I-Corps: Non-Invasive Software Tool for Risk Assessment of Intracranial Aneurysms (IA)

这个i-Corps项目的更广泛的影响/商业潜力是开发一种软件工具，用于对脑动脉瘤进行非侵入性风险评估。目前，医疗行业越来越倾向于采用侵入性较小的评估方法，简化医疗专业人员的任务，增强他们对脑动脉瘤的理解。这项技术可以将患者从不必要的危险程序中解救出来，并简化诊断和治疗分析工作流程，加强手术前规划和治疗后监测。此外，这项技术旨在在医疗保健过程的早期提供关键信息。医疗保健提供者将受益，因为该系统有助于准确维护每个患者的索赔、治疗记录和相关风险。这些数据反过来又使医疗保健提供者能够对个别患者进行预测性规划，有助于更好地对医疗保健行业的整体患者护理和资源管理做出贡献。这个i-Corps项目基于开发一种非侵入性软件工具，旨在增强对颅内动脉瘤的风险分析。该技术将先进的成像技术与计算动力学和人工智能/机器学习(AI/ML)分析相结合，提供对颅内动脉瘤风险的全面评估。通过使用Navier-Stokes方程重建血管和模拟血液流动，该工具改进了成像方式。AI/ML算法分析这些数据，为个性化治疗计划提供有价值的见解。该技术旨在为每个患者提供量身定做的动态风险评估，确保更准确和有效的结果。AI/ML洞察力基于与动脉瘤生长和进展相关的患者特定生物标记物，从而能够对个别病例进行彻底分析。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

The broader impact/commercial potential of this I-Corps project is the development of a software tool for a non-invasive risk assessment of cerebral aneurysms. Currently, there is a growing trend in the medical industry towards less invasive assessment methods that streamline the tasks of medical professionals and augment their comprehension of cerebral aneurysms. This technology may save patients from unnecessary risky procedures and streamline diagnostic and treatment analysis workflow, enhancing pre-surgical planning and post-treatment monitoring. In addition, the technology is designed to provide critical information early in the healthcare process. Healthcare providers will benefit as the system aids in accurately maintaining claims, treatment records, and associated risks for each patient. This data, in turn, enables healthcare providers to engage in predictive planning for individual patients, contributing to better overall patient care and resource management in the healthcare industry.This I-Corps project is based on the development of a non-invasive software tool designed to enhance risk analysis of intracranial aneurysms. The technology integrates advanced imaging techniques with computational dynamics and artificial intelligence/machine learning (AI/ML) analysis to provide a comprehensive assessment of intracranial aneurysm risks. By reconstructing blood vessels and simulating blood flow using Navier-Stokes equations, the tool improves imaging modalities. The AI/ML algorithms analyze this data, offering valuable insights for personalized treatment planning. The technology is designed to provide dynamic risk assessments tailored to each patient, ensuring more accurate and effective results. The AI/ML insights are grounded in patient-specific biomarkers related to aneurysm growth and progression, enabling a thorough analysis of individual cases.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.