Equipment: MRI: Track 1 Acquisition of an Orbitrap Exploris 240 High-Resolution LC-MS for Research, Education, and Outreach at The University of Southern Mississippi (USM)

南密西西比大学被授予获得最先进的高分辨率液体色谱-质谱仪系统。该仪器将允许研究生和本科生在高分辨率质谱学方面获得适销对路的技能。购买该仪器将提高本科生和研究生在广泛的具有生物和化学意义的项目中进行研究的能力，从而提高他们的教育经验。南密西西比大学将使用该工具向当地高中推广，让学生接触到各种STEM职业机会和社会上科学素养的重要性。该工具将支持的研究有助于在各种生物过程中促进我们对基础科学的理解。该仪器将允许对这些生物过程进行研究，并提出新的假设，以洞察生物启发材料的发展、寄生虫驱动的食物过敏以及多肽在骨质疏松症中的作用。该仪器的其他用途将包括研究新催化过程中的反应机理，以帮助合成重要分子，并开发新的分子传感器来识别对环境有毒的化学物质。该项目由MRI、主要仪器研究计划和既定的刺激竞争研究计划(EPSCoR)联合资助。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

An award is made to the University of Southern Mississippi to acquire a state-of-the-art high-resolution liquid chromatography-mass spectrometer system. The instrument will allow graduate and undergraduate students to gain marketable skills in high-resolution mass spectrometry. Acquisition of the instrument will advance the educational experiences of undergraduate and graduate students by enhancing their ability to conduct research in a broad range of projects of biological and chemical significance. The University of Southern Mississippi will use the instrument for outreach to local high schools to expose students to the various STEM career opportunities and the importance of scientific literacy in society.The research this instrument will support helps advance our understanding of the fundamental science in various biological processes. The instrument will allow the study of these biological processes and the proposing of new hypotheses that can provide insight into the development of bio-inspired materials, parasite-driven food allergies, and the role of peptides in osteoporosis. Other uses of the instrument will include the study of reaction mechanisms in new catalytic processes to aid in the synthesis of important molecules and to develop new molecular sensors to identify chemicals that are toxic to the environment.This project is jointly funded by MRI, the Major Instrumentation Research Program, and the Established Program to Stimulate Competitive Research (EPSCoR).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.