MRI: Track 1 Acquisition of an X-ray Diffraction Instrument for Research and Education in Southeast Wisconsin

该奖项由主要研究仪器项目和化学研究仪器项目共同支持。马奎特大学正在购买一台具有先进探测器和X射线光学的衍射仪，以支持菲德勒、加迪尼尔和赖特教授的研究。通常，X射线衍射仪可以准确和精确地测量分子的完整三维结构，包括键距离和角度，并提供关于分子相对于邻近分子的空间排列的准确信息。该仪器将用于多个研究领域，包括无机化学、磁性材料、催化、生物化学和药学研究。马奎特大学化学和生物科学系以及附近的学院和大学的本科生和研究生将获得晶体分析方面的培训机会。此外，这种仪器将使威斯康星州东南部的化学工业受益，因为这些公司经常需要X射线衍射仪来了解复杂分子和材料的结构。该奖项旨在加强各级的研究和教育。该仪器的研究重点是提供分子结构，以促进配位化学、磁性材料和过渡金属催化的知识。该仪器还将使生物分子的研究成为可能，包括酶和RNA/蛋白质加合物。马奎特大学的研究人员、附近的学院和大学以及该地区的公司将使用X射线衍射仪来获得对药物靶标、天然产品、蛋白质晶体、过渡金属络合物和材料的结构洞察。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation Programs. Marquette University is acquiring a diffractometer with an advanced detector and X-ray optics to support the research of Professors Fiedler, Gardinier, and Reiter. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The instrument will be utilized in multiple research areas, including inorganic chemistry, magnetic materials, catalysis, biochemistry, and pharmaceutical studies. Training opportunities in crystallographic analysis will be provided to undergraduate and graduate students in the Chemistry and Biological Sciences Departments of Marquette University, as well as nearby colleges and universities. In addition, this instrumentation will benefit chemical industry in Southeast Wisconsin, as these companies often require X-ray diffractometers to understand the structures of complex molecules and materials. The award is aimed at enhancing research and education at all levels. Research enabled by the instrument is focused on provide molecular structures to advance knowledge of coordination chemistry, magnetic materials, and transition-metal catalysis. The instrumentation will also enable studies of biomolecules, including enzymes and RNA/protein adducts. The X-ray diffractometer will be utilized by researchers at Marquette University, nearby colleges and universities, and companies in the region to obtain structural insights into drug targets, natural products, protein crystals, transition-metal complexes, and materials.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.