Characterization of the Self-Assembly Process of Hydrophobins at Interfaces and in Solution (B11*)

界面和溶液中疏水蛋白自组装过程的表征 (B11*)

• 批准号: 276253528
• 金额: --
• 依托单位: Arbeitsbereich Physikalische und Theoretische Chemie
• 依托单位国家: 德国
• 项目类别: CRC/Transregios
• 财政年份: 2015
• 资助国家: 德国
• 起止时间: 2014-12-31 至 2018-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/276253528?language=en
• 关键词: Characterization; Self; Assembly; Process; Hydrophobins

This project aims at understanding the self-assembly process of a special class of small fungal proteins that are highly surface active and are called hydrophobins. Hydrophobins self-assemble into films composed of rodlets (fibrillar structures) or 2D crystalline sheets with interesting physico-chemical properties. The main goal of this project is to elucidate the self-assembly processes of hydrophobins at interfaces (mainly liquid/liquid and air/water interface) and their pre-assembly in solution mainly by applying methods of electron paramagnetic resonance (EPR) spectroscopy, together with surface-sensitive infrared-reflection-absorption spectroscopy (IRRAS).

该项目旨在了解一类特殊的小真菌蛋白的自组装过程，这些蛋白具有高度的表面活性，被称为疏水蛋白。疏水蛋白自组装成由小棒（纤维状结构）或具有有趣的物理化学性质的2D结晶片组成的膜。本项目的主要目标是阐明疏水蛋白在界面（主要是液/液和空气/水界面）的自组装过程，以及它们在溶液中的预组装，主要是通过应用电子顺磁共振（EPR）光谱法，结合表面敏感红外反射吸收光谱（IRRAS）。