MRI: Track 1 Acquisition of an X-ray Diffraction Instrument for Research and Education in Southeast Wisconsin

MRI：轨道 1 采购 X 射线衍射仪器，用于威斯康星州东南部的研究和教育

• 批准号: 2320762
• 负责人: Adam Fiedler
• 金额: $ 35.02万
• 依托单位: Marquette University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2026-08-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2320762&HistoricalAwards=false
• 关键词: MRI; Track; Acquisition; ray; Diffraction

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation Programs. Marquette University is acquiring a diffractometer with an advanced detector and X-ray optics to support the research of Professors Fiedler, Gardinier, and Reiter. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The instrument will be utilized in multiple research areas, including inorganic chemistry, magnetic materials, catalysis, biochemistry, and pharmaceutical studies. Training opportunities in crystallographic analysis will be provided to undergraduate and graduate students in the Chemistry and Biological Sciences Departments of Marquette University, as well as nearby colleges and universities. In addition, this instrumentation will benefit chemical industry in Southeast Wisconsin, as these companies often require X-ray diffractometers to understand the structures of complex molecules and materials. The award is aimed at enhancing research and education at all levels. Research enabled by the instrument is focused on provide molecular structures to advance knowledge of coordination chemistry, magnetic materials, and transition-metal catalysis. The instrumentation will also enable studies of biomolecules, including enzymes and RNA/protein adducts. The X-ray diffractometer will be utilized by researchers at Marquette University, nearby colleges and universities, and companies in the region to obtain structural insights into drug targets, natural products, protein crystals, transition-metal complexes, and materials.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器和化学研究仪器计划共同支持。马奎特大学正在购买一台带有先进探测器和X射线光学器件的衍射仪，以支持Fiedler、Gardinier和Reiter教授的研究。 一般来说，X射线衍射仪允许准确和精确地测量分子的完整三维结构，包括键距和角度，并提供关于分子相对于相邻分子的空间排列的准确信息。该仪器将用于多个研究领域，包括无机化学，磁性材料，催化，生物化学和药学研究。 将为马奎特大学化学和生物科学系以及附近学院和大学的本科生和研究生提供晶体学分析方面的培训机会。 此外，这种仪器将有利于威斯康星州东南部的化学工业，因为这些公司经常需要X射线衍射仪来了解复杂分子和材料的结构。 该奖项旨在加强各级的研究和教育。该仪器的研究重点是提供分子结构，以促进配位化学，磁性材料和过渡金属催化的知识。 该仪器还将使生物分子的研究，包括酶和RNA/蛋白质加合物。该X射线衍射仪将被马奎特大学、附近学院和大学的研究人员以及该地区的公司用于获得对药物靶点、天然产物、蛋白质晶体、过渡金属络合物和材料的结构见解。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。