL SUMMARY:This research, to be carried out at the University of Buffalo, is focused on societal aspects relevant to sustainability. It involves development and study of advanced polymeric materials whose molecules can form networks that can be broken and reconstituted dynamically ("dynamic covalent networks"). They can potentially offer high performance on flue gas separation and the removal of hazardous chemicals (including both industrial pollutants and harmful biomolecules) from aqueous systems. If successful, the research activities can impact chemistry, materials, membrane science, and biomedical science. The research results of this project will be disseminated through publications and presentations. Research participation of underrepresented undergraduate students will be arranged through the SUNY LSAMP program. The project will incorporate multifaceted educational efforts including outreach to help promote science education in Buffalo’s public schools which include many students from underrepresented groups.TECHNICAL SUMMARY:Cyclodextrin (CD)-based polymers are promising materials for membrane separation and other applications. Dynamic covalent polymer networks have also attracted considerable interest due to their self-healing and other remarkable properties. The core hypothesis of this project is that CD-based dynamic covalent polymer networks can serve as novel membrane materials with self-healing properties and significant separation performance. Accordingly, dynamic covalent networks with building units of β-CD (a representative form of CD) and poly(ethylene glycol) (PEG) chain linking with dynamic urethane bonds will be investigated in this project. The research objectives are: 1) to establish the synthetic approach to CD-PEG-based dynamic covalent networks, 2) to understand their structure-property relationships, and 3) to examine their applications for carbon dioxide (CO2) separation and removal of hazardous chemicals from aqueous phases. CD-PEG-methacrylate conjugates having dynamic urethane bonds will be prepared first and then photocured to give the CD-PEG-based dynamic covalent networks. Characterization and studies of physiochemical, mechanical and self-healing properties of the networks will be performed. Finally, membranes of CD-PEG-based covalent dynamic networks will be prepared for studies on CO2/N2 separation and removal of perfluorooctanoic acid, cholesterol, and uric acid from aqueous phase..This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.