Nano-molecular structure and function of protein mini-compartments known as carboxysomes

称为羧基体的蛋白质微型隔室的纳米分子结构和功能

• 批准号: DP0769999
• 负责人: Prof Graeme Price
• 金额: $ 18.25万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0769999
• 关键词: Nano; molecular; structure; function; protein

Intriguing protein nano-structures, present in blue-green algae and known as carboxysomes, act as tiny compartments where CO2 can be fixed into simple sugars at high efficiency. This important photosynthetic process forms the basis of global primary productivity on this planet, but most land-based CO2 fixation lacks the efficiency seen in blue-greens. This research aims to determine how the several proteins that make up carboxysomes come together to makeup carboxysome nano-structures and how these function to enhance rates of CO2 fixation. A more thorough understanding of the carboxysome is likely to have potential applications in industrial nano-technology and improvements in crop productivity.

有趣的蛋白质纳米结构，存在于蓝绿藻中，被称为羧基体，作为微小的隔间，二氧化碳可以高效地固定到单糖中。这一重要的光合作用过程构成了地球上全球初级生产力的基础，但大多数陆基二氧化碳固定缺乏蓝绿色的效率。这项研究旨在确定构成羧基体的几种蛋白质如何聚集在一起构成羧基体纳米结构，以及这些蛋白质如何发挥作用以提高CO2固定率。对羧基体的更深入了解可能在工业纳米技术和提高作物产量方面具有潜在的应用。