MRI: Track 3 Acquisition of Helium Recovery Equipment at West Virginia University
MRI:第 3 轨道采购西弗吉尼亚大学氦回收设备
基本信息
- 批准号:2320495
- 负责人:
- 金额:$ 30.1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-09-01 至 2026-08-31
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
This award is jointly supported by the Major Research Instrumentation, the Chemistry Research Instrumentation programs, and the Established Program to Stimulate Competitive Research in response to the solicitation of proposals that promote the recovery, recycle, and/or reuse of helium, which was initiated by the CHIPS and Science Act of 2022. West Virginia University is acquiring a helium recovery system to capture and reliquefy helium from five NMR spectrometers to support the research of Professor Terry Gullion along with colleagues Gregory Dudley, Brian Popp, Jessica Hoover, and Carsten Milsmann. This equipment supports research in the areas of synthetic organic and inorganic chemistry, medicinal and structural biochemistry, physical organic chemistry, and NMR methodology development. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. Using the intrinsic magnetic properties of atomic nuclei, it is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The superconducting magnets of these instruments rely on regular deliveries of liquid helium to maintain their operation. However, the instability in the helium supply due to global and national challenges jeopardizes research programs relying on NMR spectroscopy. A helium recovery system collects the helium boiloff from the superconducting magnets of NMR spectrometers and then reliquefies the helium for reuse. This equipment supports the educational, research, and teaching efforts of students, including undergraduates from groups underrepresented in STEM and first-generation students, at all levels in multiple departments and the surrounding community. This award is aimed at supporting research and education at all levels. Specifically, this helium recovery system collects the helium boiloff for reliquefication and reuse from the superconducting magnets which sustains the operation of the institution’s five NMR spectrometers. The NMR instrumentation supported by this equipment enables research projects focused on chemical synthesis and methodology, medicinal chemistry, and reaction technology development. The research supported also involves the development and mechanistic study of catalytic oxidation reactions and sustainable (photo)chemistry with earth-abundant metals. Additionally, the recovery system aids in supporting investigations focusing on the methodology development and optimization using organometallic catalysis and the development of protein-protein interaction inhibitors. Other research areas include the development of new MRI contrast agents and single molecule magnets, NMR methodology development, and the characterization of insect wing membranes using solid-state NMR.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
该奖项由重大研究仪器、化学研究仪器计划和既定的激励竞争性研究计划共同支持,以回应由2022年芯片和科学法案发起的促进氦回收、循环和/或再利用的建议的征集。西弗吉尼亚大学正在购买一套氦回收系统,以从五台核磁共振光谱仪中捕获和释放氦,以支持特里·古利安教授及其同事格雷戈里·达德利、布莱恩·波普、杰西卡·胡佛和卡斯滕·米尔斯曼的研究。该设备支持合成有机化学和无机化学、药物和结构生物化学、物理有机化学和核磁共振方法开发等领域的研究。核磁共振波谱是化学家用来阐明分子结构的最有力的工具之一。利用原子核的固有磁性,它被用来识别未知物质,表征分子内原子的特定排列,并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说,获得最先进的核磁共振光谱仪是必不可少的。这些仪器的超导磁体依靠定期输送的液氦来维持其运行。然而,由于全球和国家挑战导致的氦供应不稳定,危及依赖于核磁共振波谱的研究计划。氦回收系统从核磁共振光谱仪的超导磁铁中收集氦沸腾,然后重新回收氦以供重复使用。该设备支持学生的教育、研究和教学努力,包括STEM中代表性不足的群体的本科生和第一代学生,以及多个部门和周围社区的各级学生。该奖项旨在支持所有级别的研究和教育。具体地说,这个氦回收系统收集超导磁体中的氦沸腾,用于再液化和再利用,超导磁体支持该研究所的五台核磁共振光谱仪的运行。该设备支持的核磁共振仪器使研究重点放在化学合成和方法学、药物化学和反应技术开发上。所支持的研究还涉及对富含地球的金属的催化氧化反应和可持续(照片)化学的发展和机理研究。此外,回收系统有助于支持侧重于使用有机金属催化的方法学开发和优化以及蛋白质-蛋白质相互作用抑制剂的开发的研究。其他研究领域包括开发新的核磁共振造影剂和单分子磁体,核磁共振方法的开发,以及使用固态核磁共振对昆虫翼膜进行表征。该奖项反映了NSF的法定使命,并通过使用基金会的智力优势和更广泛的影响审查标准进行评估,被认为值得支持。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Terry Gullion其他文献
High field <sup>17</sup>O solid-state NMR study of alanine tripeptides
- DOI:
10.1016/j.jmr.2007.11.006 - 发表时间:
2008-02-01 - 期刊:
- 影响因子:
- 作者:
Kazuo Yamauchi;Michi Okonogi;Hiromichi Kurosu;Masataka Tansho;Tadashi Shimizu;Terry Gullion;Tetsuo Asakura - 通讯作者:
Tetsuo Asakura
\ REAPDOR NMR as a Tool for Determing Secondary Strueture in Polyamides.
REAPDOR NMR 作为测定聚酰胺二级结构的工具。
- DOI:
- 发表时间:
2007 - 期刊:
- 影响因子:0
- 作者:
T.Rungsimanon;K.Yuyama;T.Sugiyama;H.Masuhara;他2名;Terry Gullion - 通讯作者:
Terry Gullion
Structure of Bombyx mori Silk Fibroin Studied by REDOR NMR Spectroscopy
利用 REDOR 核磁共振波谱研究家蚕丝素蛋白的结构
- DOI:
10.1295/polymj.26.1405 - 发表时间:
1994-12-01 - 期刊:
- 影响因子:2.700
- 作者:
Tetsuo Asakura;Akira Aoki;Makoto Demura;James M Joers;Richard C Rosanske;Terry Gullion - 通讯作者:
Terry Gullion
Terry Gullion的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Terry Gullion', 18)}}的其他基金
Development of MAS NMR RF Power and Spinning Speed Controllers and 1H-X Dipolar Recoupling Methods
MAS NMR RF 功率和旋转速度控制器以及 1H-X 偶极重耦合方法的开发
- 批准号:
1608149 - 财政年份:2016
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
Switch Angle Sample Spinning Probes and High Resolution Dipolar Recoupling with Quadrupolar Nuclei
切换角度样品旋转探针和四极核高分辨率偶极重耦合
- 批准号:
1152009 - 财政年份:2012
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
MRI: Acquisition of a 400-MHz NMR Spectrometer for Research and Teaching
MRI:购买 400 MHz NMR 波谱仪用于研究和教学
- 批准号:
1228336 - 财政年份:2012
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
High-Resolution SEDOR and Switch Angle Sample Spinning Probes for Dipolar Recoupling
用于偶极重耦合的高分辨率 SEDOR 和开关角样品旋转探针
- 批准号:
0846583 - 财政年份:2009
- 资助金额:
$ 30.1万 - 项目类别:
Continuing Grant
The Development of Dipole Recoupling Methods and The Characterization of Molecularly Doped Polymers
偶极子重耦合方法的发展和分子掺杂聚合物的表征
- 批准号:
0603697 - 财政年份:2006
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
Measuring Internuclear Distances by Solid-State NMR
通过固态核磁共振测量核间距
- 批准号:
0245126 - 财政年份:2002
- 资助金额:
$ 30.1万 - 项目类别:
Continuing Grant
Measuring Internuclear Distances by Solid-State NMR
通过固态核磁共振测量核间距
- 批准号:
0296132 - 财政年份:2001
- 资助金额:
$ 30.1万 - 项目类别:
Continuing Grant
Measuring Internuclear Distances by Solid-State NMR
通过固态核磁共振测量核间距
- 批准号:
0091663 - 财政年份:2001
- 资助金额:
$ 30.1万 - 项目类别:
Continuing Grant
Measuring 13C-170 and 13C-14N Distances in Solids; NMR Technique Development
测量固体中的 13C-170 和 13C-14N 距离;
- 批准号:
9603624 - 财政年份:1997
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
Measuring 13C-170 and 13C-14N Distances in Solids; NMR Technique Development
测量固体中的 13C-170 和 13C-14N 距离;
- 批准号:
9796188 - 财政年份:1997
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
相似海外基金
MRI: Track 1 Acquisition of a High-Performance Computing System at New Mexico Tech
MRI:新墨西哥理工学院高性能计算系统的第一轨道采购
- 批准号:
2320162 - 财政年份:2024
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
Equipment: MRI: Track 2 Acquisition of a Novel Performance-Driven 3D Imaging System for Extremely Noisy Objects (NPIX)
设备: MRI:第 2 道采购新型性能驱动的 3D 成像系统,用于极噪物体 (NPIX)
- 批准号:
2319708 - 财政年份:2023
- 资助金额:
$ 30.1万 - 项目类别:
Continuing Grant
MRI: Track 1 Acquisition of a High-Resolution Quadrupole Time-of-Flight Mass Spectrometer with Diverse Inlet and Ionization Capabilities for Chemical Analyses
MRI:轨道 1 采购具有多种入口和电离功能的高分辨率四极杆飞行时间质谱仪,用于化学分析
- 批准号:
2319939 - 财政年份:2023
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
MRI: Track 1: Acquisition of an Inductively Coupled Plasma Mass Spectrometer to Quantify Trace Metal Ions Enabling New Research and Research Training at Barnard College
MRI:轨道 1:购买电感耦合等离子体质谱仪来量化痕量金属离子,从而在巴纳德学院实现新的研究和研究培训
- 批准号:
2320054 - 财政年份:2023
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
MRI: Track 1 Acquisition of a Matrix-Assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometer for Analysis of Macromolecules
MRI:轨道 1 获取用于分析大分子的基质辅助激光解吸/电离飞行时间质谱仪
- 批准号:
2320090 - 财政年份:2023
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
MRI: Track 3 Acquisition of a Helium Liquefaction and Recovery System for METRIC NMR Laboratories at NC State
MRI:轨道 3 为北卡罗来纳州 METRIC NMR 实验室采购氦液化和回收系统
- 批准号:
2320092 - 财政年份:2023
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
Equipment: MRI Track 1: Acquisition of Flow Cytometer
设备:MRI 轨道 1:流式细胞仪的购置
- 批准号:
2320130 - 财政年份:2023
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
MRI: Track 1 Acquisition of a Nanoparticle Tracking Analyzer to Enhance Nanomaterial Research
MRI:Track 1 采购纳米粒子跟踪分析仪以加强纳米材料研究
- 批准号:
2320201 - 财政年份:2023
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
Research Infrastructure: MRI: Track 2 Acquisition of Data Observation and Computation Collaboratory (DOCC)
研究基础设施:MRI:数据观察和计算合作实验室 (DOCC) 的轨道 2 采集
- 批准号:
2320261 - 财政年份:2023
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant
Equipment: MRI: Track 2 Acquisition of a Hydraulic and Sediment Recirculation Flume to Advance Fundamental Research in Urban Stormwater and Fluvial Processes
设备: MRI:轨道 2 获取水力和沉积物再循环水槽,以推进城市雨水和河流过程的基础研究
- 批准号:
2320356 - 财政年份:2023
- 资助金额:
$ 30.1万 - 项目类别:
Standard Grant